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FeaR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
FeaR feaB RCH2NH2 phenethylamine feaB_mRNA ammonium TynA oxygen tynA phenylacetate primary amine oxopropanal tynA_mRNA perhydrol FeaB aminoacetone hyacinthin oxygen


Gensor Unit       
Name: FeaR
Classification:
Groups: Secondary metabolites biosynthesis, transport and catabolism
Energy production and conversion
Gene Ontology Terms (GO): biological_process GO:0046196 - 4-nitrophenol catabolic process
GO:0006559 - L-phenylalanine catabolic process
GO:0009435 - NAD biosynthetic process
GO:0009308 - amine metabolic process
GO:0008152 - metabolic process
GO:0055114 - oxidation-reduction process
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cellular_component GO:0005829 - cytosol
GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
molecular_function GO:0047106 - 4-hydroxyphenylacetaldehyde dehydrogenase activity
GO:0052595 - aliphatic-amine oxidase activity
GO:0052594 - aminoacetone:oxygen oxidoreductase(deaminating) activity
GO:0005509 - calcium ion binding
GO:0005507 - copper ion binding
GO:0046872 - metal ion binding
GO:0016491 - oxidoreductase activity
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Components:
  Function Name Type
  protein FeaB protein
  protein FeaR protein
  simple_molecule RCH2NH2 simple_molecule
  simple_molecule RCHO simple_molecule
  protein TynA protein
  simple_molecule aminoacetone simple_molecule
  simple_molecule ammonium simple_molecule
  gene feaB gene
  RNA feaB_mRNA RNA
  simple_molecule hyacinthin simple_molecule
  simple_molecule oxopropanal simple_molecule
  simple_molecule oxygen simple_molecule
  simple_molecule perhydrol simple_molecule
  simple_molecule phenethylamine simple_molecule
  simple_molecule phenylacetate simple_molecule
  simple_molecule primary amine simple_molecule
  gene tynA gene
  RNA tynA_mRNA RNA


Reactions       
Showing 9 reactions
FeaR feaB feaB_mRNA
Name: feaB -> feaB_mRNA
Description: Transcription of transcription unit feaB. Reaction activation by FeaR.
Type: transcription
Pathway Components: feaB - FeaR -> feaB_mRNA
Components:
Function Name Type
activator FeaR protein
reactant feaB gene
product feaB_mRNA RNA
FeaR tynA tynA_mRNA
Name: tynA -> tynA_mRNA
Description: Transcription of transcription unit tynA. Reaction activation by FeaR.
Type: transcription
Pathway Components: tynA - FeaR -> tynA_mRNA
Components:
Function Name Type
activator FeaR protein
reactant tynA gene
product tynA_mRNA RNA
tynA_mRNA TynA
Name: tynA_mRNA -> TynA
Description: Translation of TynA
Type: translation
Pathway Components: tynA_mRNA -> TynA
Components:
Function Name Type
product TynA protein
reactant tynA_mRNA RNA
TynA primary amine + oxygen perhydrol + ammonium + RCHO
Name: primary amine + oxygen -> perhydrol + ammonium + RCHO
Description: Reaction transforming primary amine, oxygen into perhydrol, ammonium , RCHO
Type: state transition
Pathway Components: primary amine + oxygen - TynA -> perhydrol + ammonium + RCHO
Components:
Function Name Type
product RCHO simple_molecule
catalyzer TynA protein
product ammonium simple_molecule
reactant oxygen simple_molecule
product perhydrol simple_molecule
reactant primary amine simple_molecule
TynA phenethylamine + oxygen hyacinthin + perhydrol + ammonium
Name: phenethylamine + oxygen -> hyacinthin + perhydrol + ammonium
Description: Reaction transforming phenethylamine, oxygen into hyacinthin, perhydrol , ammonium
Type: state transition
Pathway Components: phenethylamine + oxygen - TynA -> hyacinthin + perhydrol + ammonium
Components:
Function Name Type
catalyzer TynA protein
product ammonium simple_molecule
product hyacinthin simple_molecule
reactant oxygen simple_molecule
product perhydrol simple_molecule
reactant phenethylamine simple_molecule
TynA aminoacetone + oxygen oxopropanal + perhydrol + ammonium
Name: aminoacetone + oxygen -> oxopropanal + perhydrol + ammonium
Description: Reaction transforming aminoacetone, oxygen into oxopropanal, perhydrol , ammonium
Type: state transition
Pathway Components: aminoacetone + oxygen - TynA -> oxopropanal + perhydrol + ammonium
Components:
Function Name Type
catalyzer TynA protein
reactant aminoacetone simple_molecule
product ammonium simple_molecule
product oxopropanal simple_molecule
reactant oxygen simple_molecule
product perhydrol simple_molecule
TynA RCH2NH2 + oxygen perhydrol + ammonium + RCHO
Name: RCH2NH2 + oxygen -> perhydrol + ammonium + RCHO
Description: Reaction transforming RCH2NH2, oxygen into perhydrol, ammonium , RCHO
Type: state transition
Pathway Components: RCH2NH2 + oxygen - TynA -> perhydrol + ammonium + RCHO
Components:
Function Name Type
reactant RCH2NH2 simple_molecule
product RCHO simple_molecule
catalyzer TynA protein
product ammonium simple_molecule
reactant oxygen simple_molecule
product perhydrol simple_molecule
feaB_mRNA FeaB
Name: feaB_mRNA -> FeaB
Description: Translation of FeaB
Type: translation
Pathway Components: feaB_mRNA -> FeaB
Components:
Function Name Type
product FeaB protein
reactant feaB_mRNA RNA
FeaB hyacinthin hyacinthin phenylacetate
Name: hyacinthin -> phenylacetate
Description: Reaction transforming hyacinthin into phenylacetate
Type: state transition
Pathway Components: hyacinthin - FeaB - hyacinthin -> phenylacetate
Components:
Function Name Type
catalyzer FeaB protein
inhibitor hyacinthin simple_molecule
reactant hyacinthin simple_molecule
product phenylacetate simple_molecule



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