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GadW Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
gadBC_mRNA gadY HdeA MdtE This Gensor Unit is not yet available MdtF gadEF-mdtEF GadC DctR GadA slp-dctR MdtF gadAX_mRNA This Gensor Unit is not yet available RNA:GadF YhiD GadB gadY_mRNA L-glutamate_Ext RcsB This Gensor Unit is not yet available gadBC GadE Slp This Gensor Unit is not yet available drug_Ext drug slp-dctR_mRNA TolC gadEF-mdtEF_mRNA hdeAB-yhiD_mRNA CO2 GABA_Ext GadX MdtE RNA:IS183 GadW hdeAB-yhiD GadE L-glutamate RcsB This Gensor Unit is not yet available TolC This Gensor Unit is not yet available GABA gadAX HdeB


Gensor Unit       
Name: GadW
Classification:
Groups: Transcription
Signal transduction mechanisms
Amino acid transport and metabolism
Defense mechanisms
Cell wall/membrane/envelope biogenesis
Gene Ontology Terms (GO): biological_process GO:1902475 - L-alpha-amino acid transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:0001121 - bacterial transcription
GO:0015721 - bile acid and bile salt transport
GO:0019752 - carboxylic acid metabolic process
Read more >
cellular_component GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0031226 - intrinsic component of plasma membrane
GO:0016020 - membrane
Read more >
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0015179 - L-amino acid transmembrane transporter activity
GO:0015171 - amino acid transmembrane transporter activity
GO:0015297 - antiporter activity
GO:0000986 - bacterial-type cis-regulatory region sequence-specific DNA binding
GO:0016831 - carboxy-lyase activity
Read more >
Components:
  Function Name Type
  simple_molecule CO2 simple_molecule
  protein DctR protein
  simple_molecule GABA simple_molecule
  simple_molecule GABA_Ext simple_molecule
  protein GadA protein
  protein GadB protein
  protein GadC protein
  protein GadE protein
  protein GadW protein
  protein GadX protein
  protein HdeA protein
  protein HdeB protein
  simple_molecule L-glutamate simple_molecule
  simple_molecule L-glutamate_Ext simple_molecule
  protein MdtE protein
  protein MdtF protein
  protein RNA:GadF protein
  protein RNA:IS183 protein
  protein RcsB protein
  complex RcsB-GadE complex
  protein Slp protein
  protein TolC protein
  complex TolC-MdtE-MdtF complex
  protein YhiD protein
  simple_molecule drug simple_molecule
  simple_molecule drug_Ext simple_molecule
  gene gadAX gene
  RNA gadAX_mRNA RNA
  gene gadBC gene
  RNA gadBC_mRNA RNA
  gene gadEF-mdtEF gene
  RNA gadEF-mdtEF_mRNA RNA
  gene gadW gene
  RNA gadW_mRNA RNA
  gene gadX gene
  gene gadXW gene
  RNA gadXW_mRNA RNA
  RNA gadX_mRNA RNA
  gene gadY gene
  RNA gadY_mRNA RNA
  gene hdeAB-yhiD gene
  RNA hdeAB-yhiD_mRNA RNA
  gene slp-dctR gene
  RNA slp-dctR_mRNA RNA


Reactions       
Showing 32 reactions
GadW gadEF-mdtEF gadEF-mdtEF_mRNA
Name: gadEF-mdtEF -> gadEF-mdtEF_mRNA
Description: Transcription of transcription unit gadEF-mdtEF. Reaction activation by GadW.
Type: transcription
Pathway Components: gadEF-mdtEF - GadW -> gadEF-mdtEF_mRNA
Components:
Function Name Type
activator GadW protein
reactant gadEF-mdtEF gene
product gadEF-mdtEF_mRNA RNA
GadW GadW gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadAX - GadW - GadW -> gadAX_mRNA
Components:
Function Name Type
activator GadW protein
inhibitor GadW protein
reactant gadAX gene
product gadAX_mRNA RNA
GadW GadW gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadBC - GadW - GadW -> gadBC_mRNA
Components:
Function Name Type
activator GadW protein
inhibitor GadW protein
reactant gadBC gene
product gadBC_mRNA RNA
GadW GadW hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction activation by GadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: hdeAB-yhiD - GadW - GadW -> hdeAB-yhiD_mRNA
Components:
Function Name Type
activator GadW protein
inhibitor GadW protein
reactant hdeAB-yhiD gene
product hdeAB-yhiD_mRNA RNA
GadW gadW gadW_mRNA
Name: gadW -> gadW_mRNA
Description: Transcription of transcription unit gadW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadW - GadW -> gadW_mRNA
Components:
Function Name Type
inhibitor GadW protein
reactant gadW gene
product gadW_mRNA RNA
GadW gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadX - GadW -> gadX_mRNA
Components:
Function Name Type
inhibitor GadW protein
reactant gadX gene
product gadX_mRNA RNA
GadW gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadXW - GadW -> gadXW_mRNA
Components:
Function Name Type
inhibitor GadW protein
reactant gadXW gene
product gadXW_mRNA RNA
GadW gadY gadY_mRNA
Name: gadY -> gadY_mRNA
Description: Transcription of transcription unit gadY. Reaction inhibition by GadW.
Type: transcription
Pathway Components: gadY - GadW -> gadY_mRNA
Components:
Function Name Type
inhibitor GadW protein
reactant gadY gene
product gadY_mRNA RNA
GadW slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR. Reaction inhibition by GadW.
Type: transcription
Pathway Components: slp-dctR - GadW -> slp-dctR_mRNA
Components:
Function Name Type
inhibitor GadW protein
reactant slp-dctR gene
product slp-dctR_mRNA RNA
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Pathway Components: slp-dctR_mRNA -> Slp
Components:
Function Name Type
product Slp protein
reactant slp-dctR_mRNA RNA
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Pathway Components: slp-dctR_mRNA -> DctR
Components:
Function Name Type
product DctR protein
reactant slp-dctR_mRNA RNA
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Pathway Components: gadBC_mRNA -> GadB
Components:
Function Name Type
product GadB protein
reactant gadBC_mRNA RNA
GadA GadB L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA - GadB -> GABA + CO2
Components:
Function Name Type
product CO2 simple_molecule
product GABA simple_molecule
catalyzer GadA protein
catalyzer GadB protein
reactant L-glutamate simple_molecule
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Pathway Components: gadBC_mRNA -> GadC
Components:
Function Name Type
product GadC protein
reactant gadBC_mRNA RNA
GadC L-glutamate_Ext + GABA_Ext L-glutamate + GABA
Name: L-glutamate_Ext + GABA_Ext -> L-glutamate + GABA
Description: Transport of L-glutamate_Ext, GABA_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the cell.
Type: transport
Pathway Components: L-glutamate_Ext + GABA_Ext - GadC -> L-glutamate + GABA
Components:
Function Name Type
product GABA simple_molecule
reactant GABA_Ext simple_molecule
catalyzer GadC protein
product L-glutamate simple_molecule
reactant L-glutamate_Ext simple_molecule
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type
product GadA protein
reactant gadAX_mRNA RNA
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadAX_mRNA RNA
gadX_mRNA GadX
Name: gadX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadX_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadX_mRNA RNA
gadW_mRNA GadW
Name: gadW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadW_mRNA -> GadW
Components:
Function Name Type
product GadW protein
reactant gadW_mRNA RNA
gadY_mRNA RNA:IS183
Name: gadY_mRNA -> RNA:IS183
Description: Translation of RNA:IS183
Type: translation
Pathway Components: gadY_mRNA -> RNA:IS183
Components:
Function Name Type
product RNA:IS183 protein
reactant gadY_mRNA RNA
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type
product HdeA protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type
product HdeB protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type
product YhiD protein
reactant hdeAB-yhiD_mRNA RNA
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadXW_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadXW_mRNA RNA
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadXW_mRNA -> GadW
Components:
Function Name Type
product GadW protein
reactant gadXW_mRNA RNA
gadEF-mdtEF_mRNA GadE
Name: gadEF-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> GadE
Components:
Function Name Type
product GadE protein
reactant gadEF-mdtEF_mRNA RNA
RcsB + GadE RcsB-GadE
Name: RcsB + GadE -> RcsB-GadE
Description: Reaction transforming RcsB, GadE into RcsB-GadE
Type: state transition
Pathway Components: RcsB + GadE -> RcsB-GadE
Components:
Function Name Type
reactant GadE protein
reactant RcsB protein
product RcsB-GadE complex
gadEF-mdtEF_mRNA RNA:GadF
Name: gadEF-mdtEF_mRNA -> RNA:GadF
Description: Translation of RNA:GadF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> RNA:GadF
Components:
Function Name Type
product RNA:GadF protein
reactant gadEF-mdtEF_mRNA RNA
gadEF-mdtEF_mRNA MdtE
Name: gadEF-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtE
Components:
Function Name Type
product MdtE protein
reactant gadEF-mdtEF_mRNA RNA
MdtE + MdtF + TolC TolC-MdtE-MdtF
Name: MdtE + MdtF + TolC -> TolC-MdtE-MdtF
Description: Reaction transforming MdtE, MdtF, TolC into TolC-MdtE-MdtF
Type: state transition
Pathway Components: MdtE + MdtF + TolC -> TolC-MdtE-MdtF
Components:
Function Name Type
reactant MdtE protein
reactant MdtF protein
reactant TolC protein
product TolC-MdtE-MdtF complex
TolC-MdtE-MdtF drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - TolC-MdtE-MdtF -> drug
Components:
Function Name Type
catalyzer TolC-MdtE-MdtF complex
product drug simple_molecule
reactant drug_Ext simple_molecule
gadEF-mdtEF_mRNA MdtF
Name: gadEF-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtF
Components:
Function Name Type
product MdtF protein
reactant gadEF-mdtEF_mRNA RNA



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