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Cbl Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
oxygen Cbl sulfite succinate ssuEADCB glycoaldehyde thiosulfate thiosulfate flavin mononucleotide Reduced FMN butanal ketoglutarate 3-morpholinopropanal TauA TauC MOPS taufon CO2 aliphatic sulfonate_Ext aliphatic sulfonate SsuC SsuE SsuA TauB aminoacetaldehyde tauABCD butanesulfonate Cbl ssuEADCB_mRNA taufon_Ext RCHO TauA adenylyl-sulfate SsuC tauABCD_mRNA SsuB TauB TauD Cbl alkanesulfonate adenylyl-sulfate isethionate SsuB TauC SsuD SsuA oxygen oxygen oxygen sulfite sulfite sulfite Reduced FMN Reduced FMN


Gensor Unit       
Name: Cbl
Classification:
Groups: Inorganic ion transport and metabolism
Secondary metabolites biosynthesis, transport and catabolism
Energy production and conversion
Coenzyme transport and metabolism
Gene Ontology Terms (GO): biological_process GO:0046306 - alkanesulfonate catabolic process
GO:0042918 - alkanesulfonate transport
GO:0098656 - anion transmembrane transport
GO:0006820 - anion transport
GO:0006974 - cellular response to DNA damage stimulus
GO:0009970 - cellular response to sulfate starvation
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cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
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molecular_function GO:0005524 - ATP binding
GO:0016887 - ATPase activity
GO:0015411 - ATPase-coupled taurine transporter activity
GO:0042626 - ATPase-coupled transmembrane transporter activity
GO:0052873 - FMN reductase (NADPH) activity
GO:0008752 - FMN reductase activity
GO:0031418 - L-ascorbic acid binding
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Components:
  Function Name Type
  simple_molecule 3-morpholinopropanal simple_molecule
  simple_molecule CO2 simple_molecule
  protein Cbl protein
  complex Cbl-adenylyl-sulfate complex
  complex Cbl-thiosulfate complex
  simple_molecule MOPS simple_molecule
  simple_molecule RCHO simple_molecule
  simple_molecule Reduced FMN simple_molecule
  protein SsuA protein
  complex SsuA-SsuC-SsuB complex
  protein SsuB protein
  protein SsuC protein
  protein SsuD protein
  protein SsuE protein
  protein TauA protein
  complex TauA-TauC-TauB complex
  protein TauB protein
  protein TauC protein
  protein TauD protein
  simple_molecule adenylyl-sulfate simple_molecule
  simple_molecule aliphatic sulfonate simple_molecule
  simple_molecule aliphatic sulfonate_Ext simple_molecule
  simple_molecule alkanesulfonate simple_molecule
  simple_molecule aminoacetaldehyde simple_molecule
  simple_molecule butanal simple_molecule
  simple_molecule butanesulfonate simple_molecule
  simple_molecule flavin mononucleotide simple_molecule
  simple_molecule glycoaldehyde simple_molecule
  simple_molecule isethionate simple_molecule
  simple_molecule ketoglutarate simple_molecule
  simple_molecule oxygen simple_molecule
  gene ssuEADCB gene
  RNA ssuEADCB_mRNA RNA
  simple_molecule succinate simple_molecule
  simple_molecule sulfite simple_molecule
  gene tauABCD gene
  RNA tauABCD_mRNA RNA
  simple_molecule taufon simple_molecule
  simple_molecule taufon_Ext simple_molecule
  simple_molecule thiosulfate simple_molecule


Reactions       
Showing 23 reactions
Cbl ssuEADCB ssuEADCB_mRNA
Name: ssuEADCB -> ssuEADCB_mRNA
Description: Transcription of transcription unit ssuEADCB. Reaction activation by Cbl.
Type: transcription
Pathway Components: ssuEADCB - Cbl -> ssuEADCB_mRNA
Components:
Function Name Type
activator Cbl protein
reactant ssuEADCB gene
product ssuEADCB_mRNA RNA
Cbl tauABCD tauABCD_mRNA
Name: tauABCD -> tauABCD_mRNA
Description: Transcription of transcription unit tauABCD. Reaction activation by Cbl.
Type: transcription
Pathway Components: tauABCD - Cbl -> tauABCD_mRNA
Components:
Function Name Type
activator Cbl protein
reactant tauABCD gene
product tauABCD_mRNA RNA
adenylyl-sulfate + Cbl Cbl-adenylyl-sulfate
Name: adenylyl-sulfate + Cbl -> Cbl-adenylyl-sulfate
Description: Reaction transforming adenylyl-sulfate, Cbl into Cbl-adenylyl-sulfate
Type: state transition
Pathway Components: adenylyl-sulfate + Cbl -> Cbl-adenylyl-sulfate
Components:
Function Name Type
reactant Cbl protein
product Cbl-adenylyl-sulfate complex
reactant adenylyl-sulfate simple_molecule
thiosulfate + Cbl Cbl-thiosulfate
Name: thiosulfate + Cbl -> Cbl-thiosulfate
Description: Reaction transforming thiosulfate, Cbl into Cbl-thiosulfate
Type: state transition
Pathway Components: thiosulfate + Cbl -> Cbl-thiosulfate
Components:
Function Name Type
reactant Cbl protein
product Cbl-thiosulfate complex
reactant thiosulfate simple_molecule
ssuEADCB_mRNA SsuE
Name: ssuEADCB_mRNA -> SsuE
Description: Translation of SsuE
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuE
Components:
Function Name Type
product SsuE protein
reactant ssuEADCB_mRNA RNA
SsuE flavin mononucleotide Reduced FMN
Name: flavin mononucleotide -> Reduced FMN
Description: Reaction transforming flavin mononucleotide into Reduced FMN
Type: state transition
Pathway Components: flavin mononucleotide - SsuE -> Reduced FMN
Components:
Function Name Type
product Reduced FMN simple_molecule
catalyzer SsuE protein
reactant flavin mononucleotide simple_molecule
ssuEADCB_mRNA SsuA
Name: ssuEADCB_mRNA -> SsuA
Description: Translation of SsuA
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuA
Components:
Function Name Type
product SsuA protein
reactant ssuEADCB_mRNA RNA
SsuC + SsuA + SsuB SsuA-SsuC-SsuB
Name: SsuC + SsuA + SsuB -> SsuA-SsuC-SsuB
Description: Reaction transforming SsuC, SsuA, SsuB into SsuA-SsuC-SsuB
Type: state transition
Pathway Components: SsuC + SsuA + SsuB -> SsuA-SsuC-SsuB
Components:
Function Name Type
reactant SsuA protein
product SsuA-SsuC-SsuB complex
reactant SsuB protein
reactant SsuC protein
SsuA-SsuC-SsuB aliphatic sulfonate_Ext aliphatic sulfonate
Name: aliphatic sulfonate_Ext -> aliphatic sulfonate
Description: Transport of aliphatic sulfonate_Ext through a bacterial membrane, leading to the presence of aliphatic sulfonate inside the cell.
Type: transport
Pathway Components: aliphatic sulfonate_Ext - SsuA-SsuC-SsuB -> aliphatic sulfonate
Components:
Function Name Type
catalyzer SsuA-SsuC-SsuB complex
product aliphatic sulfonate simple_molecule
reactant aliphatic sulfonate_Ext simple_molecule
ssuEADCB_mRNA SsuD
Name: ssuEADCB_mRNA -> SsuD
Description: Translation of SsuD
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuD
Components:
Function Name Type
product SsuD protein
reactant ssuEADCB_mRNA RNA
SsuD alkanesulfonate + Reduced FMN + oxygen flavin mononucleotide + sulfite + RCHO
Name: alkanesulfonate + Reduced FMN + oxygen -> flavin mononucleotide + sulfite + RCHO
Description: Reaction transforming alkanesulfonate, Reduced FMN, oxygen into flavin mononucleotide, sulfite , RCHO
Type: state transition
Pathway Components: alkanesulfonate + Reduced FMN + oxygen - SsuD -> flavin mononucleotide + sulfite + RCHO
Components:
Function Name Type
product RCHO simple_molecule
reactant Reduced FMN simple_molecule
catalyzer SsuD protein
reactant alkanesulfonate simple_molecule
product flavin mononucleotide simple_molecule
reactant oxygen simple_molecule
product sulfite simple_molecule
SsuD Reduced FMN + oxygen + MOPS Products
Name: Reduced FMN + oxygen + MOPS -> flavin mononucleotide + 3-morpholinopropanal + sulfite
Description: Reaction transforming Reduced FMN, oxygen, MOPS into flavin mononucleotide, 3-morpholinopropanal , sulfite
Type: state transition
Pathway Components: Reduced FMN + oxygen + MOPS - SsuD -> flavin mononucleotide + 3-morpholinopropanal + sulfite
Components:
Function Name Type
product 3-morpholinopropanal simple_molecule
reactant MOPS simple_molecule
reactant Reduced FMN simple_molecule
catalyzer SsuD protein
product flavin mononucleotide simple_molecule
reactant oxygen simple_molecule
product sulfite simple_molecule
SsuD butanesulfonate + Reduced FMN + oxygen flavin mononucleotide + sulfite + butanal
Name: butanesulfonate + Reduced FMN + oxygen -> flavin mononucleotide + sulfite + butanal
Description: Reaction transforming butanesulfonate, Reduced FMN, oxygen into flavin mononucleotide, sulfite , butanal
Type: state transition
Pathway Components: butanesulfonate + Reduced FMN + oxygen - SsuD -> flavin mononucleotide + sulfite + butanal
Components:
Function Name Type
reactant Reduced FMN simple_molecule
catalyzer SsuD protein
product butanal simple_molecule
reactant butanesulfonate simple_molecule
product flavin mononucleotide simple_molecule
reactant oxygen simple_molecule
product sulfite simple_molecule
SsuD Reduced FMN + isethionate + oxygen flavin mononucleotide + glycoaldehyde + sulfite
Name: Reduced FMN + isethionate + oxygen -> flavin mononucleotide + glycoaldehyde + sulfite
Description: Reaction transforming Reduced FMN, isethionate, oxygen into flavin mononucleotide, glycoaldehyde , sulfite
Type: state transition
Pathway Components: Reduced FMN + isethionate + oxygen - SsuD -> flavin mononucleotide + glycoaldehyde + sulfite
Components:
Function Name Type
reactant Reduced FMN simple_molecule
catalyzer SsuD protein
product flavin mononucleotide simple_molecule
product glycoaldehyde simple_molecule
reactant isethionate simple_molecule
reactant oxygen simple_molecule
product sulfite simple_molecule
ssuEADCB_mRNA SsuC
Name: ssuEADCB_mRNA -> SsuC
Description: Translation of SsuC
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuC
Components:
Function Name Type
product SsuC protein
reactant ssuEADCB_mRNA RNA
ssuEADCB_mRNA SsuB
Name: ssuEADCB_mRNA -> SsuB
Description: Translation of SsuB
Type: translation
Pathway Components: ssuEADCB_mRNA -> SsuB
Components:
Function Name Type
product SsuB protein
reactant ssuEADCB_mRNA RNA
tauABCD_mRNA TauA
Name: tauABCD_mRNA -> TauA
Description: Translation of TauA
Type: translation
Pathway Components: tauABCD_mRNA -> TauA
Components:
Function Name Type
product TauA protein
reactant tauABCD_mRNA RNA
TauB + TauA + TauC TauA-TauC-TauB
Name: TauB + TauA + TauC -> TauA-TauC-TauB
Description: Reaction transforming TauB, TauA, TauC into TauA-TauC-TauB
Type: state transition
Pathway Components: TauB + TauA + TauC -> TauA-TauC-TauB
Components:
Function Name Type
reactant TauA protein
product TauA-TauC-TauB complex
reactant TauB protein
reactant TauC protein
TauA-TauC-TauB taufon_Ext taufon
Name: taufon_Ext -> taufon
Description: Transport of taufon_Ext through a bacterial membrane, leading to the presence of taufon inside the cell.
Type: transport
Pathway Components: taufon_Ext - TauA-TauC-TauB -> taufon
Components:
Function Name Type
catalyzer TauA-TauC-TauB complex
product taufon simple_molecule
reactant taufon_Ext simple_molecule
tauABCD_mRNA TauB
Name: tauABCD_mRNA -> TauB
Description: Translation of TauB
Type: translation
Pathway Components: tauABCD_mRNA -> TauB
Components:
Function Name Type
product TauB protein
reactant tauABCD_mRNA RNA
tauABCD_mRNA TauC
Name: tauABCD_mRNA -> TauC
Description: Translation of TauC
Type: translation
Pathway Components: tauABCD_mRNA -> TauC
Components:
Function Name Type
product TauC protein
reactant tauABCD_mRNA RNA
tauABCD_mRNA TauD
Name: tauABCD_mRNA -> TauD
Description: Translation of TauD
Type: translation
Pathway Components: tauABCD_mRNA -> TauD
Components:
Function Name Type
product TauD protein
reactant tauABCD_mRNA RNA
TauD ketoglutarate + oxygen + taufon aminoacetaldehyde + succinate + sulfite + CO2
Name: ketoglutarate + oxygen + taufon -> aminoacetaldehyde + succinate + sulfite + CO2
Description: Reaction transforming ketoglutarate, oxygen, taufon into aminoacetaldehyde, succinate , sulfite , CO2
Type: state transition
Pathway Components: ketoglutarate + oxygen + taufon - TauD -> aminoacetaldehyde + succinate + sulfite + CO2
Components:
Function Name Type
product CO2 simple_molecule
catalyzer TauD protein
product aminoacetaldehyde simple_molecule
reactant ketoglutarate simple_molecule
reactant oxygen simple_molecule
product succinate simple_molecule
product sulfite simple_molecule
reactant taufon simple_molecule



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