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GadE Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
(3R)-3-hydroxy cis delta7-tetradecenoyl-[acp] MdtE FlgI GABA beta-hydroxymyristoyl-[acp] FlgK beta-hydroxyhexanoyl-[acp] guanosine-diphosphate UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine FlgI gadBC FlgG CH3(CH2)xCH=CHCO-S-ACP FlgH FliQ FliD MotB gltBDF_mRNA (3R)-3-hydroxy-cis-vaccenoyl-[acp] FliH MdtF HdeD UDP-2,3-diacyl-glucosamine L-glutamate Trans-D2-cis-D7-tetradecenoyl-ACPs 3-hydroxypimeloyl-[acp] methyl ester FliN beta-hydroxydodecanoyl-[acp] (2E)-dodec-2-enoyl-[acp] FliP This Gensor Unit is not yet available ubiquinol_Ext FliM beta-OH-acyl-ACP crotonyl-[acp] phosphate FlgL FlgC FlhB rcsA_mRNA FliG CyoE (2E)-dec-2-enoyl-[acp] farnesyl-PP skp-lpxD-fabZ-lpxA_mRNA fliC FliJ FliC FliO FliP FlgK UDP-3-O-(3-hydroxytetradecanoyl)glucosamine LpxD gadEF_mRNA CyoC lrp UDP-GlcNAc GadC trans tetradec-2-enoyl-[acp] GltF FliF TolC FliM gnd_mRNA FliN FliQ CyoB FliR YhiD FliG GltB GadW rcsA hdeAB-yhiD MdtF PurA Lrp FlhA FlgG MdtE GltD FliJ lrp_mRNA MotA L-glutamate_Ext gadEF FliC GltB diphosphate oxygen_Ext RcsA FliE drug_Ext guanosine-triphosphate CyoA CyoA FliL FlgF FlgB FlgC This Gensor Unit is not yet available gadBC_mRNA FliI gadEF-mdtEF (2E,11Z)-octadeca-2,11-dienoyl-[acp] HdeB cyoABCDE hdeD GABA_Ext 5'-IMP adenylo-succinate protoheme IX RNA:GadF CyoD CyoD FliL LpxA RcsB cyoABCDE_mRNA FlhA FliO FabZ Skp ribulose-5P skp-lpxD-fabZ-lpxA trans-delta3-cis-delta9-hexadecenoyl-[acp] CyoB FliH FliI RcsB AcpP RcsA CyoC ubiquinone FliR gnd GltD MotB trans hexadecenoyl-[acp] 6-p gluconate RcsB FlgF GadE drug hdeAB-yhiD_mRNA FlgB beta-hydroxydecanoyl-[acp] FlhB trans hex-2-enoyl-[acp] FliF aspartate Gnd gadEF-mdtEF_mRNA enoylglutaryl-[acp] methyl ester (3R)-3-hydroxyglutaryl-[acp] methyl ester HdeA FlgH FliE purA_mRNA enoylpimelyl-[acp] methyl ester FlgE ferroheme o fliC_mRNA GadB GadE FlgL gltBDF This Gensor Unit is not yet available purA FlgE (3R)-3-hydroxy cis delta9-hexadecenoyl-[acp] hdeD_mRNA FliD MotA This Gensor Unit is not yet available TolC GadX CO2 AcpP beta-hydroxymyristoyl-[acp] FabZ AcpP


Gensor Unit       
Name: GadE
Classification:
Groups: Cell motility
Lipid transport and metabolism
Transcription
Carbohydrate transport and metabolism
Energy production and conversion
Signal transduction mechanisms
Amino acid transport and metabolism
Coenzyme transport and metabolism
Defense mechanisms
Cell wall/membrane/envelope biogenesis
Nucleotide transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0044208 - 'de novo' AMP biosynthetic process
GO:0042773 - ATP synthesis coupled electron transport
GO:0046177 - D-gluconate catabolic process
GO:0019521 - D-gluconate metabolic process
GO:0043165 - Gram-negative-bacterium-type cell outer membrane assembly
GO:0046040 - IMP metabolic process
Read more >
cellular_component GO:0009288 - bacterial-type flagellum
GO:0009420 - bacterial-type flagellum filament
GO:0009279 - cell outer membrane
GO:0009319 - cytochrome o ubiquinol oxidase complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005576 - extracellular region
Read more >
molecular_function GO:0051538 - 3 iron, 4 sulfur cluster binding
GO:0019171 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
GO:0008693 - 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
GO:0047451 - 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0003677 - DNA binding
GO:0001216 - DNA-binding transcription activator activity
Read more >
Components:
  Function Name Type
  simple_molecule (2E)-dec-2-enoyl-[acp] simple_molecule
  simple_molecule (2E)-dodec-2-enoyl-[acp] simple_molecule
  simple_molecule (2E,11Z)-octadeca-2,11-dienoyl-[acp] simple_molecule
  simple_molecule (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] simple_molecule
  simple_molecule (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] simple_molecule
  simple_molecule (3R)-3-hydroxy-cis-vaccenoyl-[acp] simple_molecule
  simple_molecule (3R)-3-hydroxyglutaryl-[acp] methyl ester simple_molecule
  simple_molecule 3-hydroxypimeloyl-[acp] methyl ester simple_molecule
  simple_molecule 5'-IMP simple_molecule
  simple_molecule 6-p gluconate simple_molecule
  simple_molecule AcpP simple_molecule
  simple_molecule CH3(CH2)xCH=CHCO-S-ACP simple_molecule
  simple_molecule CO2 simple_molecule
  protein CyoA protein
  protein CyoB protein
  protein CyoC protein
  protein CyoD protein
  complex CyoD-CyoA-CyoB-CyoC complex
  protein CyoE protein
  protein FabZ protein
  protein FlgB protein
  protein FlgC protein
  protein FlgE protein
  protein FlgF protein
  protein FlgG protein
  protein FlgH protein
  protein FlgI protein
  protein FlgK protein
  protein FlgL protein
  protein FlhA protein
  protein FlhB protein
  protein FliC protein
  protein FliD protein
  protein FliE protein
  protein FliF protein
  protein FliG protein
  protein FliH protein
  protein FliI protein
  protein FliJ protein
  protein FliL protein
  complex FliL-FliE-FliF-FlgI-FlgG-FlgF-FlgC-FlgB-MotB-MotA-FlgH-FliG-FliM-FliN-FliJ-FliI-FliH-FliR-FliQ-FliP-FliO-FlhB-FlhA-FlgE-FlgK-FlgL-FliC-FliD complex
  protein FliM protein
  protein FliN protein
  protein FliO protein
  protein FliP protein
  protein FliQ protein
  protein FliR protein
  simple_molecule GABA simple_molecule
  simple_molecule GABA_Ext simple_molecule
  protein GadB protein
  protein GadC protein
  protein GadE protein
  protein GadW protein
  protein GadX protein
  protein GltB protein
  protein GltD protein
  complex GltD-GltB complex
  protein GltF protein
  protein Gnd protein
  protein HdeA protein
  protein HdeB protein
  protein HdeD protein
  simple_molecule L-glutamate simple_molecule
  simple_molecule L-glutamate_Ext simple_molecule
  protein LpxA protein
  protein LpxD protein
  protein Lrp protein
  protein MdtE protein
  protein MdtF protein
  protein MotA protein
  protein MotB protein
  protein PurA protein
  protein RNA:GadF protein
  protein RcsA protein
  protein RcsB protein
  complex RcsB-GadE complex
  complex RcsB-RcsA complex
  protein Skp protein
  protein TolC protein
  complex TolC-MdtE-MdtF complex
  simple_molecule Trans-D2-cis-D7-tetradecenoyl-ACPs simple_molecule
  simple_molecule UDP-2,3-diacyl-glucosamine simple_molecule
  simple_molecule UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine simple_molecule
  simple_molecule UDP-3-O-(3-hydroxytetradecanoyl)glucosamine simple_molecule
  simple_molecule UDP-GlcNAc simple_molecule
  protein YhiD protein
  simple_molecule adenylo-succinate simple_molecule
  simple_molecule aspartate simple_molecule
  simple_molecule beta-OH-acyl-ACP simple_molecule
  simple_molecule beta-hydroxydecanoyl-[acp] simple_molecule
  simple_molecule beta-hydroxydodecanoyl-[acp] simple_molecule
  simple_molecule beta-hydroxyhexanoyl-[acp] simple_molecule
  simple_molecule beta-hydroxymyristoyl-[acp] simple_molecule
  simple_molecule crotonyl-[acp] simple_molecule
  gene cyoABCDE gene
  RNA cyoABCDE_mRNA RNA
  simple_molecule diphosphate simple_molecule
  simple_molecule drug simple_molecule
  simple_molecule drug_Ext simple_molecule
  simple_molecule enoylglutaryl-[acp] methyl ester simple_molecule
  simple_molecule enoylpimelyl-[acp] methyl ester simple_molecule
  simple_molecule farnesyl-PP simple_molecule
  simple_molecule ferroheme o simple_molecule
  gene fliC gene
  RNA fliC_mRNA RNA
  gene gadBC gene
  RNA gadBC_mRNA RNA
  gene gadEF gene
  gene gadEF-mdtEF gene
  RNA gadEF-mdtEF_mRNA RNA
  RNA gadEF_mRNA RNA
  gene gadX gene
  gene gadXW gene
  RNA gadXW_mRNA RNA
  RNA gadX_mRNA RNA
  gene gltBDF gene
  RNA gltBDF_mRNA RNA
  gene gnd gene
  RNA gnd_mRNA RNA
  simple_molecule guanosine-diphosphate simple_molecule
  simple_molecule guanosine-triphosphate simple_molecule
  gene hdeAB-yhiD gene
  RNA hdeAB-yhiD_mRNA RNA
  gene hdeD gene
  RNA hdeD_mRNA RNA
  gene lrp gene
  RNA lrp_mRNA RNA
  simple_molecule oxygen_Ext simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule protoheme IX simple_molecule
  gene purA gene
  RNA purA_mRNA RNA
  gene rcsA gene
  RNA rcsA_mRNA RNA
  simple_molecule ribulose-5P simple_molecule
  gene skp-lpxD-fabZ-lpxA gene
  RNA skp-lpxD-fabZ-lpxA_mRNA RNA
  simple_molecule trans hex-2-enoyl-[acp] simple_molecule
  simple_molecule trans hexadecenoyl-[acp] simple_molecule
  simple_molecule trans tetradec-2-enoyl-[acp] simple_molecule
  simple_molecule trans-Δ3-cis-Δ9-hexadecenoyl-[acp] simple_molecule
  simple_molecule ubiquinol_Ext simple_molecule
  simple_molecule ubiquinone simple_molecule


Reactions       
Showing 86 reactions
GadE cyoABCDE cyoABCDE_mRNA
Name: cyoABCDE -> cyoABCDE_mRNA
Description: Transcription of transcription unit cyoABCDE. Reaction activation by GadE.
Type: transcription
Pathway Components: cyoABCDE - GadE -> cyoABCDE_mRNA
Components:
Function Name Type
activator GadE protein
reactant cyoABCDE gene
product cyoABCDE_mRNA RNA
GadE fliC fliC_mRNA
Name: fliC -> fliC_mRNA
Description: Transcription of transcription unit fliC. Reaction activation by GadE.
Type: transcription
Pathway Components: fliC - GadE -> fliC_mRNA
Components:
Function Name Type
activator GadE protein
reactant fliC gene
product fliC_mRNA RNA
GadE gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC. Reaction activation by GadE.
Type: transcription
Pathway Components: gadBC - GadE -> gadBC_mRNA
Components:
Function Name Type
activator GadE protein
reactant gadBC gene
product gadBC_mRNA RNA
GadE gadEF gadEF_mRNA
Name: gadEF -> gadEF_mRNA
Description: Transcription of transcription unit gadEF. Reaction activation by GadE.
Type: transcription
Pathway Components: gadEF - GadE -> gadEF_mRNA
Components:
Function Name Type
activator GadE protein
reactant gadEF gene
product gadEF_mRNA RNA
GadE gadEF-mdtEF gadEF-mdtEF_mRNA
Name: gadEF-mdtEF -> gadEF-mdtEF_mRNA
Description: Transcription of transcription unit gadEF-mdtEF. Reaction activation by GadE.
Type: transcription
Pathway Components: gadEF-mdtEF - GadE -> gadEF-mdtEF_mRNA
Components:
Function Name Type
activator GadE protein
reactant gadEF-mdtEF gene
product gadEF-mdtEF_mRNA RNA
GadE gadX gadX_mRNA
Name: gadX -> gadX_mRNA
Description: Transcription of transcription unit gadX. Reaction activation by GadE.
Type: transcription
Pathway Components: gadX - GadE -> gadX_mRNA
Components:
Function Name Type
activator GadE protein
reactant gadX gene
product gadX_mRNA RNA
GadE gadXW gadXW_mRNA
Name: gadXW -> gadXW_mRNA
Description: Transcription of transcription unit gadXW. Reaction activation by GadE.
Type: transcription
Pathway Components: gadXW - GadE -> gadXW_mRNA
Components:
Function Name Type
activator GadE protein
reactant gadXW gene
product gadXW_mRNA RNA
GadE gltBDF gltBDF_mRNA
Name: gltBDF -> gltBDF_mRNA
Description: Transcription of transcription unit gltBDF. Reaction activation by GadE.
Type: transcription
Pathway Components: gltBDF - GadE -> gltBDF_mRNA
Components:
Function Name Type
activator GadE protein
reactant gltBDF gene
product gltBDF_mRNA RNA
GadE gnd gnd_mRNA
Name: gnd -> gnd_mRNA
Description: Transcription of transcription unit gnd. Reaction activation by GadE.
Type: transcription
Pathway Components: gnd - GadE -> gnd_mRNA
Components:
Function Name Type
activator GadE protein
reactant gnd gene
product gnd_mRNA RNA
GadE hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction activation by GadE.
Type: transcription
Pathway Components: hdeAB-yhiD - GadE -> hdeAB-yhiD_mRNA
Components:
Function Name Type
activator GadE protein
reactant hdeAB-yhiD gene
product hdeAB-yhiD_mRNA RNA
GadE hdeD hdeD_mRNA
Name: hdeD -> hdeD_mRNA
Description: Transcription of transcription unit hdeD. Reaction activation by GadE.
Type: transcription
Pathway Components: hdeD - GadE -> hdeD_mRNA
Components:
Function Name Type
activator GadE protein
reactant hdeD gene
product hdeD_mRNA RNA
GadE lrp lrp_mRNA
Name: lrp -> lrp_mRNA
Description: Transcription of transcription unit lrp. Reaction activation by GadE.
Type: transcription
Pathway Components: lrp - GadE -> lrp_mRNA
Components:
Function Name Type
activator GadE protein
reactant lrp gene
product lrp_mRNA RNA
GadE purA purA_mRNA
Name: purA -> purA_mRNA
Description: Transcription of transcription unit purA. Reaction activation by GadE.
Type: transcription
Pathway Components: purA - GadE -> purA_mRNA
Components:
Function Name Type
activator GadE protein
reactant purA gene
product purA_mRNA RNA
GadE rcsA rcsA_mRNA
Name: rcsA -> rcsA_mRNA
Description: Transcription of transcription unit rcsA. Reaction activation by GadE.
Type: transcription
Pathway Components: rcsA - GadE -> rcsA_mRNA
Components:
Function Name Type
activator GadE protein
reactant rcsA gene
product rcsA_mRNA RNA
GadE skp-lpxD-fabZ-lpxA skp-lpxD-fabZ-lpxA_mRNA
Name: skp-lpxD-fabZ-lpxA -> skp-lpxD-fabZ-lpxA_mRNA
Description: Transcription of transcription unit skp-lpxD-fabZ-lpxA. Reaction activation by GadE.
Type: transcription
Pathway Components: skp-lpxD-fabZ-lpxA - GadE -> skp-lpxD-fabZ-lpxA_mRNA
Components:
Function Name Type
activator GadE protein
reactant skp-lpxD-fabZ-lpxA gene
product skp-lpxD-fabZ-lpxA_mRNA RNA
gadXW_mRNA GadX
Name: gadXW_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadXW_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadXW_mRNA RNA
gadXW_mRNA GadW
Name: gadXW_mRNA -> GadW
Description: Translation of GadW
Type: translation
Pathway Components: gadXW_mRNA -> GadW
Components:
Function Name Type
product GadW protein
reactant gadXW_mRNA RNA
gltBDF_mRNA GltB
Name: gltBDF_mRNA -> GltB
Description: Translation of GltB
Type: translation
Pathway Components: gltBDF_mRNA -> GltB
Components:
Function Name Type
product GltB protein
reactant gltBDF_mRNA RNA
GltD + GltB GltD-GltB
Name: GltD + GltB -> GltD-GltB
Description: Reaction transforming GltD, GltB into GltD-GltB
Type: state transition
Pathway Components: GltD + GltB -> GltD-GltB
Components:
Function Name Type
reactant GltB protein
reactant GltD protein
product GltD-GltB complex
gltBDF_mRNA GltD
Name: gltBDF_mRNA -> GltD
Description: Translation of GltD
Type: translation
Pathway Components: gltBDF_mRNA -> GltD
Components:
Function Name Type
product GltD protein
reactant gltBDF_mRNA RNA
gltBDF_mRNA GltF
Name: gltBDF_mRNA -> GltF
Description: Translation of GltF
Type: translation
Pathway Components: gltBDF_mRNA -> GltF
Components:
Function Name Type
product GltF protein
reactant gltBDF_mRNA RNA
fliC_mRNA FliC
Name: fliC_mRNA -> FliC
Description: Translation of FliC
Type: translation
Pathway Components: fliC_mRNA -> FliC
Components:
Function Name Type
product FliC protein
reactant fliC_mRNA RNA
Protein Monomers Protein complex
Name: FliD + FlgH + FlgF + MotA + FlgC + FlgL + MotB + FlgB + FliF + FlgE + FliQ + FlhA + FliR + FlgK + FliO + FliL + FliE + FliI + FliH + FliM + FliN + FlgG + FliP + FliC + FlhB + FliG + FliJ + FlgI -> FliL-FliE-FliF-FlgI-FlgG-FlgF-FlgC-FlgB-MotB-MotA-FlgH-FliG-FliM-FliN-FliJ-FliI-FliH-FliR-FliQ-FliP-FliO-FlhB-FlhA-FlgE-FlgK-FlgL-FliC-FliD
Description: Reaction transforming FliD, FlgH, FlgF, MotA, FlgC, FlgL, MotB, FlgB, FliF, FlgE, FliQ, FlhA, FliR, FlgK, FliO, FliL, FliE, FliI, FliH, FliM, FliN, FlgG, FliP, FliC, FlhB, FliG, FliJ, FlgI into FliL-FliE-FliF-FlgI-FlgG-FlgF-FlgC-FlgB-MotB-MotA-FlgH-FliG-FliM-FliN-FliJ-FliI-FliH-FliR-FliQ-FliP-FliO-FlhB-FlhA-FlgE-FlgK-FlgL-FliC-FliD
Type: state transition
Pathway Components: FliD + FlgH + FlgF + MotA + FlgC + FlgL + MotB + FlgB + FliF + FlgE + FliQ + FlhA + FliR + FlgK + FliO + FliL + FliE + FliI + FliH + FliM + FliN + FlgG + FliP + FliC + FlhB + FliG + FliJ + FlgI -> FliL-FliE-FliF-FlgI-FlgG-FlgF-FlgC-FlgB-MotB-MotA-FlgH-FliG-FliM-FliN-FliJ-FliI-FliH-FliR-FliQ-FliP-FliO-FlhB-FlhA-FlgE-FlgK-FlgL-FliC-FliD
Components: Show/Hide Components Table
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type
product HdeA protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type
product HdeB protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type
product YhiD protein
reactant hdeAB-yhiD_mRNA RNA
rcsA_mRNA RcsA
Name: rcsA_mRNA -> RcsA
Description: Translation of RcsA
Type: translation
Pathway Components: rcsA_mRNA -> RcsA
Components:
Function Name Type
product RcsA protein
reactant rcsA_mRNA RNA
RcsB + RcsA RcsB-RcsA
Name: RcsB + RcsA -> RcsB-RcsA
Description: Reaction transforming RcsB, RcsA into RcsB-RcsA
Type: state transition
Pathway Components: RcsB + RcsA -> RcsB-RcsA
Components:
Function Name Type
reactant RcsA protein
reactant RcsB protein
product RcsB-RcsA complex
lrp_mRNA Lrp
Name: lrp_mRNA -> Lrp
Description: Translation of Lrp
Type: translation
Pathway Components: lrp_mRNA -> Lrp
Components:
Function Name Type
product Lrp protein
reactant lrp_mRNA RNA
cyoABCDE_mRNA CyoA
Name: cyoABCDE_mRNA -> CyoA
Description: Translation of CyoA
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoA
Components:
Function Name Type
product CyoA protein
reactant cyoABCDE_mRNA RNA
CyoD + CyoC + CyoB + CyoA CyoD-CyoA-CyoB-CyoC
Name: CyoD + CyoC + CyoB + CyoA -> CyoD-CyoA-CyoB-CyoC
Description: Reaction transforming CyoD, CyoC, CyoB, CyoA into CyoD-CyoA-CyoB-CyoC
Type: state transition
Pathway Components: CyoD + CyoC + CyoB + CyoA -> CyoD-CyoA-CyoB-CyoC
Components:
Function Name Type
reactant CyoA protein
reactant CyoB protein
reactant CyoC protein
reactant CyoD protein
product CyoD-CyoA-CyoB-CyoC complex
CyoD-CyoA-CyoB-CyoC ubiquinol_Ext + oxygen_Ext ubiquinone
Name: ubiquinol_Ext + oxygen_Ext -> ubiquinone
Description: Transport of ubiquinol_Ext, oxygen_Ext through a bacterial membrane, leading to the presence of ubiquinone inside the cell.
Type: transport
Pathway Components: ubiquinol_Ext + oxygen_Ext - CyoD-CyoA-CyoB-CyoC -> ubiquinone
Components:
Function Name Type
catalyzer CyoD-CyoA-CyoB-CyoC complex
reactant oxygen_Ext simple_molecule
reactant ubiquinol_Ext simple_molecule
product ubiquinone simple_molecule
cyoABCDE_mRNA CyoB
Name: cyoABCDE_mRNA -> CyoB
Description: Translation of CyoB
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoB
Components:
Function Name Type
product CyoB protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoC
Name: cyoABCDE_mRNA -> CyoC
Description: Translation of CyoC
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoC
Components:
Function Name Type
product CyoC protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoD
Name: cyoABCDE_mRNA -> CyoD
Description: Translation of CyoD
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoD
Components:
Function Name Type
product CyoD protein
reactant cyoABCDE_mRNA RNA
cyoABCDE_mRNA CyoE
Name: cyoABCDE_mRNA -> CyoE
Description: Translation of CyoE
Type: translation
Pathway Components: cyoABCDE_mRNA -> CyoE
Components:
Function Name Type
product CyoE protein
reactant cyoABCDE_mRNA RNA
CyoE protoheme IX + farnesyl-PP diphosphate + ferroheme o
Name: protoheme IX + farnesyl-PP -> diphosphate + ferroheme o
Description: Reaction transforming protoheme IX, farnesyl-PP into diphosphate, ferroheme o
Type: state transition
Pathway Components: protoheme IX + farnesyl-PP - CyoE -> diphosphate + ferroheme o
Components:
Function Name Type
catalyzer CyoE protein
product diphosphate simple_molecule
reactant farnesyl-PP simple_molecule
product ferroheme o simple_molecule
reactant protoheme IX simple_molecule
gadEF-mdtEF_mRNA GadE
Name: gadEF-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> GadE
Components:
Function Name Type
product GadE protein
reactant gadEF-mdtEF_mRNA RNA
GadE + RcsB RcsB-GadE
Name: GadE + RcsB -> RcsB-GadE
Description: Reaction transforming GadE, RcsB into RcsB-GadE
Type: state transition
Pathway Components: GadE + RcsB -> RcsB-GadE
Components:
Function Name Type
reactant GadE protein
reactant RcsB protein
product RcsB-GadE complex
gadEF-mdtEF_mRNA RNA:GadF
Name: gadEF-mdtEF_mRNA -> RNA:GadF
Description: Translation of RNA:GadF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> RNA:GadF
Components:
Function Name Type
product RNA:GadF protein
reactant gadEF-mdtEF_mRNA RNA
gadEF-mdtEF_mRNA MdtE
Name: gadEF-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtE
Components:
Function Name Type
product MdtE protein
reactant gadEF-mdtEF_mRNA RNA
TolC + MdtF + MdtE TolC-MdtE-MdtF
Name: TolC + MdtF + MdtE -> TolC-MdtE-MdtF
Description: Reaction transforming TolC, MdtF, MdtE into TolC-MdtE-MdtF
Type: state transition
Pathway Components: TolC + MdtF + MdtE -> TolC-MdtE-MdtF
Components:
Function Name Type
reactant MdtE protein
reactant MdtF protein
reactant TolC protein
product TolC-MdtE-MdtF complex
TolC-MdtE-MdtF drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - TolC-MdtE-MdtF -> drug
Components:
Function Name Type
catalyzer TolC-MdtE-MdtF complex
product drug simple_molecule
reactant drug_Ext simple_molecule
gadEF-mdtEF_mRNA MdtF
Name: gadEF-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtF
Components:
Function Name Type
product MdtF protein
reactant gadEF-mdtEF_mRNA RNA
skp-lpxD-fabZ-lpxA_mRNA Skp
Name: skp-lpxD-fabZ-lpxA_mRNA -> Skp
Description: Translation of Skp
Type: translation
Pathway Components: skp-lpxD-fabZ-lpxA_mRNA -> Skp
Components:
Function Name Type
product Skp protein
reactant skp-lpxD-fabZ-lpxA_mRNA RNA
skp-lpxD-fabZ-lpxA_mRNA LpxD
Name: skp-lpxD-fabZ-lpxA_mRNA -> LpxD
Description: Translation of LpxD
Type: translation
Pathway Components: skp-lpxD-fabZ-lpxA_mRNA -> LpxD
Components:
Function Name Type
product LpxD protein
reactant skp-lpxD-fabZ-lpxA_mRNA RNA
AcpP LpxD Reactants UDP-2,3-diacyl-glucosamine + AcpP
Name: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + beta-hydroxymyristoyl-[acp] -> UDP-2,3-diacyl-glucosamine + AcpP
Description: Reaction transforming UDP-3-O-(3-hydroxytetradecanoyl)glucosamine, beta-hydroxymyristoyl-[acp] into UDP-2,3-diacyl-glucosamine, AcpP
Type: state transition
Pathway Components: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + beta-hydroxymyristoyl-[acp] - LpxD - AcpP -> UDP-2,3-diacyl-glucosamine + AcpP
Components:
Function Name Type
inhibitor AcpP simple_molecule
product AcpP simple_molecule
catalyzer LpxD protein
product UDP-2,3-diacyl-glucosamine simple_molecule
reactant UDP-3-O-(3-hydroxytetradecanoyl)glucosamine simple_molecule
reactant beta-hydroxymyristoyl-[acp] simple_molecule
skp-lpxD-fabZ-lpxA_mRNA FabZ
Name: skp-lpxD-fabZ-lpxA_mRNA -> FabZ
Description: Translation of FabZ
Type: translation
Pathway Components: skp-lpxD-fabZ-lpxA_mRNA -> FabZ
Components:
Function Name Type
product FabZ protein
reactant skp-lpxD-fabZ-lpxA_mRNA RNA
FabZ (3R)-3-hydroxyglutaryl-[acp] methyl ester enoylglutaryl-[acp] methyl ester
Name: (3R)-3-hydroxyglutaryl-[acp] methyl ester -> enoylglutaryl-[acp] methyl ester
Description: Reaction transforming (3R)-3-hydroxyglutaryl-[acp] methyl ester into enoylglutaryl-[acp] methyl ester
Type: state transition
Pathway Components: (3R)-3-hydroxyglutaryl-[acp] methyl ester - FabZ -> enoylglutaryl-[acp] methyl ester
Components:
Function Name Type
reactant (3R)-3-hydroxyglutaryl-[acp] methyl ester simple_molecule
catalyzer FabZ protein
product enoylglutaryl-[acp] methyl ester simple_molecule
FabZ 3-hydroxypimeloyl-[acp] methyl ester enoylpimelyl-[acp] methyl ester
Name: 3-hydroxypimeloyl-[acp] methyl ester -> enoylpimelyl-[acp] methyl ester
Description: Reaction transforming 3-hydroxypimeloyl-[acp] methyl ester into enoylpimelyl-[acp] methyl ester
Type: state transition
Pathway Components: 3-hydroxypimeloyl-[acp] methyl ester - FabZ -> enoylpimelyl-[acp] methyl ester
Components:
Function Name Type
reactant 3-hydroxypimeloyl-[acp] methyl ester simple_molecule
catalyzer FabZ protein
product enoylpimelyl-[acp] methyl ester simple_molecule
FabZ (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] Trans-D2-cis-D7-tetradecenoyl-ACPs
Name: (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] -> Trans-D2-cis-D7-tetradecenoyl-ACPs
Description: Reaction transforming (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] into Trans-D2-cis-D7-tetradecenoyl-ACPs
Type: state transition
Pathway Components: (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] - FabZ -> Trans-D2-cis-D7-tetradecenoyl-ACPs
Components:
Function Name Type
reactant (3R)-3-hydroxy cis Δ7-tetradecenoyl-[acp] simple_molecule
catalyzer FabZ protein
product Trans-D2-cis-D7-tetradecenoyl-ACPs simple_molecule
FabZ (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] trans-Δ3-cis-Δ9-hexadecenoyl-[acp]
Name: (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] -> trans-Δ3-cis-Δ9-hexadecenoyl-[acp]
Description: Reaction transforming (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] into trans-Δ3-cis-Δ9-hexadecenoyl-[acp]
Type: state transition
Pathway Components: (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] - FabZ -> trans-Δ3-cis-Δ9-hexadecenoyl-[acp]
Components:
Function Name Type
reactant (3R)-3-hydroxy cis Δ9-hexadecenoyl-[acp] simple_molecule
catalyzer FabZ protein
product trans-Δ3-cis-Δ9-hexadecenoyl-[acp] simple_molecule
FabZ beta-OH-acyl-ACP CH3(CH2)xCH=CHCO-S-ACP
Name: beta-OH-acyl-ACP -> CH3(CH2)xCH=CHCO-S-ACP
Description: Reaction transforming beta-OH-acyl-ACP into CH3(CH2)xCH=CHCO-S-ACP
Type: state transition
Pathway Components: beta-OH-acyl-ACP - FabZ -> CH3(CH2)xCH=CHCO-S-ACP
Components:
Function Name Type
product CH3(CH2)xCH=CHCO-S-ACP simple_molecule
catalyzer FabZ protein
reactant beta-OH-acyl-ACP simple_molecule
FabZ (3R)-3-hydroxy-cis-vaccenoyl-[acp] (2E,11Z)-octadeca-2,11-dienoyl-[acp]
Name: (3R)-3-hydroxy-cis-vaccenoyl-[acp] -> (2E,11Z)-octadeca-2,11-dienoyl-[acp]
Description: Reaction transforming (3R)-3-hydroxy-cis-vaccenoyl-[acp] into (2E,11Z)-octadeca-2,11-dienoyl-[acp]
Type: state transition
Pathway Components: (3R)-3-hydroxy-cis-vaccenoyl-[acp] - FabZ -> (2E,11Z)-octadeca-2,11-dienoyl-[acp]
Components:
Function Name Type
product (2E,11Z)-octadeca-2,11-dienoyl-[acp] simple_molecule
reactant (3R)-3-hydroxy-cis-vaccenoyl-[acp] simple_molecule
catalyzer FabZ protein
FabZ AcpP crotonyl-[acp]
Name: AcpP -> crotonyl-[acp]
Description: Reaction transforming AcpP into crotonyl-[acp]
Type: state transition
Pathway Components: AcpP - FabZ -> crotonyl-[acp]
Components:
Function Name Type
reactant AcpP simple_molecule
catalyzer FabZ protein
product crotonyl-[acp] simple_molecule
FabZ beta-hydroxymyristoyl-[acp] trans tetradec-2-enoyl-[acp]
Name: beta-hydroxymyristoyl-[acp] -> trans tetradec-2-enoyl-[acp]
Description: Reaction transforming beta-hydroxymyristoyl-[acp] into trans tetradec-2-enoyl-[acp]
Type: state transition
Pathway Components: beta-hydroxymyristoyl-[acp] - FabZ -> trans tetradec-2-enoyl-[acp]
Components:
Function Name Type
catalyzer FabZ protein
reactant beta-hydroxymyristoyl-[acp] simple_molecule
product trans tetradec-2-enoyl-[acp] simple_molecule
FabZ beta-hydroxydodecanoyl-[acp]