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MarR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
MarR paraquat benzoate sodium salicylate menadione MarR MarR plumbagin 2-HBA 2-HBA MarR MarA sodium salicylate MarR benzoate phenazine methosulfate MarR plumbagin paraquat marRAB MarB MarR MarR 2,4-DNP menadione phenazine methosulfate MarR 2,4-DNP marRAB_mRNA


Gensor Unit       
Name: MarR
Classification:
Groups: Transcription
Gene Ontology Terms (GO): biological_process GO:0071236 - cellular response to antibiotic
GO:0019249 - lactate biosynthetic process
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0045893 - positive regulation of transcription, DNA-templated
GO:0006355 - regulation of transcription, DNA-templated
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cellular_component GO:0005829 - cytosol
GO:0030288 - outer membrane-bounded periplasmic space
GO:0032993 - protein-DNA complex
GO:0032991 - protein-containing complex
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0000985 - bacterial-type RNA polymerase core promoter sequence-specific DNA binding
GO:0019172 - glyoxalase III activity
GO:0005515 - protein binding
GO:0042803 - protein homodimerization activity
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Components:
  Function Name Type
  simple_molecule 2,4-DNP simple_molecule
  simple_molecule 2-HBA simple_molecule
  protein MarA protein
  protein MarB protein
  protein MarR protein
  complex MarR-2,4-DNP complex
  complex MarR-2-HBA complex
  complex MarR-benzoate complex
  complex MarR-menadione complex
  complex MarR-paraquat complex
  complex MarR-phenazine methosulfate complex
  complex MarR-plumbagin complex
  complex MarR-sodium salicylate complex
  simple_molecule benzoate simple_molecule
  gene marRAB gene
  RNA marRAB_mRNA RNA
  simple_molecule menadione simple_molecule
  simple_molecule paraquat simple_molecule
  simple_molecule phenazine methosulfate simple_molecule
  simple_molecule plumbagin simple_molecule
  simple_molecule sodium salicylate simple_molecule


Reactions       
Showing 12 reactions
MarR marRAB marRAB_mRNA
Name: marRAB -> marRAB_mRNA
Description: Transcription of transcription unit marRAB. Reaction inhibition by MarR.
Type: transcription
Pathway Components: marRAB - MarR -> marRAB_mRNA
Components:
Function Name Type
inhibitor MarR protein
reactant marRAB gene
product marRAB_mRNA RNA
2,4-DNP + MarR MarR-2,4-DNP
Name: 2,4-DNP + MarR -> MarR-2,4-DNP
Description: Reaction transforming 2,4-DNP, MarR into MarR-2,4-DNP
Type: state transition
Pathway Components: 2,4-DNP + MarR -> MarR-2,4-DNP
Components:
Function Name Type
reactant 2,4-DNP simple_molecule
reactant MarR protein
product MarR-2,4-DNP complex
benzoate + MarR MarR-benzoate
Name: benzoate + MarR -> MarR-benzoate
Description: Reaction transforming benzoate, MarR into MarR-benzoate
Type: state transition
Pathway Components: benzoate + MarR -> MarR-benzoate
Components:
Function Name Type
reactant MarR protein
product MarR-benzoate complex
reactant benzoate simple_molecule
menadione + MarR MarR-menadione
Name: menadione + MarR -> MarR-menadione
Description: Reaction transforming menadione, MarR into MarR-menadione
Type: state transition
Pathway Components: menadione + MarR -> MarR-menadione
Components:
Function Name Type
reactant MarR protein
product MarR-menadione complex
reactant menadione simple_molecule
paraquat + MarR MarR-paraquat
Name: paraquat + MarR -> MarR-paraquat
Description: Reaction transforming paraquat, MarR into MarR-paraquat
Type: state transition
Pathway Components: paraquat + MarR -> MarR-paraquat
Components:
Function Name Type
reactant MarR protein
product MarR-paraquat complex
reactant paraquat simple_molecule
phenazine methosulfate + MarR MarR-phenazine methosulfate
Name: phenazine methosulfate + MarR -> MarR-phenazine methosulfate
Description: Reaction transforming phenazine methosulfate, MarR into MarR-phenazine methosulfate
Type: state transition
Pathway Components: phenazine methosulfate + MarR -> MarR-phenazine methosulfate
Components:
Function Name Type
reactant MarR protein
product MarR-phenazine methosulfate complex
reactant phenazine methosulfate simple_molecule
plumbagin + MarR MarR-plumbagin
Name: plumbagin + MarR -> MarR-plumbagin
Description: Reaction transforming plumbagin, MarR into MarR-plumbagin
Type: state transition
Pathway Components: plumbagin + MarR -> MarR-plumbagin
Components:
Function Name Type
reactant MarR protein
product MarR-plumbagin complex
reactant plumbagin simple_molecule
sodium salicylate + MarR MarR-sodium salicylate
Name: sodium salicylate + MarR -> MarR-sodium salicylate
Description: Reaction transforming sodium salicylate, MarR into MarR-sodium salicylate
Type: state transition
Pathway Components: sodium salicylate + MarR -> MarR-sodium salicylate
Components:
Function Name Type
reactant MarR protein
product MarR-sodium salicylate complex
reactant sodium salicylate simple_molecule
2-HBA + MarR MarR-2-HBA
Name: 2-HBA + MarR -> MarR-2-HBA
Description: Reaction transforming 2-HBA, MarR into MarR-2-HBA
Type: state transition
Pathway Components: 2-HBA + MarR -> MarR-2-HBA
Components:
Function Name Type
reactant 2-HBA simple_molecule
reactant MarR protein
product MarR-2-HBA complex
marRAB_mRNA MarR
Name: marRAB_mRNA -> MarR
Description: Translation of MarR
Type: translation
Pathway Components: marRAB_mRNA -> MarR
Components:
Function Name Type
product MarR protein
reactant marRAB_mRNA RNA
marRAB_mRNA MarA
Name: marRAB_mRNA -> MarA
Description: Translation of MarA
Type: translation
Pathway Components: marRAB_mRNA -> MarA
Components:
Function Name Type
product MarA protein
reactant marRAB_mRNA RNA
marRAB_mRNA MarB
Name: marRAB_mRNA -> MarB
Description: Translation of MarB
Type: translation
Pathway Components: marRAB_mRNA -> MarB
Components:
Function Name Type
product MarB protein
reactant marRAB_mRNA RNA
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