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GadE-RcsB Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
yhiM_mRNA aslB cadBA_mRNA GABA adiC GadA agmatine_Ext YhiM GadX CadB gadAX adiC_mRNA CO2 agmatine BioDex 1-_Ext BioDex 1- LdcI lysine_Ext gadAX_mRNA cadBA lysine GadE-RcsB L-glutamate slp-dctR Slp slp-dctR_mRNA AdiC yhiM AslB aslB_mRNA DctR CadA arginine_Ext


Gensor Unit       
Name: GadE-RcsB
Classification:
Groups: Posttranslational modification, protein turnover, chaperones
Transcription
Signal transduction mechanisms
Amino acid transport and metabolism
Cell wall/membrane/envelope biogenesis
Gene Ontology Terms (GO): biological_process GO:1903401 - L-lysine transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:1903826 - arginine transmembrane transport
GO:0001121 - bacterial transcription
GO:0015839 - cadaverine transport
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cellular_component GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0019867 - outer membrane
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molecular_function GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0015171 - amino acid transmembrane transporter activity
GO:0015297 - antiporter activity
GO:0015181 - arginine transmembrane transporter activity
GO:0000986 - bacterial-type cis-regulatory region sequence-specific DNA binding
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Components:
  Function Name Type
  protein AdiC protein
  protein AslB protein
  simple_molecule BioDex 1- simple_molecule
  simple_molecule BioDex 1-_Ext simple_molecule
  simple_molecule CO2 simple_molecule
  protein CadA protein
  protein CadB protein
  protein DctR protein
  simple_molecule GABA simple_molecule
  protein GadA protein
  protein GadE-RcsB protein
  protein GadX protein
  simple_molecule L-glutamate simple_molecule
  protein LdcI protein
  protein Slp protein
  protein YhiM protein
  gene adiC gene
  RNA adiC_mRNA RNA
  simple_molecule agmatine simple_molecule
  simple_molecule agmatine_Ext simple_molecule
  simple_molecule arginine simple_molecule
  simple_molecule arginine_Ext simple_molecule
  gene aslB gene
  RNA aslB_mRNA RNA
  gene cadBA gene
  RNA cadBA_mRNA RNA
  gene gadAX gene
  RNA gadAX_mRNA RNA
  simple_molecule lysine simple_molecule
  simple_molecule lysine_Ext simple_molecule
  gene slp-dctR gene
  RNA slp-dctR_mRNA RNA
  gene yhiM gene
  RNA yhiM_mRNA RNA


Reactions       
Showing 21 reactions
GadE-RcsB adiC adiC_mRNA
Name: adiC -> adiC_mRNA
Description: Transcription of transcription unit adiC. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: adiC - GadE-RcsB -> adiC_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant adiC gene
product adiC_mRNA RNA
GadE-RcsB aslB aslB_mRNA
Name: aslB -> aslB_mRNA
Description: Transcription of transcription unit aslB. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: aslB - GadE-RcsB -> aslB_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant aslB gene
product aslB_mRNA RNA
GadE-RcsB cadBA cadBA_mRNA
Name: cadBA -> cadBA_mRNA
Description: Transcription of transcription unit cadBA. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: cadBA - GadE-RcsB -> cadBA_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant cadBA gene
product cadBA_mRNA RNA
GadE-RcsB gadAX gadAX_mRNA
Name: gadAX -> gadAX_mRNA
Description: Transcription of transcription unit gadAX. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: gadAX - GadE-RcsB -> gadAX_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant gadAX gene
product gadAX_mRNA RNA
GadE-RcsB slp-dctR slp-dctR_mRNA
Name: slp-dctR -> slp-dctR_mRNA
Description: Transcription of transcription unit slp-dctR. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: slp-dctR - GadE-RcsB -> slp-dctR_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant slp-dctR gene
product slp-dctR_mRNA RNA
GadE-RcsB yhiM yhiM_mRNA
Name: yhiM -> yhiM_mRNA
Description: Transcription of transcription unit yhiM. Reaction activation by GadE-RcsB.
Type: transcription
Pathway Components: yhiM - GadE-RcsB -> yhiM_mRNA
Components:
Function Name Type
activator GadE-RcsB protein
reactant yhiM gene
product yhiM_mRNA RNA
adiC_mRNA AdiC
Name: adiC_mRNA -> AdiC
Description: Translation of AdiC
Type: translation
Pathway Components: adiC_mRNA -> AdiC
Components:
Function Name Type
product AdiC protein
reactant adiC_mRNA RNA
AdiC agmatine_Ext + arginine_Ext agmatine + arginine
Name: agmatine_Ext + arginine_Ext -> agmatine + arginine
Description: Transport of agmatine_Ext, arginine_Ext through a bacterial membrane, leading to the presence of agmatine, arginine inside the cell.
Type: transport
Pathway Components: agmatine_Ext + arginine_Ext - AdiC -> agmatine + arginine
Components:
Function Name Type
catalyzer AdiC protein
product agmatine simple_molecule
reactant agmatine_Ext simple_molecule
product arginine simple_molecule
reactant arginine_Ext simple_molecule
yhiM_mRNA YhiM
Name: yhiM_mRNA -> YhiM
Description: Translation of YhiM
Type: translation
Pathway Components: yhiM_mRNA -> YhiM
Components:
Function Name Type
product YhiM protein
reactant yhiM_mRNA RNA
cadBA_mRNA CadB
Name: cadBA_mRNA -> CadB
Description: Translation of CadB
Type: translation
Pathway Components: cadBA_mRNA -> CadB
Components:
Function Name Type
product CadB protein
reactant cadBA_mRNA RNA
CadB BioDex 1-_Ext + lysine_Ext BioDex 1- + lysine
Name: BioDex 1-_Ext + lysine_Ext -> BioDex 1- + lysine
Description: Transport of BioDex 1-_Ext, lysine_Ext through a bacterial membrane, leading to the presence of BioDex 1-, lysine inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext + lysine_Ext - CadB -> BioDex 1- + lysine
Components:
Function Name Type
product BioDex 1- simple_molecule
reactant BioDex 1-_Ext simple_molecule
catalyzer CadB protein
product lysine simple_molecule
reactant lysine_Ext simple_molecule
CadB BioDex 1-_Ext BioDex 1-
Name: BioDex 1-_Ext -> BioDex 1-
Description: Transport of BioDex 1-_Ext through a bacterial membrane, leading to the presence of BioDex 1- inside the cell.
Type: transport
Pathway Components: BioDex 1-_Ext - CadB -> BioDex 1-
Components:
Function Name Type
product BioDex 1- simple_molecule
reactant BioDex 1-_Ext simple_molecule
catalyzer CadB protein
cadBA_mRNA CadA
Name: cadBA_mRNA -> CadA
Description: Translation of CadA
Type: translation
Pathway Components: cadBA_mRNA -> CadA
Components:
Function Name Type
product CadA protein
reactant cadBA_mRNA RNA
CadA LdcI lysine BioDex 1- + CO2
Name: lysine -> BioDex 1- + CO2
Description: Reaction transforming lysine into BioDex 1-, CO2
Type: state transition
Pathway Components: lysine - CadA - LdcI -> BioDex 1- + CO2
Components:
Function Name Type
product BioDex 1- simple_molecule
product CO2 simple_molecule
catalyzer CadA protein
catalyzer LdcI protein
reactant lysine simple_molecule
cadBA_mRNA LdcI
Name: cadBA_mRNA -> LdcI
Description: Translation of LdcI
Type: translation
Pathway Components: cadBA_mRNA -> LdcI
Components:
Function Name Type
product LdcI protein
reactant cadBA_mRNA RNA
slp-dctR_mRNA Slp
Name: slp-dctR_mRNA -> Slp
Description: Translation of Slp
Type: translation
Pathway Components: slp-dctR_mRNA -> Slp
Components:
Function Name Type
product Slp protein
reactant slp-dctR_mRNA RNA
slp-dctR_mRNA DctR
Name: slp-dctR_mRNA -> DctR
Description: Translation of DctR
Type: translation
Pathway Components: slp-dctR_mRNA -> DctR
Components:
Function Name Type
product DctR protein
reactant slp-dctR_mRNA RNA
gadAX_mRNA GadA
Name: gadAX_mRNA -> GadA
Description: Translation of GadA
Type: translation
Pathway Components: gadAX_mRNA -> GadA
Components:
Function Name Type
product GadA protein
reactant gadAX_mRNA RNA
GadA L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadA -> GABA + CO2
Components:
Function Name Type
product CO2 simple_molecule
product GABA simple_molecule
catalyzer GadA protein
reactant L-glutamate simple_molecule
gadAX_mRNA GadX
Name: gadAX_mRNA -> GadX
Description: Translation of GadX
Type: translation
Pathway Components: gadAX_mRNA -> GadX
Components:
Function Name Type
product GadX protein
reactant gadAX_mRNA RNA
aslB_mRNA AslB
Name: aslB_mRNA -> AslB
Description: Translation of AslB
Type: translation
Pathway Components: aslB_mRNA -> AslB
Components:
Function Name Type
product AslB protein
reactant aslB_mRNA RNA



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