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CspA Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
hns_mRNA CspA phosphate GyrA gyrA GyrA GyrB GyrB Hns gyrA_mRNA negatively supercoiled DNA double stranded DNA hns


Gensor Unit       
Name: CspA
Classification:
Groups: Transcription
Replication, recombination and repair
Gene Ontology Terms (GO): biological_process GO:0006259 - DNA metabolic process
GO:0006265 - DNA topological change
GO:1900232 - negative regulation of single-species biofilm formation on inanimate substrate
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0006355 - regulation of transcription, DNA-templated
GO:0006417 - regulation of translation
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cellular_component GO:0009330 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex
GO:0005694 - chromosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005622 - intracellular anatomical structure
GO:0009295 - nucleoid
GO:0032993 - protein-DNA complex
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molecular_function GO:0005524 - ATP binding
GO:0008094 - ATP-dependent activity, acting on DNA
GO:0003677 - DNA binding
GO:0034335 - DNA negative supercoiling activity
GO:0003916 - DNA topoisomerase activity
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0001217 - DNA-binding transcription repressor activity
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Components:
  Function Name Type
  protein CspA protein
  protein GyrA protein
  complex GyrA-GyrB complex
  protein GyrB protein
  protein Hns protein
  simple_molecule double stranded DNA simple_molecule
  gene gyrA gene
  RNA gyrA_mRNA RNA
  gene hns gene
  RNA hns_mRNA RNA
  simple_molecule negatively supercoiled DNA simple_molecule
  simple_molecule phosphate simple_molecule


Reactions       
Showing 6 reactions
CspA gyrA gyrA_mRNA
Name: gyrA -> gyrA_mRNA
Description: Transcription of transcription unit gyrA. Reaction activation by CspA.
Type: transcription
Pathway Components: gyrA - CspA -> gyrA_mRNA
Components:
Function Name Type
activator CspA protein
reactant gyrA gene
product gyrA_mRNA RNA
CspA hns hns_mRNA
Name: hns -> hns_mRNA
Description: Transcription of transcription unit hns. Reaction activation by CspA.
Type: transcription
Pathway Components: hns - CspA -> hns_mRNA
Components:
Function Name Type
activator CspA protein
reactant hns gene
product hns_mRNA RNA
gyrA_mRNA GyrA
Name: gyrA_mRNA -> GyrA
Description: Translation of GyrA
Type: translation
Pathway Components: gyrA_mRNA -> GyrA
Components:
Function Name Type
product GyrA protein
reactant gyrA_mRNA RNA
GyrB + GyrA GyrA-GyrB
Name: GyrB + GyrA -> GyrA-GyrB
Description: Reaction transforming GyrB, GyrA into GyrA-GyrB
Type: state transition
Pathway Components: GyrB + GyrA -> GyrA-GyrB
Components:
Function Name Type
reactant GyrA protein
product GyrA-GyrB complex
reactant GyrB protein
GyrA-GyrB double stranded DNA negatively supercoiled DNA + phosphate
Name: double stranded DNA -> negatively supercoiled DNA + phosphate
Description: Reaction transforming double stranded DNA into negatively supercoiled DNA, phosphate
Type: state transition
Pathway Components: double stranded DNA - GyrA-GyrB -> negatively supercoiled DNA + phosphate
Components:
Function Name Type
catalyzer GyrA-GyrB complex
reactant double stranded DNA simple_molecule
product negatively supercoiled DNA simple_molecule
product phosphate simple_molecule
hns_mRNA Hns
Name: hns_mRNA -> Hns
Description: Translation of Hns
Type: translation
Pathway Components: hns_mRNA -> Hns
Components:
Function Name Type
product Hns protein
reactant hns_mRNA RNA
R1 R2 R3 R4 R5 R6



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