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Mlc Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
MalT HPr - phosphorylated_Ext N-acetyl-alpha-D-glucosamine 6-phosphate ptsHI-crr ManY ManX trehalose_Ext ManY manXYZ_mRNA ptsHI-crr_mRNA 2-deoxyglucose_Ext mlc_mRNA MtlR This Gensor Unit is not yet available 2-deoxy-D-glucose 6-phosphate ManX MurP MurNAc_Ext Crr EIIglc Methyl-D-glucoside_Ext chitosamine_Ext MtlR PtsG ManZ malT_mRNA Mlc ptsG seminose_Ext glucopyranose_Ext ptsG_mRNA manXYZ mlc methyl alpha-D-glucoside 6-phosphate alpha,alpha-trehalose 6-phosphate Crr EIIglc fructofuranose_Ext PtsG YnfK Mlc PtsH IIABMan malT ManNAc-6-P PtsG Crr alpha-D-glucosamine phosphate mannopyranose-6-P PtsI NAcGlc_Ext MurNAc-6-P keto-D-fructose 6-phosphate This Gensor Unit is not yet available MurP glucose-6-P ManZ N-acetyl-beta-D-mannosamine_Ext TreB TreB Mlc Crr PtsH


Gensor Unit       
Name: Mlc
Classification:
Groups: Transcription
Carbohydrate transport and metabolism
Signal transduction mechanisms
Coenzyme transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0015764 - N-acetylglucosamine transport
GO:0009102 - biotin biosynthetic process
GO:0005975 - carbohydrate metabolic process
GO:0034219 - carbohydrate transmembrane transport
GO:0008643 - carbohydrate transport
GO:0032445 - fructose import
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031234 - extrinsic component of cytoplasmic side of plasma membrane
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0005886 - plasma membrane
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molecular_function GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0003824 - catalytic activity
GO:0004141 - dethiobiotin synthase activity
GO:0008047 - enzyme activator activity
GO:0005355 - glucose transmembrane transporter activity
GO:0042802 - identical protein binding
Read more >
Components:
  Function Name Type
  simple_molecule α,α-trehalose 6-phosphate simple_molecule
  simple_molecule α-D-glucosamine phosphate simple_molecule
  simple_molecule 2-deoxy-D-glucose 6-phosphate simple_molecule
  simple_molecule 2-deoxyglucose_Ext simple_molecule
  protein Crr protein
  simple_molecule EIIglc simple_molecule
  simple_molecule HPr - phosphorylated_Ext simple_molecule
  protein IIABMan protein
  protein MalT protein
  simple_molecule ManNAc-6-P simple_molecule
  protein ManX protein
  protein ManY protein
  protein ManZ protein
  complex ManZ-ManY-ManX complex
  simple_molecule Methyl-D-glucoside_Ext simple_molecule
  protein Mlc protein
  complex Mlc-EIIglc complex
  protein MtlR protein
  complex MtlR-PtsH complex
  simple_molecule MurNAc-6-P simple_molecule
  simple_molecule MurNAc_Ext simple_molecule
  protein MurP protein
  complex MurP-Crr complex
  simple_molecule N-acetyl-α-D-glucosamine 6-phosphate simple_molecule
  simple_molecule N-acetyl-beta-D-mannosamine_Ext simple_molecule
  simple_molecule NAcGlc_Ext simple_molecule
  protein PtsG protein
  complex PtsG-Crr complex
  complex PtsG-Mlc complex
  simple_molecule PtsH simple_molecule
  protein PtsI protein
  protein TreB protein
  complex TreB-Crr complex
  protein YnfK protein
  simple_molecule chitosamine_Ext simple_molecule
  simple_molecule fructofuranose_Ext simple_molecule
  simple_molecule glucopyranose_Ext simple_molecule
  simple_molecule glucose-6-P simple_molecule
  simple_molecule keto-D-fructose 6-phosphate simple_molecule
  gene malT gene
  RNA malT_mRNA RNA
  gene manXYZ gene
  RNA manXYZ_mRNA RNA
  simple_molecule mannopyranose-6-P simple_molecule
  simple_molecule methyl α-D-glucoside 6-phosphate simple_molecule
  gene mlc gene
  gene mlc-ynfK gene
  RNA mlc-ynfK_mRNA RNA
  RNA mlc_mRNA RNA
  gene ptsG gene
  RNA ptsG_mRNA RNA
  gene ptsHI-crr gene
  RNA ptsHI-crr_mRNA RNA
  simple_molecule seminose_Ext simple_molecule
  simple_molecule trehalose_Ext simple_molecule


Reactions       
Showing 35 reactions
Mlc malT malT_mRNA
Name: malT -> malT_mRNA
Description: Transcription of transcription unit malT. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: malT - Mlc -> malT_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant malT gene
product malT_mRNA RNA
Mlc manXYZ manXYZ_mRNA
Name: manXYZ -> manXYZ_mRNA
Description: Transcription of transcription unit manXYZ. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: manXYZ - Mlc -> manXYZ_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant manXYZ gene
product manXYZ_mRNA RNA
Mlc mlc mlc_mRNA
Name: mlc -> mlc_mRNA
Description: Transcription of transcription unit mlc. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc - Mlc -> mlc_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant mlc gene
product mlc_mRNA RNA
Mlc mlc-ynfK mlc-ynfK_mRNA
Name: mlc-ynfK -> mlc-ynfK_mRNA
Description: Transcription of transcription unit mlc-ynfK. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: mlc-ynfK - Mlc -> mlc-ynfK_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant mlc-ynfK gene
product mlc-ynfK_mRNA RNA
Mlc ptsG ptsG_mRNA
Name: ptsG -> ptsG_mRNA
Description: Transcription of transcription unit ptsG. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsG - Mlc -> ptsG_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant ptsG gene
product ptsG_mRNA RNA
Mlc ptsHI-crr ptsHI-crr_mRNA
Name: ptsHI-crr -> ptsHI-crr_mRNA
Description: Transcription of transcription unit ptsHI-crr. Reaction inhibition by Mlc.
Type: transcription
Pathway Components: ptsHI-crr - Mlc -> ptsHI-crr_mRNA
Components:
Function Name Type
inhibitor Mlc protein
reactant ptsHI-crr gene
product ptsHI-crr_mRNA RNA
EIIglc + Mlc Mlc-EIIglc
Name: EIIglc + Mlc -> Mlc-EIIglc
Description: Reaction transforming EIIglc, Mlc into Mlc-EIIglc
Type: state transition
Pathway Components: EIIglc + Mlc -> Mlc-EIIglc
Components:
Function Name Type
reactant EIIglc simple_molecule
reactant Mlc protein
product Mlc-EIIglc complex
mlc-ynfK_mRNA Mlc
Name: mlc-ynfK_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc-ynfK_mRNA -> Mlc
Components:
Function Name Type
product Mlc protein
reactant mlc-ynfK_mRNA RNA
PtsG + Mlc PtsG-Mlc
Name: PtsG + Mlc -> PtsG-Mlc
Description: Reaction transforming PtsG, Mlc into PtsG-Mlc
Type: state transition
Pathway Components: PtsG + Mlc -> PtsG-Mlc
Components:
Function Name Type
reactant Mlc protein
reactant PtsG protein
product PtsG-Mlc complex
mlc-ynfK_mRNA YnfK
Name: mlc-ynfK_mRNA -> YnfK
Description: Translation of YnfK
Type: translation
Pathway Components: mlc-ynfK_mRNA -> YnfK
Components:
Function Name Type
product YnfK protein
reactant mlc-ynfK_mRNA RNA
ptsG_mRNA PtsG
Name: ptsG_mRNA -> PtsG
Description: Translation of PtsG
Type: translation
Pathway Components: ptsG_mRNA -> PtsG
Components:
Function Name Type
product PtsG protein
reactant ptsG_mRNA RNA
PtsG + Crr PtsG-Crr
Name: PtsG + Crr -> PtsG-Crr
Description: Reaction transforming PtsG, Crr into PtsG-Crr
Type: state transition
Pathway Components: PtsG + Crr -> PtsG-Crr
Components:
Function Name Type
reactant Crr protein
reactant PtsG protein
product PtsG-Crr complex
ManZ-ManY-ManX PtsG-Crr HPr - phosphorylated_Ext + glucopyranose_Ext glucose-6-P + PtsH
Name: HPr - phosphorylated_Ext + glucopyranose_Ext -> glucose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, glucopyranose_Ext through a bacterial membrane, leading to the presence of glucose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + glucopyranose_Ext - ManZ-ManY-ManX - PtsG-Crr -> glucose-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
catalyzer PtsG-Crr complex
product PtsH simple_molecule
reactant glucopyranose_Ext simple_molecule
product glucose-6-P simple_molecule
PtsG-Crr HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext methyl α-D-glucoside 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext -> methyl α-D-glucoside 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, Methyl-D-glucoside_Ext through a bacterial membrane, leading to the presence of methyl α-D-glucoside 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + Methyl-D-glucoside_Ext - PtsG-Crr -> methyl α-D-glucoside 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
reactant Methyl-D-glucoside_Ext simple_molecule
catalyzer PtsG-Crr complex
product PtsH simple_molecule
product methyl α-D-glucoside 6-phosphate simple_molecule
malT_mRNA MalT
Name: malT_mRNA -> MalT
Description: Translation of MalT
Type: translation
Pathway Components: malT_mRNA -> MalT
Components:
Function Name Type
product MalT protein
reactant malT_mRNA RNA
mlc_mRNA Mlc
Name: mlc_mRNA -> Mlc
Description: Translation of Mlc
Type: translation
Pathway Components: mlc_mRNA -> Mlc
Components:
Function Name Type
product Mlc protein
reactant mlc_mRNA RNA
ptsHI-crr_mRNA PtsH
Name: ptsHI-crr_mRNA -> PtsH
Description: Translation of PtsH
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsH
Components:
Function Name Type
product PtsH simple_molecule
reactant ptsHI-crr_mRNA RNA
PtsH + MtlR MtlR-PtsH
Name: PtsH + MtlR -> MtlR-PtsH
Description: Reaction transforming PtsH, MtlR into MtlR-PtsH
Type: state transition
Pathway Components: PtsH + MtlR -> MtlR-PtsH
Components:
Function Name Type
reactant MtlR protein
product MtlR-PtsH complex
reactant PtsH simple_molecule
ptsHI-crr_mRNA PtsI
Name: ptsHI-crr_mRNA -> PtsI
Description: Translation of PtsI
Type: translation
Pathway Components: ptsHI-crr_mRNA -> PtsI
Components:
Function Name Type
product PtsI protein
reactant ptsHI-crr_mRNA RNA
ptsHI-crr_mRNA Crr
Name: ptsHI-crr_mRNA -> Crr
Description: Translation of Crr
Type: translation
Pathway Components: ptsHI-crr_mRNA -> Crr
Components:
Function Name Type
product Crr protein
reactant ptsHI-crr_mRNA RNA
TreB + Crr TreB-Crr
Name: TreB + Crr -> TreB-Crr
Description: Reaction transforming TreB, Crr into TreB-Crr
Type: state transition
Pathway Components: TreB + Crr -> TreB-Crr
Components:
Function Name Type
reactant Crr protein
reactant TreB protein
product TreB-Crr complex
TreB-Crr HPr - phosphorylated_Ext + trehalose_Ext α,α-trehalose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + trehalose_Ext -> α,α-trehalose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, trehalose_Ext through a bacterial membrane, leading to the presence of α,α-trehalose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + trehalose_Ext - TreB-Crr -> α,α-trehalose 6-phosphate + PtsH
Components:
Function Name Type
product α,α-trehalose 6-phosphate simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
product PtsH simple_molecule
catalyzer TreB-Crr complex
reactant trehalose_Ext simple_molecule
MurP + Crr MurP-Crr
Name: MurP + Crr -> MurP-Crr
Description: Reaction transforming MurP, Crr into MurP-Crr
Type: state transition
Pathway Components: MurP + Crr -> MurP-Crr
Components:
Function Name Type
reactant Crr protein
reactant MurP protein
product MurP-Crr complex
MurP-Crr HPr - phosphorylated_Ext + MurNAc_Ext MurNAc-6-P + PtsH
Name: HPr - phosphorylated_Ext + MurNAc_Ext -> MurNAc-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, MurNAc_Ext through a bacterial membrane, leading to the presence of MurNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + MurNAc_Ext - MurP-Crr -> MurNAc-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
product MurNAc-6-P simple_molecule
reactant MurNAc_Ext simple_molecule
catalyzer MurP-Crr complex
product PtsH simple_molecule
manXYZ_mRNA ManX
Name: manXYZ_mRNA -> ManX
Description: Translation of ManX
Type: translation
Pathway Components: manXYZ_mRNA -> ManX
Components:
Function Name Type
product ManX protein
reactant manXYZ_mRNA RNA
ManX + ManY + ManZ ManZ-ManY-ManX
Name: ManX + ManY + ManZ -> ManZ-ManY-ManX
Description: Reaction transforming ManX, ManY, ManZ into ManZ-ManY-ManX
Type: state transition
Pathway Components: ManX + ManY + ManZ -> ManZ-ManY-ManX
Components:
Function Name Type
reactant ManX protein
reactant ManY protein
reactant ManZ protein
product ManZ-ManY-ManX complex
ManZ-ManY-ManX HPr - phosphorylated_Ext + seminose_Ext mannopyranose-6-P + PtsH
Name: HPr - phosphorylated_Ext + seminose_Ext -> mannopyranose-6-P + PtsH
Description: Transport of HPr - phosphorylated_Ext, seminose_Ext through a bacterial membrane, leading to the presence of mannopyranose-6-P, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + seminose_Ext - ManZ-ManY-ManX -> mannopyranose-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
product mannopyranose-6-P simple_molecule
reactant seminose_Ext simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + 2-deoxyglucose_Ext 2-deoxy-D-glucose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext -> 2-deoxy-D-glucose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, 2-deoxyglucose_Ext through a bacterial membrane, leading to the presence of 2-deoxy-D-glucose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + 2-deoxyglucose_Ext - ManZ-ManY-ManX -> 2-deoxy-D-glucose 6-phosphate + PtsH
Components:
Function Name Type
product 2-deoxy-D-glucose 6-phosphate simple_molecule
reactant 2-deoxyglucose_Ext simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
ManZ-ManY-ManX Reactants ManNAc-6-P + PtsH
Name: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext -> ManNAc-6-P + PtsH
Description: Transport of N-acetyl-beta-D-mannosamine_Ext, HPr - phosphorylated_Ext through a bacterial membrane, leading to the presence of ManNAc-6-P, PtsH inside the cell.
Type: transport
Pathway Components: N-acetyl-beta-D-mannosamine_Ext + HPr - phosphorylated_Ext - ManZ-ManY-ManX -> ManNAc-6-P + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
product ManNAc-6-P simple_molecule
catalyzer ManZ-ManY-ManX complex
reactant N-acetyl-beta-D-mannosamine_Ext simple_molecule
product PtsH simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + chitosamine_Ext α-D-glucosamine phosphate + PtsH
Name: HPr - phosphorylated_Ext + chitosamine_Ext -> α-D-glucosamine phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, chitosamine_Ext through a bacterial membrane, leading to the presence of α-D-glucosamine phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + chitosamine_Ext - ManZ-ManY-ManX -> α-D-glucosamine phosphate + PtsH
Components:
Function Name Type
product α-D-glucosamine phosphate simple_molecule
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
reactant chitosamine_Ext simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + NAcGlc_Ext N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + NAcGlc_Ext -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, NAcGlc_Ext through a bacterial membrane, leading to the presence of N-acetyl-α-D-glucosamine 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + NAcGlc_Ext - ManZ-ManY-ManX -> N-acetyl-α-D-glucosamine 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product N-acetyl-α-D-glucosamine 6-phosphate simple_molecule
reactant NAcGlc_Ext simple_molecule
product PtsH simple_molecule
ManZ-ManY-ManX HPr - phosphorylated_Ext + fructofuranose_Ext keto-D-fructose 6-phosphate + PtsH
Name: HPr - phosphorylated_Ext + fructofuranose_Ext -> keto-D-fructose 6-phosphate + PtsH
Description: Transport of HPr - phosphorylated_Ext, fructofuranose_Ext through a bacterial membrane, leading to the presence of keto-D-fructose 6-phosphate, PtsH inside the cell.
Type: transport
Pathway Components: HPr - phosphorylated_Ext + fructofuranose_Ext - ManZ-ManY-ManX -> keto-D-fructose 6-phosphate + PtsH
Components:
Function Name Type
reactant HPr - phosphorylated_Ext simple_molecule
catalyzer ManZ-ManY-ManX complex
product PtsH simple_molecule
reactant fructofuranose_Ext simple_molecule
product keto-D-fructose 6-phosphate simple_molecule
manXYZ_mRNA IIABMan
Name: manXYZ_mRNA -> IIABMan
Description: Translation of IIABMan
Type: translation
Pathway Components: manXYZ_mRNA -> IIABMan
Components:
Function Name Type
product IIABMan protein
reactant manXYZ_mRNA RNA
manXYZ_mRNA ManY
Name: manXYZ_mRNA -> ManY
Description: Translation of ManY
Type: translation
Pathway Components: manXYZ_mRNA -> ManY
Components:
Function Name Type
product ManY protein
reactant manXYZ_mRNA RNA
manXYZ_mRNA ManZ
Name: manXYZ_mRNA -> ManZ
Description: Translation of ManZ
Type: translation
Pathway Components: manXYZ_mRNA -> ManZ
Components:
Function Name Type
product ManZ protein
reactant manXYZ_mRNA RNA



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