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FliZ Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
RcsB gadBC_mRNA osmY pdeR CsgE flhDC_mRNA GadE CsgG flhDC CsgB CsgE L-glutamate HdeA L-glutamate_Ext FlhD RNA:GadF TolC HdeB CsgF osmY_mRNA FlhC YhiD CsgC MdtE gadEF-mdtEF_mRNA c-di-GMP GadC OsmY csgDEFG_mRNA mlrA gadEF-mdtEF CsgG hdeAB-yhiD GadE MdtF FlhD RcsB MdtE MlrA csgBAC GadB drug_Ext csgDEFG mlrA_mRNA MdtF CsgA_Ext FliZ 5'pGpG GABA_Ext GABA CO2 CsgA FlhC csgBAC_mRNA hdeAB-yhiD_mRNA PdeR pdeR_mRNA gadBC CsgD drug TolC


Gensor Unit       
Name: FliZ
Classification:
Groups: Transcription
Signal transduction mechanisms
Amino acid transport and metabolism
Defense mechanisms
Cell wall/membrane/envelope biogenesis
Gene Ontology Terms (GO): biological_process GO:1902475 - L-alpha-amino acid transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0006865 - amino acid transport
GO:1990000 - amyloid fibril formation
GO:0044780 - bacterial-type flagellum assembly
GO:0044781 - bacterial-type flagellum organization
Read more >
cellular_component GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0031246 - intrinsic component of periplasmic side of cell outer membrane
GO:0031226 - intrinsic component of plasma membrane
Read more >
molecular_function GO:0003677 - DNA binding
GO:0001216 - DNA-binding transcription activator activity
GO:0003700 - DNA-binding transcription factor activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0005525 - GTP binding
GO:0015179 - L-amino acid transmembrane transporter activity
GO:0015171 - amino acid transmembrane transporter activity
Read more >
Components:
  Function Name Type
  simple_molecule 5'pGpG simple_molecule
  simple_molecule CO2 simple_molecule
  simple_molecule CsgA simple_molecule
  simple_molecule CsgA_Ext simple_molecule
  protein CsgB protein
  protein CsgC protein
  protein CsgD protein
  protein CsgE protein
  complex CsgE-CsgG complex
  protein CsgF protein
  protein CsgG protein
  protein FlhC protein
  protein FlhD protein
  complex FlhD-FlhC complex
  protein FliZ protein
  simple_molecule GABA simple_molecule
  simple_molecule GABA_Ext simple_molecule
  protein GadB protein
  protein GadC protein
  protein GadE protein
  protein HdeA protein
  protein HdeB protein
  simple_molecule L-glutamate simple_molecule
  simple_molecule L-glutamate_Ext simple_molecule
  protein MdtE protein
  protein MdtF protein
  protein MlrA protein
  protein OsmY protein
  protein PdeR protein
  protein RNA:GadF protein
  protein RcsB protein
  complex RcsB-GadE complex
  protein TolC protein
  complex TolC-MdtE-MdtF complex
  protein YhiD protein
  simple_molecule c-di-GMP simple_molecule
  gene csgBAC gene
  RNA csgBAC_mRNA RNA
  gene csgDEFG gene
  RNA csgDEFG_mRNA RNA
  simple_molecule drug simple_molecule
  simple_molecule drug_Ext simple_molecule
  gene flhDC gene
  RNA flhDC_mRNA RNA
  gene gadBC gene
  RNA gadBC_mRNA RNA
  gene gadEF-mdtEF gene
  RNA gadEF-mdtEF_mRNA RNA
  gene hdeAB-yhiD gene
  RNA hdeAB-yhiD_mRNA RNA
  gene mlrA gene
  RNA mlrA_mRNA RNA
  gene osmY gene
  RNA osmY_mRNA RNA
  gene pdeR gene
  RNA pdeR_mRNA RNA


Reactions       
Showing 39 reactions
FliZ csgBAC csgBAC_mRNA
Name: csgBAC -> csgBAC_mRNA
Description: Transcription of transcription unit csgBAC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: csgBAC - FliZ -> csgBAC_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant csgBAC gene
product csgBAC_mRNA RNA
FliZ csgDEFG csgDEFG_mRNA
Name: csgDEFG -> csgDEFG_mRNA
Description: Transcription of transcription unit csgDEFG. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: csgDEFG - FliZ -> csgDEFG_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant csgDEFG gene
product csgDEFG_mRNA RNA
FliZ flhDC flhDC_mRNA
Name: flhDC -> flhDC_mRNA
Description: Transcription of transcription unit flhDC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: flhDC - FliZ -> flhDC_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant flhDC gene
product flhDC_mRNA RNA
FliZ gadBC gadBC_mRNA
Name: gadBC -> gadBC_mRNA
Description: Transcription of transcription unit gadBC. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: gadBC - FliZ -> gadBC_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant gadBC gene
product gadBC_mRNA RNA
FliZ gadEF-mdtEF gadEF-mdtEF_mRNA
Name: gadEF-mdtEF -> gadEF-mdtEF_mRNA
Description: Transcription of transcription unit gadEF-mdtEF. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: gadEF-mdtEF - FliZ -> gadEF-mdtEF_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant gadEF-mdtEF gene
product gadEF-mdtEF_mRNA RNA
FliZ hdeAB-yhiD hdeAB-yhiD_mRNA
Name: hdeAB-yhiD -> hdeAB-yhiD_mRNA
Description: Transcription of transcription unit hdeAB-yhiD. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: hdeAB-yhiD - FliZ -> hdeAB-yhiD_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant hdeAB-yhiD gene
product hdeAB-yhiD_mRNA RNA
FliZ mlrA mlrA_mRNA
Name: mlrA -> mlrA_mRNA
Description: Transcription of transcription unit mlrA. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: mlrA - FliZ -> mlrA_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant mlrA gene
product mlrA_mRNA RNA
FliZ osmY osmY_mRNA
Name: osmY -> osmY_mRNA
Description: Transcription of transcription unit osmY. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: osmY - FliZ -> osmY_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant osmY gene
product osmY_mRNA RNA
FliZ pdeR pdeR_mRNA
Name: pdeR -> pdeR_mRNA
Description: Transcription of transcription unit pdeR. Reaction inhibition by FliZ.
Type: transcription
Pathway Components: pdeR - FliZ -> pdeR_mRNA
Components:
Function Name Type
inhibitor FliZ protein
reactant pdeR gene
product pdeR_mRNA RNA
gadBC_mRNA GadB
Name: gadBC_mRNA -> GadB
Description: Translation of GadB
Type: translation
Pathway Components: gadBC_mRNA -> GadB
Components:
Function Name Type
product GadB protein
reactant gadBC_mRNA RNA
GadB L-glutamate GABA + CO2
Name: L-glutamate -> GABA + CO2
Description: Reaction transforming L-glutamate into GABA, CO2
Type: state transition
Pathway Components: L-glutamate - GadB -> GABA + CO2
Components:
Function Name Type
product CO2 simple_molecule
product GABA simple_molecule
catalyzer GadB protein
reactant L-glutamate simple_molecule
gadBC_mRNA GadC
Name: gadBC_mRNA -> GadC
Description: Translation of GadC
Type: translation
Pathway Components: gadBC_mRNA -> GadC
Components:
Function Name Type
product GadC protein
reactant gadBC_mRNA RNA
GadC L-glutamate_Ext + GABA_Ext L-glutamate + GABA
Name: L-glutamate_Ext + GABA_Ext -> L-glutamate + GABA
Description: Transport of L-glutamate_Ext, GABA_Ext through a bacterial membrane, leading to the presence of L-glutamate, GABA inside the cell.
Type: transport
Pathway Components: L-glutamate_Ext + GABA_Ext - GadC -> L-glutamate + GABA
Components:
Function Name Type
product GABA simple_molecule
reactant GABA_Ext simple_molecule
catalyzer GadC protein
product L-glutamate simple_molecule
reactant L-glutamate_Ext simple_molecule
csgDEFG_mRNA CsgD
Name: csgDEFG_mRNA -> CsgD
Description: Translation of CsgD
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgD
Components:
Function Name Type
product CsgD protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgE
Name: csgDEFG_mRNA -> CsgE
Description: Translation of CsgE
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgE
Components:
Function Name Type
product CsgE protein
reactant csgDEFG_mRNA RNA
CsgG + CsgE CsgE-CsgG
Name: CsgG + CsgE -> CsgE-CsgG
Description: Reaction transforming CsgG, CsgE into CsgE-CsgG
Type: state transition
Pathway Components: CsgG + CsgE -> CsgE-CsgG
Components:
Function Name Type
reactant CsgE protein
product CsgE-CsgG complex
reactant CsgG protein
CsgE-CsgG CsgA_Ext CsgA
Name: CsgA_Ext -> CsgA
Description: Transport of CsgA_Ext through a bacterial membrane, leading to the presence of CsgA inside the cell.
Type: transport
Pathway Components: CsgA_Ext - CsgE-CsgG -> CsgA
Components:
Function Name Type
product CsgA simple_molecule
reactant CsgA_Ext simple_molecule
catalyzer CsgE-CsgG complex
csgDEFG_mRNA CsgF
Name: csgDEFG_mRNA -> CsgF
Description: Translation of CsgF
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgF
Components:
Function Name Type
product CsgF protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgG
Name: csgDEFG_mRNA -> CsgG
Description: Translation of CsgG
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgG
Components:
Function Name Type
product CsgG protein
reactant csgDEFG_mRNA RNA
osmY_mRNA OsmY
Name: osmY_mRNA -> OsmY
Description: Translation of OsmY
Type: translation
Pathway Components: osmY_mRNA -> OsmY
Components:
Function Name Type
product OsmY protein
reactant osmY_mRNA RNA
csgBAC_mRNA CsgB
Name: csgBAC_mRNA -> CsgB
Description: Translation of CsgB
Type: translation
Pathway Components: csgBAC_mRNA -> CsgB
Components:
Function Name Type
product CsgB protein
reactant csgBAC_mRNA RNA
csgBAC_mRNA CsgA
Name: csgBAC_mRNA -> CsgA
Description: Translation of CsgA
Type: translation
Pathway Components: csgBAC_mRNA -> CsgA
Components:
Function Name Type
product CsgA simple_molecule
reactant csgBAC_mRNA RNA
csgBAC_mRNA CsgC
Name: csgBAC_mRNA -> CsgC
Description: Translation of CsgC
Type: translation
Pathway Components: csgBAC_mRNA -> CsgC
Components:
Function Name Type
product CsgC protein
reactant csgBAC_mRNA RNA
mlrA_mRNA MlrA
Name: mlrA_mRNA -> MlrA
Description: Translation of MlrA
Type: translation
Pathway Components: mlrA_mRNA -> MlrA
Components:
Function Name Type
product MlrA protein
reactant mlrA_mRNA RNA
flhDC_mRNA FlhD
Name: flhDC_mRNA -> FlhD
Description: Translation of FlhD
Type: translation
Pathway Components: flhDC_mRNA -> FlhD
Components:
Function Name Type
product FlhD protein
reactant flhDC_mRNA RNA
FlhD + FlhC FlhD-FlhC
Name: FlhD + FlhC -> FlhD-FlhC
Description: Reaction transforming FlhD, FlhC into FlhD-FlhC
Type: state transition
Pathway Components: FlhD + FlhC -> FlhD-FlhC
Components:
Function Name Type
reactant FlhC protein
reactant FlhD protein
product FlhD-FlhC complex
flhDC_mRNA FlhC
Name: flhDC_mRNA -> FlhC
Description: Translation of FlhC
Type: translation
Pathway Components: flhDC_mRNA -> FlhC
Components:
Function Name Type
product FlhC protein
reactant flhDC_mRNA RNA
hdeAB-yhiD_mRNA HdeA
Name: hdeAB-yhiD_mRNA -> HdeA
Description: Translation of HdeA
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeA
Components:
Function Name Type
product HdeA protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA HdeB
Name: hdeAB-yhiD_mRNA -> HdeB
Description: Translation of HdeB
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> HdeB
Components:
Function Name Type
product HdeB protein
reactant hdeAB-yhiD_mRNA RNA
hdeAB-yhiD_mRNA YhiD
Name: hdeAB-yhiD_mRNA -> YhiD
Description: Translation of YhiD
Type: translation
Pathway Components: hdeAB-yhiD_mRNA -> YhiD
Components:
Function Name Type
product YhiD protein
reactant hdeAB-yhiD_mRNA RNA
gadEF-mdtEF_mRNA GadE
Name: gadEF-mdtEF_mRNA -> GadE
Description: Translation of GadE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> GadE
Components:
Function Name Type
product GadE protein
reactant gadEF-mdtEF_mRNA RNA
GadE + RcsB RcsB-GadE
Name: GadE + RcsB -> RcsB-GadE
Description: Reaction transforming GadE, RcsB into RcsB-GadE
Type: state transition
Pathway Components: GadE + RcsB -> RcsB-GadE
Components:
Function Name Type
reactant GadE protein
reactant RcsB protein
product RcsB-GadE complex
gadEF-mdtEF_mRNA RNA:GadF
Name: gadEF-mdtEF_mRNA -> RNA:GadF
Description: Translation of RNA:GadF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> RNA:GadF
Components:
Function Name Type
product RNA:GadF protein
reactant gadEF-mdtEF_mRNA RNA
gadEF-mdtEF_mRNA MdtE
Name: gadEF-mdtEF_mRNA -> MdtE
Description: Translation of MdtE
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtE
Components:
Function Name Type
product MdtE protein
reactant gadEF-mdtEF_mRNA RNA
MdtE + TolC + MdtF TolC-MdtE-MdtF
Name: MdtE + TolC + MdtF -> TolC-MdtE-MdtF
Description: Reaction transforming MdtE, TolC, MdtF into TolC-MdtE-MdtF
Type: state transition
Pathway Components: MdtE + TolC + MdtF -> TolC-MdtE-MdtF
Components:
Function Name Type
reactant MdtE protein
reactant MdtF protein
reactant TolC protein
product TolC-MdtE-MdtF complex
TolC-MdtE-MdtF drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - TolC-MdtE-MdtF -> drug
Components:
Function Name Type
catalyzer TolC-MdtE-MdtF complex
product drug simple_molecule
reactant drug_Ext simple_molecule
gadEF-mdtEF_mRNA MdtF
Name: gadEF-mdtEF_mRNA -> MdtF
Description: Translation of MdtF
Type: translation
Pathway Components: gadEF-mdtEF_mRNA -> MdtF
Components:
Function Name Type
product MdtF protein
reactant gadEF-mdtEF_mRNA RNA
pdeR_mRNA PdeR
Name: pdeR_mRNA -> PdeR
Description: Translation of PdeR
Type: translation
Pathway Components: pdeR_mRNA -> PdeR
Components:
Function Name Type
product PdeR protein
reactant pdeR_mRNA RNA
PdeR c-di-GMP 5'pGpG
Name: c-di-GMP -> 5'pGpG
Description: Reaction transforming c-di-GMP into 5'pGpG
Type: state transition
Pathway Components: c-di-GMP - PdeR -> 5'pGpG
Components:
Function Name Type
product 5'pGpG simple_molecule
catalyzer PdeR protein
reactant c-di-GMP simple_molecule



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