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Mlc Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
MalT HPr - phosphorylated_Ext N-acetyl-alpha-D-glucosamine 6-phosphate ptsHI-crr ManY ManX trehalose_Ext ManY manXYZ_mRNA ptsHI-crr_mRNA 2-deoxyglucose_Ext mlc_mRNA MtlR mlc-ynfK_mRNA 2-deoxy-D-glucose 6-phosphate ManX MurP MurNAc_Ext Crr EIIglc Methyl-D-glucoside_Ext chitosamine_Ext MtlR PtsG ManZ malT_mRNA Mlc ptsG seminose_Ext glucopyranose_Ext ptsG_mRNA manXYZ mlc methyl alpha-D-glucoside 6-phosphate alpha,alpha-trehalose 6-phosphate Crr EIIglc fructofuranose_Ext PtsG YnfK Mlc PtsH IIABMan malT ManNAc-6-P PtsG Crr alpha-D-glucosamine phosphate mannopyranose-6-P PtsI NAcGlc_Ext MurNAc-6-P keto-D-fructose 6-phosphate mlc-ynfK MurP glucose-6-P ManZ N-acetyl-beta-D-mannosamine_Ext TreB TreB Mlc Crr PtsH


Gensor Unit       
Name: Mlc
Classification:
Groups: Transcription
Carbohydrate transport and metabolism
Signal transduction mechanisms
Coenzyme transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0015764 - N-acetylglucosamine transport
GO:0009102 - biotin biosynthetic process
GO:0005975 - carbohydrate metabolic process
GO:0034219 - carbohydrate transmembrane transport
GO:0008643 - carbohydrate transport
GO:0032445 - fructose import
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0005886 - plasma membrane
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molecular_function GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0003824 - catalytic activity
GO:0004141 - dethiobiotin synthase activity
GO:0008047 - enzyme activator activity
GO:0005355 - glucose transmembrane transporter activity
GO:0042802 - identical protein binding
Read more >
Components:
  Function Name Type
  simple_molecule α,α-trehalose 6-phosphate simple_molecule
  simple_molecule α-D-glucosamine phosphate simple_molecule
  simple_molecule 2-deoxy-D-glucose 6-phosphate simple_molecule
  simple_molecule 2-deoxyglucose_Ext simple_molecule
  protein Crr protein
  simple_molecule EIIglc simple_molecule
  simple_molecule HPr - phosphorylated_Ext simple_molecule
  protein IIABMan protein
  protein MalT protein
  simple_molecule ManNAc-6-P simple_molecule
  protein ManX protein
  protein ManY protein
  protein ManZ protein
  complex ManZ-ManY-ManX complex
  simple_molecule Methyl-D-glucoside_Ext simple_molecule
  protein Mlc protein
  complex Mlc-EIIglc complex
  protein MtlR protein
  complex MtlR-PtsH complex
  simple_molecule MurNAc-6-P simple_molecule
  simple_molecule MurNAc_Ext simple_molecule
  protein MurP protein
  complex MurP-Crr complex
  simple_molecule N-acetyl-α-D-glucosamine 6-phosphate simple_molecule
  simple_molecule N-acetyl-beta-D-mannosamine_Ext simple_molecule
  simple_molecule NAcGlc_Ext simple_molecule
  protein PtsG protein
  complex PtsG-Crr complex
  complex PtsG-Mlc complex
  simple_molecule PtsH simple_molecule
  protein PtsI protein
  protein TreB protein
  complex TreB-Crr complex
  protein YnfK protein
  simple_molecule chitosamine_Ext simple_molecule
  simple_molecule fructofuranose_Ext simple_molecule
  simple_molecule glucopyranose_Ext simple_molecule
  simple_molecule glucose-6-P simple_molecule
  simple_molecule keto-D-fructose 6-phosphate simple_molecule
  gene malT gene
  RNA malT_mRNA RNA
  gene manXYZ gene
  RNA manXYZ_mRNA RNA
  simple_molecule mannopyranose-6-P simple_molecule
  simple_molecule methyl α-D-glucoside 6-phosphate simple_molecule
  gene mlc gene
  gene mlc-ynfK gene
  RNA mlc-ynfK_mRNA RNA
  RNA mlc_mRNA RNA
  gene ptsG gene
  RNA ptsG_mRNA RNA
  gene ptsHI-crr gene
  RNA ptsHI-crr_mRNA RNA
  simple_molecule seminose_Ext simple_molecule
  simple_molecule trehalose_Ext simple_molecule


Reactions       
Showing 35 reactions
Mlc malT malT_mRNA
Name: malT -> malT_mRNA
Description: Transcription of transcription unit malT. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: malT - Mlc -> malT_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant malT gene
product malT_mRNA RNA
Mlc manXYZ manXYZ_mRNA
Name: manXYZ -> manXYZ_mRNA
Description: Transcription of transcription unit manXYZ. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: manXYZ - Mlc -> manXYZ_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant manXYZ gene
product manXYZ_mRNA RNA
Mlc mlc mlc_mRNA
Name: mlc -> mlc_mRNA
Description: Transcription of transcription unit mlc. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc - Mlc -> mlc_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant mlc gene
product mlc_mRNA RNA
Mlc mlc-ynfK mlc-ynfK_mRNA
Name: mlc-ynfK -> mlc-ynfK_mRNA
Description: Transcription of transcription unit mlc-ynfK. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc-ynfK - Mlc -> mlc-ynfK_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant mlc-ynfK gene
product mlc-ynfK_mRNA RNA
Mlc ptsG ptsG_mRNA
Name: ptsG -> ptsG_mRNA
Description: Transcription of transcription unit ptsG. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsG - Mlc -> ptsG_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant ptsG gene
product ptsG_mRNA RNA
Mlc ptsHI-crr ptsHI-crr_mRNA
Name: ptsHI-crr -> ptsHI-crr_mRNA
Description: Transcription of transcription unit ptsHI-crr. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsHI-crr - Mlc -> ptsHI-crr_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant ptsHI-crr gene
product ptsHI-crr_mRNA RNA
EIIglc + Mlc Mlc-EIIglc
Name: EIIglc + Mlc -> Mlc-EIIglc
Description: Reaction transforming EIIglc, Mlc into Mlc-EIIglc
Type: state transition
Pathway Components: EIIglc + Mlc -> Mlc-EIIglc
Components:
Function Name Type
reactant EIIglc simple_molecule
reactant Mlc protein
product Mlc-EIIglc complex
mlc-ynfK_mRNA Mlc
Name: mlc-ynfK_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc-ynfK_mRNA -> Mlc
Components:
Function Name Type
product Mlc protein
reactant mlc-ynfK_mRNA RNA
PtsG + Mlc PtsG-Mlc
Name: PtsG + Mlc -> PtsG-Mlc
Description: Reaction transforming PtsG, Mlc into PtsG-Mlc
Type: state transition
Pathway Components: PtsG + Mlc -> PtsG-Mlc
Components:
Function Name Type
reactant Mlc protein
reactant PtsG protein
product PtsG-Mlc complex
mlc-ynfK_mRNA YnfK
Name: mlc-ynfK_mRNA -> YnfK
Description: Translation of YnfK
Type: translation
Pathway Components: mlc-ynfK_mRNA -> YnfK
Components:
Function Name Type
product YnfK protein
reactant mlc-ynfK_mRNA RNA
ptsG_mRNA PtsG
Name: ptsG_mRNA -> PtsG
Description: Translation of PtsG
Type: translation
Pathway Components: ptsG_mRNA -> PtsG
Components:
Function Name Type
product PtsG protein
reactant ptsG_mRNA RNA
PtsG + Crr PtsG-Crr
Name: PtsG + Crr -> PtsG-Crr
Description: Reaction transforming PtsG, Crr into PtsG-Crr
Type: state transition
Pathway Components: PtsG + Crr -> PtsG-Crr
Components:
Function Name Type
reactant Crr protein
reactant PtsG protein
product PtsG-Crr complex
ManZ-ManY-ManX PtsG-Crr HPr - phosphorylated_Ext + glucopyranose_Ext glucose-6-P + PtsH
Name: HPr - phosphorylated_Ext + glucopyranose_Ext -> glucose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, glucopyranose_Ext through a bacterial membrane, leading to the presence of glucose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + glucopyranose_Ext - ManZ-ManY-ManX - PtsG-Crr -> glucose-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
catalyzer PtsG-Crr complex
product PtsH simple_molecule
reactant glucopyranose_Ext simple_molecule
product glucose-6-P simple_molecule
PtsG-Crr HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext methyl α-D-glucoside 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext -> methyl α-D-glucoside 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, Methyl-D-glucoside_Ext through a bacterial membrane, leading to the presence of methyl α-D-glucoside 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext - PtsG-Crr -> methyl α-D-glucoside 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
reactant Methyl-D-glucoside_Ext simple_molecule
catalyzer PtsG-Crr complex
product PtsH simple_molecule
product methyl α-D-glucoside 6-phosphate simple_molecule
malT_mRNA MalT
Name: malT_mRNA -> MalT
Description: Translation of MalT
Type: translation
Pathway Components: malT_mRNA -> MalT
Components:
Function Name Type
product MalT protein
reactant malT_mRNA RNA
mlc_mRNA Mlc
Name: mlc_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc_mRNA -> Mlc
Components:
Function Name Type
product Mlc protein
reactant mlc_mRNA RNA
ptsHI-crr_mRNA PtsH
Name: ptsHI-crr_mRNA -> PtsH
Description: Translation of PtsH
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsH
Components:
Function Name Type
product PtsH simple_molecule
reactant ptsHI-crr_mRNA RNA
PtsH + MtlR MtlR-PtsH
Name: PtsH + MtlR -> MtlR-PtsH
Description: Reaction transforming PtsH, MtlR into MtlR-PtsH
Type: state transition
Pathway Components: PtsH + MtlR -> MtlR-PtsH
Components:
Function Name Type
reactant MtlR protein
product MtlR-PtsH complex
reactant PtsH simple_molecule
ptsHI-crr_mRNA PtsI
Name: ptsHI-crr_mRNA -> PtsI
Description: Translation of PtsI
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsI
Components:
Function Name Type
product PtsI protein
reactant ptsHI-crr_mRNA RNA
ptsHI-crr_mRNA Crr
Name: ptsHI-crr_mRNA -> Crr
Description: Translation of Crr
Type: translation
Pathway Components: ptsHI-crr_mRNA -> Crr
Components:
Function Name Type
product Crr protein
reactant ptsHI-crr_mRNA RNA
TreB + Crr TreB-Crr
Name: TreB + Crr -> TreB-Crr
Description: Reaction transforming TreB, Crr into TreB-Crr
Type: state transition
Pathway Components: TreB + Crr -> TreB-Crr
Components:
Function Name Type
reactant Crr protein
reactant TreB protein
product TreB-Crr complex
TreB-Crr HPr - phosphorylated_Ext + trehalose_Ext α,α-trehalose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + trehalose_Ext -> α,α-trehalose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, trehalose_Ext through a bacterial membrane, leading to the presence of α,α-trehalose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + trehalose_Ext - TreB-Crr -> α,α-trehalose 6-phosphate + PtsH
Components:
Function Name Type
product α,α-trehalose 6-phosphate simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
product PtsH simple_molecule
catalyzer TreB-Crr complex
reactant trehalose_Ext simple_molecule
MurP + Crr MurP-Crr
Name: MurP + Crr -> MurP-Crr
Description: Reaction transforming MurP, Crr into MurP-Crr
Type: state transition
Pathway Components: MurP + Crr -> MurP-Crr
Components:
Function Name Type
reactant Crr protein
reactant MurP protein
product MurP-Crr complex
MurP-Crr HPr - phosphorylated_Ext + MurNAc_Ext MurNAc-6-P + PtsH
Name: HPr - phosphorylated_Ext + MurNAc_Ext -> MurNAc-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, MurNAc_Ext through a bacterial membrane, leading to the presence of MurNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + MurNAc_Ext - MurP-Crr -> MurNAc-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
product MurNAc-6-P simple_molecule
reactant MurNAc_Ext simple_molecule
catalyzer MurP-Crr complex
product PtsH simple_molecule
manXYZ_mRNA ManX
Name: manXYZ_mRNA -> ManX
Description: Translation of ManX
Type: translation
Pathway Components: manXYZ_mRNA -> ManX
Components:
Function Name Type
product ManX protein
reactant manXYZ_mRNA RNA
ManX + ManY + ManZ ManZ-ManY-ManX
Name: ManX + ManY + ManZ -> ManZ-ManY-ManX
Description: Reaction transforming ManX, ManY, ManZ into ManZ-ManY-ManX
Type: state transition
Pathway Components: ManX + ManY + ManZ -> ManZ-ManY-ManX
Components:
Function Name Type
reactant ManX protein
reactant ManY protein
reactant ManZ protein
product ManZ-ManY-ManX complex
ManZ-ManY-ManX HPr - phosphorylated_Ext + seminose_Ext mannopyranose-6-P + PtsH
Name: HPr - phosphorylated_Ext + seminose_Ext -> mannopyranose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, seminose_Ext through a bacterial membrane, leading to the presence of mannopyranose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + seminose_Ext - ManZ-ManY-ManX -> mannopyranose-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
product mannopyranose-6-P simple_molecule
reactant seminose_Ext simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + 2-deoxyglucose_Ext 2-deoxy-D-glucose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext -> 2-deoxy-D-glucose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, 2-deoxyglucose_Ext through a bacterial membrane, leading to the presence of 2-deoxy-D-glucose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext - ManZ-ManY-ManX -> 2-deoxy-D-glucose 6-phosphate + PtsH
Components:
Function Name Type
product 2-deoxy-D-glucose 6-phosphate simple_molecule
reactant 2-deoxyglucose_Ext simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
ManZ-ManY-ManX Reactants ManNAc-6-P + PtsH
Name: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext -> ManNAc-6-P + PtsH
Description: Transport of N-acetyl-beta-D-mannosamine_Ext, HPr - phosphorylated_Ext through a bacterial membrane, leading to the presence of ManNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext - ManZ-ManY-ManX -> ManNAc-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
product ManNAc-6-P simple_molecule
catalyzer ManZ-ManY-ManX complex
reactant N-acetyl-beta-D-mannosamine_Ext simple_molecule
product PtsH simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + chitosamine_Ext α-D-glucosamine phosphate + PtsH
Name: HPr - phosphorylated_Ext + chitosamine_Ext -> α-D-glucosamine phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, chitosamine_Ext through a bacterial membrane, leading to the presence of α-D-glucosamine phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + chitosamine_Ext - ManZ-ManY-ManX -> α-D-glucosamine phosphate + PtsH
Components:
Function Name Type
product α-D-glucosamine phosphate simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
reactant chitosamine_Ext simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + NAcGlc_Ext N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + NAcGlc_Ext -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, NAcGlc_Ext through a bacterial membrane, leading to the presence of N-acetyl-α-D-glucosamine 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + NAcGlc_Ext - ManZ-ManY-ManX -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product N-acetyl-α-D-glucosamine 6-phosphate simple_molecule
reactant NAcGlc_Ext simple_molecule
product PtsH simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + fructofuranose_Ext keto-D-fructose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + fructofuranose_Ext -> keto-D-fructose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, fructofuranose_Ext through a bacterial membrane, leading to the presence of keto-D-fructose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + fructofuranose_Ext - ManZ-ManY-ManX -> keto-D-fructose 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
reactant fructofuranose_Ext simple_molecule
product keto-D-fructose 6-phosphate simple_molecule
manXYZ_mRNA IIABMan
Name: manXYZ_mRNA -> IIABMan
Description: Translation of IIABMan
Type: translation
Pathway Components: manXYZ_mRNA -> IIABMan
Components:
Function Name Type
product IIABMan protein
reactant manXYZ_mRNA RNA
manXYZ_mRNA ManY
Name: manXYZ_mRNA -> ManY
Description: Translation of ManY
Type: translation
Pathway Components: manXYZ_mRNA -> ManY
Components:
Function Name Type
product ManY protein
reactant manXYZ_mRNA RNA
manXYZ_mRNA ManZ
Name: manXYZ_mRNA -> ManZ
Description: Translation of ManZ
Type: translation
Pathway Components: manXYZ_mRNA -> ManZ
Components:
Function Name Type
product ManZ protein
reactant manXYZ_mRNA RNA
R1 R2 R3 R4 R5 R6 R7 R8 R9 R10 R11 R12 R13 R14 R15 R16 R17 R18 R19 R20 R21 R22 R23 R24 R25 R26 R27 R28 R29 R30 R31 R32 R33 R34 R35



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