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MazE-MazF Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
MazE-MazF mazEFG dAMP xanthosine-5-P dITP MazF dTMP inosine triphosphate dTTP mazEFG_mRNA MazE cytidine-triphosphate 5'-UMP uridine-triphosphate dIMP MazG MazF dCMP dGMP 5'-IMP cytidylate dATP dCTP xanthosine 5' triphosphate dUMP diphosphate dUTP MazE dGTP nucleoside triphosphate mononucleotide diphosphate


Gensor Unit       
Name: MazE-MazF
Classification:
Groups: General function prediction only
Signal transduction mechanisms
Defense mechanisms
Gene Ontology Terms (GO): biological_process GO:0090502 - RNA phosphodiester bond hydrolysis, endonucleolytic
GO:0046047 - TTP catabolic process
GO:0046052 - UTP catabolic process
GO:0009267 - cellular response to starvation
GO:0046061 - dATP catabolic process
GO:0006203 - dGTP catabolic process
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cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0005524 - ATP binding
GO:0047693 - ATP diphosphatase activity
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003690 - double-stranded DNA binding
GO:0004519 - endonuclease activity
GO:0004521 - endoribonuclease activity
Read more >
Components:
  Function Name Type
  simple_molecule 5'-IMP simple_molecule
  simple_molecule 5'-UMP simple_molecule
  protein MazE protein
  protein MazE-MazF protein
  protein MazF protein
  complex MazF-MazE complex
  protein MazG protein
  simple_molecule cytidine-triphosphate simple_molecule
  simple_molecule cytidylate simple_molecule
  simple_molecule dAMP simple_molecule
  simple_molecule dATP simple_molecule
  simple_molecule dCMP simple_molecule
  simple_molecule dCTP simple_molecule
  simple_molecule dGMP simple_molecule
  simple_molecule dGTP simple_molecule
  simple_molecule dIMP simple_molecule
  simple_molecule dITP simple_molecule
  simple_molecule dTMP simple_molecule
  simple_molecule dTTP simple_molecule
  simple_molecule dUMP simple_molecule
  simple_molecule dUTP simple_molecule
  simple_molecule diphosphate simple_molecule
  simple_molecule inosine triphosphate simple_molecule
  gene mazEFG gene
  RNA mazEFG_mRNA RNA
  simple_molecule mononucleotide simple_molecule
  simple_molecule nucleoside triphosphate simple_molecule
  simple_molecule uridine-triphosphate simple_molecule
  simple_molecule xanthosine 5' triphosphate simple_molecule
  simple_molecule xanthosine-5-P simple_molecule


Reactions       
Showing 16 reactions
MazE-MazF mazEFG mazEFG_mRNA
Name: mazEFG -> mazEFG_mRNA
Description: Transcription of transcription unit mazEFG. Reaction inhibition by MazE-MazF.
Type: transcription
Pathway Components: mazEFG - MazE-MazF -> mazEFG_mRNA
Components:
Function Name Type
inhibitor MazE-MazF protein
reactant mazEFG gene
product mazEFG_mRNA RNA
mazEFG_mRNA MazE
Name: mazEFG_mRNA -> MazE
Description: Translation of MazE
Type: translation
Pathway Components: mazEFG_mRNA -> MazE
Components:
Function Name Type
product MazE protein
reactant mazEFG_mRNA RNA
MazE + MazF MazF-MazE
Name: MazE + MazF -> MazF-MazE
Description: Reaction transforming MazE, MazF into MazF-MazE
Type: state transition
Pathway Components: MazE + MazF -> MazF-MazE
Components:
Function Name Type
reactant MazE protein
reactant MazF protein
product MazF-MazE complex
mazEFG_mRNA MazF
Name: mazEFG_mRNA -> MazF
Description: Translation of MazF
Type: translation
Pathway Components: mazEFG_mRNA -> MazF
Components:
Function Name Type
product MazF protein
reactant mazEFG_mRNA RNA
mazEFG_mRNA MazG
Name: mazEFG_mRNA -> MazG
Description: Translation of MazG
Type: translation
Pathway Components: mazEFG_mRNA -> MazG
Components:
Function Name Type
product MazG protein
reactant mazEFG_mRNA RNA
MazG nucleoside triphosphate mononucleotide + diphosphate
Name: nucleoside triphosphate -> mononucleotide + diphosphate
Description: Reaction transforming nucleoside triphosphate into mononucleotide, diphosphate
Type: state transition
Pathway Components: nucleoside triphosphate - MazG -> mononucleotide + diphosphate
Components:
Function Name Type
catalyzer MazG protein
product diphosphate simple_molecule
product mononucleotide simple_molecule
reactant nucleoside triphosphate simple_molecule
MazG dCTP diphosphate + dCMP
Name: dCTP -> diphosphate + dCMP
Description: Reaction transforming dCTP into diphosphate, dCMP
Type: state transition
Pathway Components: dCTP - MazG -> diphosphate + dCMP
Components:
Function Name Type
catalyzer MazG protein
product dCMP simple_molecule
reactant dCTP simple_molecule
product diphosphate simple_molecule
MazG dUTP diphosphate + dUMP
Name: dUTP -> diphosphate + dUMP
Description: Reaction transforming dUTP into diphosphate, dUMP
Type: state transition
Pathway Components: dUTP - MazG -> diphosphate + dUMP
Components:
Function Name Type
catalyzer MazG protein
product dUMP simple_molecule
reactant dUTP simple_molecule
product diphosphate simple_molecule
MazG dAMP dATP diphosphate + dAMP
Name: dATP -> diphosphate + dAMP
Description: Reaction transforming dATP into diphosphate, dAMP
Type: state transition
Pathway Components: dATP - MazG - dAMP -> diphosphate + dAMP
Components:
Function Name Type
catalyzer MazG protein
inhibitor dAMP simple_molecule
product dAMP simple_molecule
reactant dATP simple_molecule
product diphosphate simple_molecule
MazG inosine triphosphate diphosphate + 5'-IMP
Name: inosine triphosphate -> diphosphate + 5'-IMP
Description: Reaction transforming inosine triphosphate into diphosphate, 5'-IMP
Type: state transition
Pathway Components: inosine triphosphate - MazG -> diphosphate + 5'-IMP
Components:
Function Name Type
product 5'-IMP simple_molecule
catalyzer MazG protein
product diphosphate simple_molecule
reactant inosine triphosphate simple_molecule
MazG xanthosine 5' triphosphate xanthosine-5-P + diphosphate
Name: xanthosine 5' triphosphate -> xanthosine-5-P + diphosphate
Description: Reaction transforming xanthosine 5' triphosphate into xanthosine-5-P, diphosphate
Type: state transition
Pathway Components: xanthosine 5' triphosphate - MazG -> xanthosine-5-P + diphosphate
Components:
Function Name Type
catalyzer MazG protein
product diphosphate simple_molecule
reactant xanthosine 5' triphosphate simple_molecule
product xanthosine-5-P simple_molecule
MazG dTTP diphosphate + dTMP
Name: dTTP -> diphosphate + dTMP
Description: Reaction transforming dTTP into diphosphate, dTMP
Type: state transition
Pathway Components: dTTP - MazG -> diphosphate + dTMP
Components:
Function Name Type
catalyzer MazG protein
product dTMP simple_molecule
reactant dTTP simple_molecule
product diphosphate simple_molecule
MazG dGTP diphosphate + dGMP
Name: dGTP -> diphosphate + dGMP
Description: Reaction transforming dGTP into diphosphate, dGMP
Type: state transition
Pathway Components: dGTP - MazG -> diphosphate + dGMP
Components:
Function Name Type
catalyzer MazG protein
product dGMP simple_molecule
reactant dGTP simple_molecule
product diphosphate simple_molecule
MazG cytidine-triphosphate diphosphate + cytidylate
Name: cytidine-triphosphate -> diphosphate + cytidylate
Description: Reaction transforming cytidine-triphosphate into diphosphate, cytidylate
Type: state transition
Pathway Components: cytidine-triphosphate - MazG -> diphosphate + cytidylate
Components:
Function Name Type
catalyzer MazG protein
reactant cytidine-triphosphate simple_molecule
product cytidylate simple_molecule
product diphosphate simple_molecule
MazG uridine-triphosphate diphosphate + 5'-UMP
Name: uridine-triphosphate -> diphosphate + 5'-UMP
Description: Reaction transforming uridine-triphosphate into diphosphate, 5'-UMP
Type: state transition
Pathway Components: uridine-triphosphate - MazG -> diphosphate + 5'-UMP
Components:
Function Name Type
product 5'-UMP simple_molecule
catalyzer MazG protein
product diphosphate simple_molecule
reactant uridine-triphosphate simple_molecule
MazG dITP diphosphate + dIMP
Name: dITP -> diphosphate + dIMP
Description: Reaction transforming dITP into diphosphate, dIMP
Type: state transition
Pathway Components: dITP - MazG -> diphosphate + dIMP
Components:
Function Name Type
catalyzer MazG protein
product dIMP simple_molecule
reactant dITP simple_molecule
product diphosphate simple_molecule
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