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IlvY Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
ketopantoate IlvY pantoate IlvY alpha-acetohydroxybutirate IlvY alpha-acetolactate (R)-2,3-dihydroxy-3-methylvalerate alpha-acetolactate ilvC IlvC ilvY ilvC_mRNA (S)-2-aceto-2-hydroxybutanoate alpha-acetohydroxybutirate (R)-2,3-dihydroxy-isovalerate ilvY_mRNA


Gensor Unit       
Name: IlvY
Classification:
Groups: Transcription
Amino acid transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0009082 - branched-chain amino acid biosynthetic process
GO:0008652 - cellular amino acid biosynthetic process
GO:0009097 - isoleucine biosynthetic process
GO:0051289 - protein homotetramerization
GO:0006355 - regulation of transcription, DNA-templated
GO:0006351 - transcription, DNA-templated
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0050661 - NADP binding
GO:0042802 - identical protein binding
GO:0004455 - ketol-acid reductoisomerase activity
GO:0000287 - magnesium ion binding
GO:0046872 - metal ion binding
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Components:
  Function Name Type
  simple_molecule α-acetohydroxybutirate simple_molecule
  simple_molecule α-acetolactate simple_molecule
  simple_molecule (R)-2,3-dihydroxy-3-methylvalerate simple_molecule
  simple_molecule (R)-2,3-dihydroxy-isovalerate simple_molecule
  simple_molecule (S)-2-aceto-2-hydroxybutanoate simple_molecule
  protein IlvC protein
  protein IlvY protein
  complex IlvY-α-acetohydroxybutirate complex
  complex IlvY-α-acetolactate complex
  gene ilvC gene
  RNA ilvC_mRNA RNA
  gene ilvY gene
  RNA ilvY_mRNA RNA
  simple_molecule ketopantoate simple_molecule
  simple_molecule pantoate simple_molecule


Reactions       
Showing 9 reactions
IlvY ilvY ilvY_mRNA
Name: ilvY -> ilvY_mRNA
Description: Transcription of transcription unit ilvY. Reaction inhibition by IlvY.
Type: transcription
Pathway Components: ilvY - IlvY -> ilvY_mRNA
Components:
Function Name Type
inhibitor IlvY protein
reactant ilvY gene
product ilvY_mRNA RNA
α-acetolactate + IlvY IlvY-α-acetolactate
Name: α-acetolactate + IlvY -> IlvY-α-acetolactate
Description: Reaction transforming α-acetolactate, IlvY into IlvY-α-acetolactate
Type: state transition
Pathway Components: α-acetolactate + IlvY -> IlvY-α-acetolactate
Components:
Function Name Type
reactant α-acetolactate simple_molecule
reactant IlvY protein
product IlvY-α-acetolactate complex
IlvY-α-acetolactate ilvC ilvC_mRNA
Name: ilvC -> ilvC_mRNA
Description: Transcription of transcription unit ilvC. Reaction activation by IlvY-α-acetolactate.
Type: transcription
Pathway Components: ilvC - IlvY-α-acetolactate -> ilvC_mRNA
Components:
Function Name Type
activator IlvY-α-acetolactate complex
reactant ilvC gene
product ilvC_mRNA RNA
α-acetohydroxybutirate + IlvY IlvY-α-acetohydroxybutirate
Name: α-acetohydroxybutirate + IlvY -> IlvY-α-acetohydroxybutirate
Description: Reaction transforming α-acetohydroxybutirate, IlvY into IlvY-α-acetohydroxybutirate
Type: state transition
Pathway Components: α-acetohydroxybutirate + IlvY -> IlvY-α-acetohydroxybutirate
Components:
Function Name Type
reactant α-acetohydroxybutirate simple_molecule
reactant IlvY protein
product IlvY-α-acetohydroxybutirate complex
ilvY_mRNA IlvY
Name: ilvY_mRNA -> IlvY
Description: Translation of IlvY
Type: translation
Pathway Components: ilvY_mRNA -> IlvY
Components:
Function Name Type
product IlvY protein
reactant ilvY_mRNA RNA
ilvC_mRNA IlvC
Name: ilvC_mRNA -> IlvC
Description: Translation of IlvC
Type: translation
Pathway Components: ilvC_mRNA -> IlvC
Components:
Function Name Type
product IlvC protein
reactant ilvC_mRNA RNA
IlvC α-acetolactate (R)-2,3-dihydroxy-isovalerate
Name: α-acetolactate -> (R)-2,3-dihydroxy-isovalerate
Description: Reaction transforming α-acetolactate into (R)-2,3-dihydroxy-isovalerate
Type: state transition
Pathway Components: α-acetolactate - IlvC -> (R)-2,3-dihydroxy-isovalerate
Components:
Function Name Type
reactant α-acetolactate simple_molecule
product (R)-2,3-dihydroxy-isovalerate simple_molecule
catalyzer IlvC protein
IlvC (S)-2-aceto-2-hydroxybutanoate (R)-2,3-dihydroxy-3-methylvalerate
Name: (S)-2-aceto-2-hydroxybutanoate -> (R)-2,3-dihydroxy-3-methylvalerate
Description: Reaction transforming (S)-2-aceto-2-hydroxybutanoate into (R)-2,3-dihydroxy-3-methylvalerate
Type: state transition
Pathway Components: (S)-2-aceto-2-hydroxybutanoate - IlvC -> (R)-2,3-dihydroxy-3-methylvalerate
Components:
Function Name Type
product (R)-2,3-dihydroxy-3-methylvalerate simple_molecule
reactant (S)-2-aceto-2-hydroxybutanoate simple_molecule
catalyzer IlvC protein
IlvC pantoate ketopantoate pantoate
Name: ketopantoate -> pantoate
Description: Reaction transforming ketopantoate into pantoate
Type: state transition
Pathway Components: ketopantoate - IlvC - pantoate -> pantoate
Components:
Function Name Type
catalyzer IlvC protein
reactant ketopantoate simple_molecule
inhibitor pantoate simple_molecule
product pantoate simple_molecule



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