RegulonDB RegulonDB

ModE Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
deoxy-D-ribose 1-phosphate dipeptide_Ext acceptors nitrate NapA HycI A(H2) NarX NapB hycABCDEFGHI HycF dmsABC_mRNA narXL CcmE adenosine HycD OppD nebularine NapF MppA OppB ubiquinone CcmB methionine HycH adenine guanosine hydrogen MoaA diphosphate DmsC napFDAGHBC-ccmABCDEFGH_mRNA Ala-gamma-D-Glu-Dap_Ext DeoB HycC CcmH H2Dtpp-mP modABC_mRNA SAM deoxyadenosine deoCABD NapA CcmE oligopeptide reduced Cytochrome C protein CcmF guanosine-triphosphate NapC narXL_mRNA molybdate_Ext oxidized hydrogenase 3 CcmF molybdate moaABCDE_mRNA CcmD oppABCDF 5'-deoxyadenosine ribose-1-phosphate moaABCDE deoCABD_mRNA guanine 2-deoxy-D-ribose 5-phosphate OppA hycABCDEFGHI_mRNA NarL DmsB thymine CcmG CcmG DmsC uracil precursor of large subunit of hydrogenase 3 ModC ferri c-type cytochrome CcmE DeoC protoheme IX_Ext MPT-Synthase-small-subunits OppD MppA ModE MoaE HycC oppABCDF_mRNA thymidine ModA MoaB menaquinol NapH HycE DeoD cPMP NapD C terminal 32 amino-acid peptide deoxyuridine CcmH molybdate HycF ubiquinol MoaC DMSO HycA CcmC napFDAGHBC-ccmABCDEFGH phosphate OppD OppA deoxyguanosine glyceraldehyde-P ModB HycG Oxidized-NapC-proteins OppC 3',8-cH2GTP dimethylsulfide nitrite dmsABC inosine CcmA ModA OppF Ala-gamma-D-Glu-Dap large subunit of hydrogenase 3 CcmA dipeptide HycD NapG ModB MoaD MoaD CcmB DmsA ModC NapH DeoA DmsA OppF oligopeptide_Ext OppC NapG ribose-5P CcmC OppF ethanal deoxyinosine thiocarboxylated small subunit of molybdopterin synthase H2Dtpp-mADP hypoxanthine modABC DmsB vitamin K2 CcmD HycB OppC HycG Reduced-NapC-proteins HycE MoaE OppB NapB ModE reduced hydrogenase 3 protoheme IX HycB purine base OppB phosphate phosphate guanine adenosine


Gensor Unit       
Name: ModE
Description: Molecular biology level
Detailed: In the presence of molybdate, ModE positively regulates the expression of genes required for proteolysis, formate oxidation, Mo-molybdopterin cofactot biosynthetic process, denitrification pathway, and negatively regulates the expression of oligopeptide transport, nucleoside metabolic process, molybdate ion transport and dimethyl sulfoxide metabolic process. Under these conditions, ModE is modified to ModE-molybdate, binds its target sites enabling in some cases and preventing in others the expression of its regulated genes. In the absence of Molybdate, ModE remains unmodified, unbinds its target sites preventing and enabling the expression of its regulated genes.
Less detailed: In the presence of molybdate, ModE positively regulates the expression of genes needed for proteolysis, formate oxidation, Mo-molybdopterin cofactot biosynthetic process, denitrification pathway, and negatively regulates the expression of oligopeptide transport, nucleoside metabolic process, molybdate ion transport and dimethyl sulfoxide metabolic process.

Physiology level
Detailed: The presence of molybdate induces the expression of genes involved with proteolysis, formate oxidation, Mo-molybdopterin cofactot biosynthetic process, denitrification pathway, and inhibits the expression of genes necessary for oligopeptide transport, nucleoside metabolic process, molybdate ion transport and dimethyl sulfoxide metabolic process. Under these conditions, the genes necessary for conversion of formate to CO2 and H2, proteolysis of hydrogenase 3 to a peptide, conversion of thiocarboxylated MoaD to molybdopterin and conversion of nitrate to nitrite are expressed, conversely the genes necessary for nucleoside conversion to nucleobases and conversion of dimethyl sulfoxide to dimethyl sulfide are not expressed.
Read more >
Classification:
Groups: Inorganic ion transport and metabolism
Posttranslational modification, protein turnover, chaperones
Carbohydrate transport and metabolism
Energy production and conversion
Signal transduction mechanisms
Amino acid transport and metabolism
Coenzyme transport and metabolism
Intracellular trafficking, secretion, and vesicular transport
Nucleotide transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0006015 - 5-phosphoribose 1-diphosphate biosynthetic process
GO:0042773 - ATP synthesis coupled electron transport
GO:0006777 - Mo-molybdopterin cofactor biosynthetic process
GO:0019645 - anaerobic electron transport chain
GO:0009061 - anaerobic respiration
GO:0016052 - carbohydrate catabolic process
Read more >
cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009390 - dimethyl sulfoxide reductase complex
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
GO:0009375 - ferredoxin hydrogenase complex
GO:0016021 - integral component of membrane
Read more >
molecular_function GO:0004645 - 1,4-alpha-oligoglucan phosphorylase activity
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0005524 - ATP binding
GO:0016887 - ATPase activity
GO:0015439 - ATPase-coupled heme transmembrane transporter activity
GO:0015412 - ATPase-coupled molybdate transmembrane transporter activity
GO:0015421 - ATPase-coupled oligopeptide transmembrane transporter activity
Read more >
Components:
  Function Name Type
  simple_molecule 2-deoxy-D-ribose 5-phosphate simple_molecule
  simple_molecule 3',8-cH2GTP simple_molecule
  simple_molecule 5'-deoxyadenosine simple_molecule
  simple_molecule A(H2) simple_molecule
  simple_molecule Ala-γ-D-Glu-Dap simple_molecule
  simple_molecule Ala-γ-D-Glu-Dap_Ext simple_molecule
  simple_molecule C terminal 32 amino-acid peptide simple_molecule
  protein CcmA protein
  protein CcmB protein
  protein CcmC protein
  protein CcmD protein
  complex CcmD-CcmB-CcmA-CcmE-CcmC complex
  protein CcmE protein
  complex CcmE-CcmF-CcmG-CcmH complex
  protein CcmF protein
  protein CcmG protein
  protein CcmH protein
  simple_molecule DMSO simple_molecule
  protein DeoA protein
  protein DeoB protein
  protein DeoC protein
  protein DeoD protein
  protein DmsA protein
  complex DmsA-DmsB-DmsC complex
  protein DmsB protein
  protein DmsC protein
  simple_molecule H2Dtpp-mADP simple_molecule
  simple_molecule H2Dtpp-mP simple_molecule
  protein HycA protein
  protein HycB protein
  protein HycC protein
  protein HycD protein
  complex HycD-HycC-HycF-HycG-HycB-HycE complex
  protein HycE protein
  protein HycF protein
  protein HycG protein
  protein HycH protein
  protein HycI protein
  simple_molecule MPT-Synthase-small-subunits simple_molecule
  protein MoaA protein
  protein MoaB protein
  protein MoaC protein
  protein MoaD protein
  complex MoaD-MoaE complex
  protein MoaE protein
  protein ModA protein
  protein ModB protein
  protein ModC protein
  complex ModC-ModB-ModA complex
  protein ModE protein
  complex ModE-molybdate complex
  protein MppA protein
  protein NapA protein
  protein NapB protein
  complex NapB-NapA complex
  protein NapC protein
  protein NapD protein
  protein NapF protein
  protein NapG protein
  complex NapG-NapH complex
  protein NapH protein
  protein NarL protein
  protein NarX protein
  protein OppA protein
  protein OppB protein
  complex OppB-OppC-OppD-OppF-MppA complex
  protein OppC protein
  complex OppC-OppD-OppF-OppB-OppA complex
  protein OppD protein
  protein OppF protein
  simple_molecule Oxidized-NapC-proteins simple_molecule
  simple_molecule Reduced-NapC-proteins simple_molecule
  simple_molecule SAM simple_molecule
  simple_molecule acceptors simple_molecule
  simple_molecule adenine simple_molecule
  simple_molecule adenosine simple_molecule
  simple_molecule cPMP simple_molecule
  gene deoCABD gene
  RNA deoCABD_mRNA RNA
  simple_molecule deoxy-D-ribose 1-phosphate simple_molecule
  simple_molecule deoxyadenosine simple_molecule
  simple_molecule deoxyguanosine simple_molecule
  simple_molecule deoxyinosine simple_molecule
  simple_molecule deoxyuridine simple_molecule
  simple_molecule dimethylsulfide simple_molecule
  simple_molecule dipeptide simple_molecule
  simple_molecule dipeptide_Ext simple_molecule
  simple_molecule diphosphate simple_molecule
  gene dmsABC gene
  RNA dmsABC_mRNA RNA
  simple_molecule ethanal simple_molecule
  simple_molecule ferri c-type cytochrome simple_molecule
  simple_molecule glyceraldehyde-P simple_molecule
  simple_molecule guanine simple_molecule
  simple_molecule guanosine simple_molecule
  simple_molecule guanosine-triphosphate simple_molecule
  gene hycABCDEFGHI gene
  RNA hycABCDEFGHI_mRNA RNA
  simple_molecule hydrogen simple_molecule
  simple_molecule hypoxanthine simple_molecule
  simple_molecule inosine simple_molecule
  simple_molecule large subunit of hydrogenase 3 simple_molecule
  simple_molecule menaquinol simple_molecule
  simple_molecule methionine simple_molecule
  gene moaABCDE gene
  RNA moaABCDE_mRNA RNA
  gene modABC gene
  RNA modABC_mRNA RNA
  simple_molecule molybdate simple_molecule
  simple_molecule molybdate_Ext simple_molecule
  gene napFDAGHBC-ccmABCDEFGH gene
  RNA napFDAGHBC-ccmABCDEFGH_mRNA RNA
  gene narXL gene
  RNA narXL_mRNA RNA
  simple_molecule nebularine simple_molecule
  simple_molecule nitrate simple_molecule
  simple_molecule nitrite simple_molecule
  simple_molecule oligopeptide simple_molecule
  simple_molecule oligopeptide_Ext simple_molecule
  gene oppABCDF gene
  RNA oppABCDF_mRNA RNA
  simple_molecule oxidized hydrogenase 3 simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule precursor of large subunit of hydrogenase 3 simple_molecule
  simple_molecule protoheme IX simple_molecule
  simple_molecule protoheme IX_Ext simple_molecule
  simple_molecule purine base simple_molecule
  simple_molecule reduced Cytochrome C protein simple_molecule
  simple_molecule reduced hydrogenase 3 simple_molecule
  simple_molecule ribose-1-phosphate simple_molecule
  simple_molecule ribose-5P simple_molecule
  simple_molecule thiocarboxylated small subunit of molybdopterin synthase simple_molecule
  simple_molecule thymidine simple_molecule
  simple_molecule thymine simple_molecule
  simple_molecule ubiquinol simple_molecule
  simple_molecule ubiquinone simple_molecule
  simple_molecule uracil simple_molecule
  simple_molecule vitamin K2 simple_molecule


Reactions       
Showing 93 reactions
molybdate + ModE ModE-molybdate
Name: molybdate + ModE -> ModE-molybdate
Description: Reaction transforming molybdate, ModE into ModE-molybdate
Type: state transition
Pathway Components: molybdate + ModE -> ModE-molybdate
Components:
Function Name Type
reactant ModE protein
product ModE-molybdate complex
reactant molybdate simple_molecule
ModE-molybdate hycABCDEFGHI hycABCDEFGHI_mRNA
Name: hycABCDEFGHI -> hycABCDEFGHI_mRNA
Description: Transcription of transcription unit hycABCDEFGHI. Reaction activation by ModE-molybdate.
Type: transcription
Pathway Components: hycABCDEFGHI - ModE-molybdate -> hycABCDEFGHI_mRNA
Components:
Function Name Type
activator ModE-molybdate complex
reactant hycABCDEFGHI gene
product hycABCDEFGHI_mRNA RNA
ModE-molybdate moaABCDE moaABCDE_mRNA
Name: moaABCDE -> moaABCDE_mRNA
Description: Transcription of transcription unit moaABCDE. Reaction activation by ModE-molybdate.
Type: transcription
Pathway Components: moaABCDE - ModE-molybdate -> moaABCDE_mRNA
Components:
Function Name Type
activator ModE-molybdate complex
reactant moaABCDE gene
product moaABCDE_mRNA RNA
ModE-molybdate napFDAGHBC-ccmABCDEFGH napFDAGHBC-ccmABCDEFGH_mRNA
Name: napFDAGHBC-ccmABCDEFGH -> napFDAGHBC-ccmABCDEFGH_mRNA
Description: Transcription of transcription unit napFDAGHBC-ccmABCDEFGH. Reaction activation by ModE-molybdate.
Type: transcription
Pathway Components: napFDAGHBC-ccmABCDEFGH - ModE-molybdate -> napFDAGHBC-ccmABCDEFGH_mRNA
Components:
Function Name Type
activator ModE-molybdate complex
reactant napFDAGHBC-ccmABCDEFGH gene
product napFDAGHBC-ccmABCDEFGH_mRNA RNA
ModE-molybdate narXL narXL_mRNA
Name: narXL -> narXL_mRNA
Description: Transcription of transcription unit narXL. Reaction activation by ModE-molybdate.
Type: transcription
Pathway Components: narXL - ModE-molybdate -> narXL_mRNA
Components:
Function Name Type
activator ModE-molybdate complex
reactant narXL gene
product narXL_mRNA RNA
ModE-molybdate deoCABD deoCABD_mRNA
Name: deoCABD -> deoCABD_mRNA
Description: Transcription of transcription unit deoCABD. Reaction inhibition by ModE-molybdate.
Type: transcription
Pathway Components: deoCABD - ModE-molybdate -> deoCABD_mRNA
Components:
Function Name Type
inhibitor ModE-molybdate complex
reactant deoCABD gene
product deoCABD_mRNA RNA
ModE-molybdate dmsABC dmsABC_mRNA
Name: dmsABC -> dmsABC_mRNA
Description: Transcription of transcription unit dmsABC. Reaction inhibition by ModE-molybdate.
Type: transcription
Pathway Components: dmsABC - ModE-molybdate -> dmsABC_mRNA
Components:
Function Name Type
inhibitor ModE-molybdate complex
reactant dmsABC gene
product dmsABC_mRNA RNA
ModE-molybdate modABC modABC_mRNA
Name: modABC -> modABC_mRNA
Description: Transcription of transcription unit modABC. Reaction inhibition by ModE-molybdate.
Type: transcription
Pathway Components: modABC - ModE-molybdate -> modABC_mRNA
Components:
Function Name Type
inhibitor ModE-molybdate complex
reactant modABC gene
product modABC_mRNA RNA
ModE-molybdate oppABCDF oppABCDF_mRNA
Name: oppABCDF -> oppABCDF_mRNA
Description: Transcription of transcription unit oppABCDF. Reaction inhibition by ModE-molybdate.
Type: transcription
Pathway Components: oppABCDF - ModE-molybdate -> oppABCDF_mRNA
Components:
Function Name Type
inhibitor ModE-molybdate complex
reactant oppABCDF gene
product oppABCDF_mRNA RNA
modABC_mRNA ModA
Name: modABC_mRNA -> ModA
Description: Translation of ModA
Type: translation
Pathway Components: modABC_mRNA -> ModA
Components:
Function Name Type
product ModA protein
reactant modABC_mRNA RNA
ModC + ModA + ModB ModC-ModB-ModA
Name: ModC + ModA + ModB -> ModC-ModB-ModA
Description: Reaction transforming ModC, ModA, ModB into ModC-ModB-ModA
Type: state transition
Pathway Components: ModC + ModA + ModB -> ModC-ModB-ModA
Components:
Function Name Type
reactant ModA protein
reactant ModB protein
reactant ModC protein
product ModC-ModB-ModA complex
ModC-ModB-ModA molybdate_Ext molybdate
Name: molybdate_Ext -> molybdate
Description: Transport of molybdate_Ext through a bacterial membrane, leading to the presence of molybdate inside the cell.
Type: transport
Pathway Components: molybdate_Ext - ModC-ModB-ModA -> molybdate
Components:
Function Name Type
catalyzer ModC-ModB-ModA complex
product molybdate simple_molecule
reactant molybdate_Ext simple_molecule
modABC_mRNA ModB
Name: modABC_mRNA -> ModB
Description: Translation of ModB
Type: translation
Pathway Components: modABC_mRNA -> ModB
Components:
Function Name Type
product ModB protein
reactant modABC_mRNA RNA
modABC_mRNA ModC
Name: modABC_mRNA -> ModC
Description: Translation of ModC
Type: translation
Pathway Components: modABC_mRNA -> ModC
Components:
Function Name Type
product ModC protein
reactant modABC_mRNA RNA
deoCABD_mRNA DeoC
Name: deoCABD_mRNA -> DeoC
Description: Translation of DeoC
Type: translation
Pathway Components: deoCABD_mRNA -> DeoC
Components:
Function Name Type
product DeoC protein
reactant deoCABD_mRNA RNA
DeoC 2-deoxy-D-ribose 5-phosphate glyceraldehyde-P + ethanal
Name: 2-deoxy-D-ribose 5-phosphate -> glyceraldehyde-P + ethanal
Description: Reaction transforming 2-deoxy-D-ribose 5-phosphate into glyceraldehyde-P, ethanal
Type: state transition
Pathway Components: 2-deoxy-D-ribose 5-phosphate - DeoC -> glyceraldehyde-P + ethanal
Components:
Function Name Type
reactant 2-deoxy-D-ribose 5-phosphate simple_molecule
catalyzer DeoC protein
product ethanal simple_molecule
product glyceraldehyde-P simple_molecule
deoCABD_mRNA DeoA
Name: deoCABD_mRNA -> DeoA
Description: Translation of DeoA
Type: translation
Pathway Components: deoCABD_mRNA -> DeoA
Components:
Function Name Type
product DeoA protein
reactant deoCABD_mRNA RNA
DeoA ribose-1-phosphate thymine thymidine + phosphate deoxy-D-ribose 1-phosphate + thymine
Name: thymidine + phosphate -> deoxy-D-ribose 1-phosphate + thymine
Description: Reaction transforming thymidine, phosphate into deoxy-D-ribose 1-phosphate, thymine
Type: state transition
Pathway Components: thymidine + phosphate - DeoA - ribose-1-phosphate - thymine -> deoxy-D-ribose 1-phosphate + thymine
Components:
Function Name Type
catalyzer DeoA protein
product deoxy-D-ribose 1-phosphate simple_molecule
reactant phosphate simple_molecule
inhibitor ribose-1-phosphate simple_molecule
reactant thymidine simple_molecule
inhibitor thymine simple_molecule
product thymine simple_molecule
DeoA deoxyuridine + phosphate deoxy-D-ribose 1-phosphate + uracil
Name: deoxyuridine + phosphate -> deoxy-D-ribose 1-phosphate + uracil
Description: Reaction transforming deoxyuridine, phosphate into deoxy-D-ribose 1-phosphate, uracil
Type: state transition
Pathway Components: deoxyuridine + phosphate - DeoA -> deoxy-D-ribose 1-phosphate + uracil
Components:
Function Name Type
catalyzer DeoA protein
product deoxy-D-ribose 1-phosphate simple_molecule
reactant deoxyuridine simple_molecule
reactant phosphate simple_molecule
product uracil simple_molecule
deoCABD_mRNA DeoB
Name: deoCABD_mRNA -> DeoB
Description: Translation of DeoB
Type: translation
Pathway Components: deoCABD_mRNA -> DeoB
Components:
Function Name Type
product DeoB protein
reactant deoCABD_mRNA RNA
DeoB deoxy-D-ribose 1-phosphate 2-deoxy-D-ribose 5-phosphate
Name: deoxy-D-ribose 1-phosphate -> 2-deoxy-D-ribose 5-phosphate
Description: Reaction transforming deoxy-D-ribose 1-phosphate into 2-deoxy-D-ribose 5-phosphate
Type: state transition
Pathway Components: deoxy-D-ribose 1-phosphate - DeoB -> 2-deoxy-D-ribose 5-phosphate
Components:
Function Name Type
product 2-deoxy-D-ribose 5-phosphate simple_molecule
catalyzer DeoB protein
reactant deoxy-D-ribose 1-phosphate simple_molecule
DeoB ribose-1-phosphate ribose-5P
Name: ribose-1-phosphate -> ribose-5P
Description: Reaction transforming ribose-1-phosphate into ribose-5P
Type: state transition
Pathway Components: ribose-1-phosphate - DeoB -> ribose-5P
Components:
Function Name Type
catalyzer DeoB protein
reactant ribose-1-phosphate simple_molecule
product ribose-5P simple_molecule
deoCABD_mRNA DeoD
Name: deoCABD_mRNA -> DeoD
Description: Translation of DeoD
Type: translation
Pathway Components: deoCABD_mRNA -> DeoD
Components:
Function Name Type
product DeoD protein
reactant deoCABD_mRNA RNA
DeoD nebularine + phosphate ribose-1-phosphate + purine base
Name: nebularine + phosphate -> ribose-1-phosphate + purine base
Description: Reaction transforming nebularine, phosphate into ribose-1-phosphate, purine base
Type: state transition
Pathway Components: nebularine + phosphate - DeoD -> ribose-1-phosphate + purine base
Components:
Function Name Type
catalyzer DeoD protein
reactant nebularine simple_molecule
reactant phosphate simple_molecule
product purine base simple_molecule
product ribose-1-phosphate simple_molecule
DeoD guanosine + phosphate ribose-1-phosphate + guanine
Name: guanosine + phosphate -> ribose-1-phosphate + guanine
Description: Reaction transforming guanosine, phosphate into ribose-1-phosphate, guanine
Type: state transition
Pathway Components: guanosine + phosphate - DeoD -> ribose-1-phosphate + guanine
Components:
Function Name Type
catalyzer DeoD protein
product guanine simple_molecule
reactant guanosine simple_molecule
reactant phosphate simple_molecule
product ribose-1-phosphate simple_molecule
DeoD adenosine deoxyguanosine + phosphate deoxy-D-ribose 1-phosphate + guanine
Name: deoxyguanosine + phosphate -> deoxy-D-ribose 1-phosphate + guanine
Description: Reaction transforming deoxyguanosine, phosphate into deoxy-D-ribose 1-phosphate, guanine
Type: state transition
Pathway Components: deoxyguanosine + phosphate - DeoD - adenosine -> deoxy-D-ribose 1-phosphate + guanine
Components:
Function Name Type
catalyzer DeoD protein
inhibitor adenosine simple_molecule
product deoxy-D-ribose 1-phosphate simple_molecule
reactant deoxyguanosine simple_molecule
product guanine simple_molecule
reactant phosphate simple_molecule
DeoD phosphate + inosine ribose-1-phosphate + hypoxanthine
Name: phosphate + inosine -> ribose-1-phosphate + hypoxanthine
Description: Reaction transforming phosphate, inosine into ribose-1-phosphate, hypoxanthine
Type: state transition
Pathway Components: phosphate + inosine - DeoD -> ribose-1-phosphate + hypoxanthine
Components:
Function Name Type
catalyzer DeoD protein
product hypoxanthine simple_molecule
reactant inosine simple_molecule
reactant phosphate simple_molecule
product ribose-1-phosphate simple_molecule
DeoD deoxyinosine + phosphate deoxy-D-ribose 1-phosphate + hypoxanthine
Name: deoxyinosine + phosphate -> deoxy-D-ribose 1-phosphate + hypoxanthine
Description: Reaction transforming deoxyinosine, phosphate into deoxy-D-ribose 1-phosphate, hypoxanthine
Type: state transition
Pathway Components: deoxyinosine + phosphate - DeoD -> deoxy-D-ribose 1-phosphate + hypoxanthine
Components:
Function Name Type
catalyzer DeoD protein
product deoxy-D-ribose 1-phosphate simple_molecule
reactant deoxyinosine simple_molecule
product hypoxanthine simple_molecule
reactant phosphate simple_molecule
DeoD adenosine + phosphate ribose-1-phosphate + adenine
Name: adenosine + phosphate -> ribose-1-phosphate + adenine
Description: Reaction transforming adenosine, phosphate into ribose-1-phosphate, adenine
Type: state transition
Pathway Components: adenosine + phosphate - DeoD -> ribose-1-phosphate + adenine
Components:
Function Name Type
catalyzer DeoD protein
product adenine simple_molecule
reactant adenosine simple_molecule
reactant phosphate simple_molecule
product ribose-1-phosphate simple_molecule
DeoD deoxyadenosine + phosphate deoxy-D-ribose 1-phosphate + adenine
Name: deoxyadenosine + phosphate -> deoxy-D-ribose 1-phosphate + adenine
Description: Reaction transforming deoxyadenosine, phosphate into deoxy-D-ribose 1-phosphate, adenine
Type: state transition
Pathway Components: deoxyadenosine + phosphate - DeoD -> deoxy-D-ribose 1-phosphate + adenine
Components:
Function Name Type
catalyzer DeoD protein
product adenine simple_molecule
product deoxy-D-ribose 1-phosphate simple_molecule
reactant deoxyadenosine simple_molecule
reactant phosphate simple_molecule
oppABCDF_mRNA OppA
Name: oppABCDF_mRNA -> OppA
Description: Translation of OppA
Type: translation
Pathway Components: oppABCDF_mRNA -> OppA
Components:
Function Name Type
product OppA protein
reactant oppABCDF_mRNA RNA
OppC + OppA + OppD + OppB + OppF OppC-OppD-OppF-OppB-OppA
Name: OppC + OppA + OppD + OppB + OppF -> OppC-OppD-OppF-OppB-OppA
Description: Reaction transforming OppC, OppA, OppD, OppB, OppF into OppC-OppD-OppF-OppB-OppA
Type: state transition
Pathway Components: OppC + OppA + OppD + OppB + OppF -> OppC-OppD-OppF-OppB-OppA
Components:
Function Name Type
reactant OppA protein
reactant OppB protein
reactant OppC protein
product OppC-OppD-OppF-OppB-OppA complex
reactant OppD protein
reactant OppF protein
OppC-OppD-OppF-OppB-OppA oligopeptide_Ext oligopeptide
Name: oligopeptide_Ext -> oligopeptide
Description: Transport of oligopeptide_Ext through a bacterial membrane, leading to the presence of oligopeptide inside the cell.
Type: transport
Pathway Components: oligopeptide_Ext - OppC-OppD-OppF-OppB-OppA -> oligopeptide
Components:
Function Name Type
catalyzer OppC-OppD-OppF-OppB-OppA complex
product oligopeptide simple_molecule
reactant oligopeptide_Ext simple_molecule
OppB-OppC-OppD-OppF-MppA OppC-OppD-OppF-OppB-OppA Ala-γ-D-Glu-Dap_Ext Ala-γ-D-Glu-Dap
Name: Ala-γ-D-Glu-Dap_Ext -> Ala-γ-D-Glu-Dap
Description: Transport of Ala-γ-D-Glu-Dap_Ext through a bacterial membrane, leading to the presence of Ala-γ-D-Glu-Dap inside the cell.
Type: transport
Pathway Components: Ala-γ-D-Glu-Dap_Ext - OppB-OppC-OppD-OppF-MppA - OppC-OppD-OppF-OppB-OppA -> Ala-γ-D-Glu-Dap
Components:
Function Name Type
product Ala-γ-D-Glu-Dap simple_molecule
reactant Ala-γ-D-Glu-Dap_Ext simple_molecule
catalyzer OppB-OppC-OppD-OppF-MppA complex
catalyzer OppC-OppD-OppF-OppB-OppA complex
OppC-OppD-OppF-OppB-OppA dipeptide_Ext dipeptide
Name: dipeptide_Ext -> dipeptide
Description: Transport of dipeptide_Ext through a bacterial membrane, leading to the presence of dipeptide inside the cell.
Type: transport
Pathway Components: dipeptide_Ext - OppC-OppD-OppF-OppB-OppA -> dipeptide
Components:
Function Name Type
catalyzer OppC-OppD-OppF-OppB-OppA complex
product dipeptide simple_molecule
reactant dipeptide_Ext simple_molecule
oppABCDF_mRNA OppB
Name: oppABCDF_mRNA -> OppB
Description: Translation of OppB
Type: translation
Pathway Components: oppABCDF_mRNA -> OppB
Components:
Function Name Type
product OppB protein
reactant oppABCDF_mRNA RNA
OppC + MppA + OppD + OppB + OppF OppB-OppC-OppD-OppF-MppA
Name: OppC + MppA + OppD + OppB + OppF -> OppB-OppC-OppD-OppF-MppA
Description: Reaction transforming OppC, MppA, OppD, OppB, OppF into OppB-OppC-OppD-OppF-MppA
Type: state transition
Pathway Components: OppC + MppA + OppD + OppB + OppF -> OppB-OppC-OppD-OppF-MppA
Components:
Function Name Type
reactant MppA protein
reactant OppB protein
product OppB-OppC-OppD-OppF-MppA complex
reactant OppC protein
reactant OppD protein
reactant OppF protein
oppABCDF_mRNA OppC
Name: oppABCDF_mRNA -> OppC
Description: Translation of OppC
Type: translation
Pathway Components: oppABCDF_mRNA -> OppC
Components:
Function Name Type
product OppC protein
reactant oppABCDF_mRNA RNA
oppABCDF_mRNA OppD
Name: oppABCDF_mRNA -> OppD
Description: Translation of OppD
Type: translation
Pathway Components: oppABCDF_mRNA -> OppD
Components:
Function Name Type
product OppD protein
reactant oppABCDF_mRNA RNA
oppABCDF_mRNA OppF
Name: oppABCDF_mRNA -> OppF
Description: Translation of OppF
Type: translation
Pathway Components: oppABCDF_mRNA -> OppF
Components:
Function Name Type
product OppF protein
reactant oppABCDF_mRNA RNA
moaABCDE_mRNA MoaA
Name: moaABCDE_mRNA -> MoaA
Description: Translation of MoaA
Type: translation
Pathway Components: moaABCDE_mRNA -> MoaA
Components:
Function Name Type
product MoaA protein
reactant moaABCDE_mRNA RNA
MoaA guanosine-triphosphate + A(H2) + SAM Products
Name: guanosine-triphosphate + A(H2) + SAM -> 5'-deoxyadenosine + 3',8-cH2GTP + methionine + acceptors
Description: Reaction transforming guanosine-triphosphate, A(H2), SAM into 5'-deoxyadenosine, 3',8-cH2GTP , methionine , acceptors
Type: state transition
Pathway Components: guanosine-triphosphate + A(H2) + SAM - MoaA -> 5'-deoxyadenosine + 3',8-cH2GTP + methionine + acceptors
Components:
Function Name Type
product 3',8-cH2GTP simple_molecule
product 5'-deoxyadenosine simple_molecule
reactant A(H2) simple_molecule
catalyzer MoaA protein
reactant SAM simple_molecule
product acceptors simple_molecule
reactant guanosine-triphosphate simple_molecule
product methionine simple_molecule
moaABCDE_mRNA MoaB
Name: moaABCDE_mRNA -> MoaB
Description: Translation of MoaB
Type: translation
Pathway Components: moaABCDE_mRNA -> MoaB
Components:
Function Name Type
product MoaB protein
reactant moaABCDE_mRNA RNA
moaABCDE_mRNA MoaC
Name: moaABCDE_mRNA -> MoaC
Description: Translation of MoaC
Type: translation
Pathway Components: moaABCDE_mRNA -> MoaC
Components:
Function Name Type
product MoaC protein
reactant moaABCDE_mRNA RNA
MoaC 3',8-cH2GTP diphosphate + cPMP
Name: 3',8-cH2GTP -> diphosphate + cPMP
Description: Reaction transforming 3',8-cH2GTP into diphosphate, cPMP
Type: state transition
Pathway Components: 3',8-cH2GTP - MoaC -> diphosphate + cPMP
Components:
Function Name Type
reactant 3',8-cH2GTP simple_molecule
catalyzer MoaC protein
product cPMP simple_molecule
product diphosphate simple_molecule
moaABCDE_mRNA MoaD
Name: moaABCDE_mRNA -> MoaD
Description: Translation of MoaD
Type: translation
Pathway Components: moaABCDE_mRNA -> MoaD
Components:
Function Name Type
product MoaD protein
reactant moaABCDE_mRNA RNA
MoaE + MoaD MoaD-MoaE
Name: MoaE + MoaD -> MoaD-MoaE
Description: Reaction transforming MoaE, MoaD into MoaD-MoaE
Type: state transition
Pathway Components: MoaE + MoaD -> MoaD-MoaE
Components:
Function Name Type
reactant MoaD protein
product MoaD-MoaE complex
reactant MoaE protein
MoaD-MoaE Reactants MPT-Synthase-small-subunits + H2Dtpp-mP
Name: thiocarboxylated small subunit of molybdopterin synthase + cPMP -> MPT-Synthase-small-subunits + H2Dtpp-mP
Description: Reaction transforming thiocarboxylated small subunit of molybdopterin synthase, cPMP into MPT-Synthase-small-subunits, H2Dtpp-mP
Type: state transition
Pathway Components: thiocarboxylated small subunit of molybdopterin synthase + cPMP - MoaD-MoaE -> MPT-Synthase-small-subunits + H2Dtpp-mP
Components:
Function Name Type
product H2Dtpp-mP simple_molecule
product MPT-Synthase-small-subunits simple_molecule
catalyzer MoaD-MoaE complex
reactant cPMP simple_molecule
reactant thiocarboxylated small subunit of molybdopterin synthase simple_molecule
moaABCDE_mRNA MoaE
Name: moaABCDE_mRNA -> MoaE
Description: Translation of MoaE
Type: translation
Pathway Components: moaABCDE_mRNA -> MoaE
Components:
Function Name Type
product MoaE protein
reactant moaABCDE_mRNA RNA
narXL_mRNA NarX
Name: narXL_mRNA -> NarX
Description: Translation of NarX
Type: translation
Pathway Components: narXL_mRNA -> NarX
Components:
Function Name Type
product NarX protein
reactant narXL_mRNA RNA
narXL_mRNA NarL
Name: narXL_mRNA -> NarL
Description: Translation of NarL
Type: translation
Pathway Components: narXL_mRNA -> NarL
Components:
Function Name Type
product NarL protein
reactant narXL_mRNA RNA
dmsABC_mRNA DmsA
Name: dmsABC_mRNA -> DmsA
Description: Translation of DmsA
Type: translation
Pathway Components: dmsABC_mRNA -> DmsA
Components:
Function Name Type
product DmsA protein
reactant dmsABC_mRNA RNA
DmsB + DmsC + DmsA DmsA-DmsB-DmsC
Name: DmsB + DmsC + DmsA -> DmsA-DmsB-DmsC
Description: Reaction transforming DmsB, DmsC, DmsA into DmsA-DmsB-DmsC
Type: state transition
Pathway Components: DmsB + DmsC + DmsA -> DmsA-DmsB-DmsC
Components:
Function Name Type
reactant DmsA protein
product DmsA-DmsB-DmsC complex
reactant DmsB protein
reactant DmsC protein
DmsA-DmsB-DmsC menaquinol + DMSO dimethylsulfide + vitamin K2
Name: menaquinol + DMSO -> dimethylsulfide + vitamin K2
Description: Reaction transforming menaquinol, DMSO into dimethylsulfide, vitamin K2
Type: state transition
Pathway Components: menaquinol + DMSO - DmsA-DmsB-DmsC -> dimethylsulfide + vitamin K2
Components:
Function Name Type
reactant DMSO simple_molecule
catalyzer DmsA-DmsB-DmsC complex
product dimethylsulfide simple_molecule
reactant menaquinol simple_molecule
product vitamin K2 simple_molecule
dmsABC_mRNA DmsB
Name: dmsABC_mRNA -> DmsB
Description: Translation of DmsB
Type: translation
Pathway Components: dmsABC_mRNA -> DmsB
Components:
Function Name Type
product DmsB protein
reactant dmsABC_mRNA RNA
dmsABC_mRNA DmsC
Name: dmsABC_mRNA -> DmsC
Description: Translation of DmsC
Type: translation
Pathway Components: dmsABC_mRNA -> DmsC
Components: