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MqsA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
mqsRA_mRNA csgDEFG_mRNA RpoA RpoA CsgD MqsA CsgG RpoS RpoB CsgE RpoS MqsR RpoB mqsRA CspD mRNA CsgF MqsR cspD cspD_mRNA RpoC csgDEFG CsgA CsgE MqsA RpoC rpoS_mRNA CsgG mRNA fragments rpoS CsgA_Ext


Gensor Unit       
Name: MqsA
Classification:
Groups: Transcription
Gene Ontology Terms (GO): biological_process GO:0006352 - DNA-templated transcription, initiation
GO:0090502 - RNA phosphodiester bond hydrolysis, endonucleolytic
GO:0022610 - biological adhesion
GO:0008156 - negative regulation of DNA replication
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0017148 - negative regulation of translation
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cellular_component GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031246 - intrinsic component of periplasmic side of cell outer membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
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molecular_function GO:0003677 - DNA binding
GO:0001216 - DNA-binding transcription activator activity
GO:0003700 - DNA-binding transcription factor activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0003723 - RNA binding
GO:0001000 - bacterial-type RNA polymerase core enzyme binding
GO:0004519 - endonuclease activity
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Components:
  Function Name Type
  simple_molecule CsgA simple_molecule
  simple_molecule CsgA_Ext simple_molecule
  protein CsgD protein
  protein CsgE protein
  complex CsgE-CsgG complex
  protein CsgF protein
  protein CsgG protein
  protein CspD protein
  protein MqsA protein
  complex MqsA-MqsR complex
  protein MqsR protein
  protein RpoA protein
  protein RpoB protein
  complex RpoB-RpoC-RpoA-RpoS complex
  protein RpoC protein
  protein RpoS protein
  gene csgDEFG gene
  RNA csgDEFG_mRNA RNA
  gene cspD gene
  RNA cspD_mRNA RNA
  simple_molecule mRNA simple_molecule
  simple_molecule mRNA fragments simple_molecule
  gene mqsRA gene
  RNA mqsRA_mRNA RNA
  gene rpoS gene
  RNA rpoS_mRNA RNA


Reactions       
Showing 17 reactions
MqsA csgDEFG csgDEFG_mRNA
Name: csgDEFG -> csgDEFG_mRNA
Description: Transcription of transcription unit csgDEFG. Reaction inhibition by MqsA.
Type: transcription
Pathway Components: csgDEFG - MqsA -> csgDEFG_mRNA
Components:
Function Name Type
inhibitor MqsA protein
reactant csgDEFG gene
product csgDEFG_mRNA RNA
MqsA cspD cspD_mRNA
Name: cspD -> cspD_mRNA
Description: Transcription of transcription unit cspD. Reaction inhibition by MqsA.
Type: transcription
Pathway Components: cspD - MqsA -> cspD_mRNA
Components:
Function Name Type
inhibitor MqsA protein
reactant cspD gene
product cspD_mRNA RNA
MqsA mqsRA mqsRA_mRNA
Name: mqsRA -> mqsRA_mRNA
Description: Transcription of transcription unit mqsRA. Reaction inhibition by MqsA.
Type: transcription
Pathway Components: mqsRA - MqsA -> mqsRA_mRNA
Components:
Function Name Type
inhibitor MqsA protein
reactant mqsRA gene
product mqsRA_mRNA RNA
MqsA rpoS rpoS_mRNA
Name: rpoS -> rpoS_mRNA
Description: Transcription of transcription unit rpoS. Reaction inhibition by MqsA.
Type: transcription
Pathway Components: rpoS - MqsA -> rpoS_mRNA
Components:
Function Name Type
inhibitor MqsA protein
reactant rpoS gene
product rpoS_mRNA RNA
csgDEFG_mRNA CsgD
Name: csgDEFG_mRNA -> CsgD
Description: Translation of CsgD
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgD
Components:
Function Name Type
product CsgD protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgE
Name: csgDEFG_mRNA -> CsgE
Description: Translation of CsgE
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgE
Components:
Function Name Type
product CsgE protein
reactant csgDEFG_mRNA RNA
CsgG + CsgE CsgE-CsgG
Name: CsgG + CsgE -> CsgE-CsgG
Description: Reaction transforming CsgG, CsgE into CsgE-CsgG
Type: state transition
Pathway Components: CsgG + CsgE -> CsgE-CsgG
Components:
Function Name Type
reactant CsgE protein
product CsgE-CsgG complex
reactant CsgG protein
CsgE-CsgG CsgA_Ext CsgA
Name: CsgA_Ext -> CsgA
Description: Transport of CsgA_Ext through a bacterial membrane, leading to the presence of CsgA inside the cell.
Type: transport
Pathway Components: CsgA_Ext - CsgE-CsgG -> CsgA
Components:
Function Name Type
product CsgA simple_molecule
reactant CsgA_Ext simple_molecule
catalyzer CsgE-CsgG complex
csgDEFG_mRNA CsgF
Name: csgDEFG_mRNA -> CsgF
Description: Translation of CsgF
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgF
Components:
Function Name Type
product CsgF protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgG
Name: csgDEFG_mRNA -> CsgG
Description: Translation of CsgG
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgG
Components:
Function Name Type
product CsgG protein
reactant csgDEFG_mRNA RNA
cspD_mRNA CspD
Name: cspD_mRNA -> CspD
Description: Translation of CspD
Type: translation
Pathway Components: cspD_mRNA -> CspD
Components:
Function Name Type
product CspD protein
reactant cspD_mRNA RNA
mqsRA_mRNA MqsR
Name: mqsRA_mRNA -> MqsR
Description: Translation of MqsR
Type: translation
Pathway Components: mqsRA_mRNA -> MqsR
Components:
Function Name Type
product MqsR protein
reactant mqsRA_mRNA RNA
MqsA + MqsR MqsA-MqsR
Name: MqsA + MqsR -> MqsA-MqsR
Description: Reaction transforming MqsA, MqsR into MqsA-MqsR
Type: state transition
Pathway Components: MqsA + MqsR -> MqsA-MqsR
Components:
Function Name Type
reactant MqsA protein
product MqsA-MqsR complex
reactant MqsR protein
MqsR mRNA mRNA fragments
Name: mRNA -> mRNA fragments
Description: Reaction transforming mRNA into mRNA fragments
Type: state transition
Pathway Components: mRNA - MqsR -> mRNA fragments
Components:
Function Name Type
catalyzer MqsR protein
reactant mRNA simple_molecule
product mRNA fragments simple_molecule
mqsRA_mRNA MqsA
Name: mqsRA_mRNA -> MqsA
Description: Translation of MqsA
Type: translation
Pathway Components: mqsRA_mRNA -> MqsA
Components:
Function Name Type
product MqsA protein
reactant mqsRA_mRNA RNA
rpoS_mRNA RpoS
Name: rpoS_mRNA -> RpoS
Description: Translation of RpoS
Type: translation
Pathway Components: rpoS_mRNA -> RpoS
Components:
Function Name Type
product RpoS protein
reactant rpoS_mRNA RNA
RpoB + RpoA + RpoS + RpoC RpoB-RpoC-RpoA-RpoS
Name: RpoB + RpoA + RpoS + RpoC -> RpoB-RpoC-RpoA-RpoS
Description: Reaction transforming RpoB, RpoA, RpoS, RpoC into RpoB-RpoC-RpoA-RpoS
Type: state transition
Pathway Components: RpoB + RpoA + RpoS + RpoC -> RpoB-RpoC-RpoA-RpoS
Components:
Function Name Type
reactant RpoA protein
reactant RpoB protein
product RpoB-RpoC-RpoA-RpoS complex
reactant RpoC protein
reactant RpoS protein
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