RegulonDB RegulonDB

BasR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
CsgE phosphate qseBC_mRNA YrbL CsgA fimB_mRNA FimB dgkA cspI BasR phosphatidate CspI D-1,2-diglyceride fimB cspI_mRNA pyrroline 5-carboxylate proline CsgG putA_mRNA putA QseB DgkA TomB L-glutamate phosphate CsgA_Ext yrbL_mRNA CsgF QseC qseBC dgkA_mRNA yrbL tomB-hha_mRNA Hha YgiY CsgD CsgE CsgG ubiquinone PutA BasR csgDEFG glutamate-semialdehyde csgDEFG_mRNA ubiquinol tomB-hha


Gensor Unit       
Name: BasR
Signal name: high Fe(III).
Classification:
Groups: Lipid transport and metabolism
Transcription
Replication, recombination and repair
Signal transduction mechanisms
Amino acid transport and metabolism
Cell wall/membrane/envelope biogenesis
Gene Ontology Terms (GO): biological_process GO:0015074 - DNA integration
GO:0006310 - DNA recombination
GO:0022610 - biological adhesion
GO:0006974 - cellular response to DNA damage stimulus
GO:0008610 - lipid biosynthetic process
GO:0006629 - lipid metabolic process
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cellular_component GO:0009279 - cell outer membrane
GO:0005737 - cytoplasm
GO:0009898 - cytoplasmic side of plasma membrane
GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005622 - intracellular anatomical structure
GO:0031246 - intrinsic component of periplasmic side of cell outer membrane
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molecular_function GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0005524 - ATP binding
GO:0003677 - DNA binding
GO:0001216 - DNA-binding transcription activator activity
GO:0003700 - DNA-binding transcription factor activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0000986 - bacterial-type cis-regulatory region sequence-specific DNA binding
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Components:
  Function Name Type
  protein BasR protein
  complex BasR-phosphate complex
  simple_molecule CsgA simple_molecule
  simple_molecule CsgA_Ext simple_molecule
  protein CsgD protein
  protein CsgE protein
  complex CsgE-CsgG complex
  protein CsgF protein
  protein CsgG protein
  protein CspI protein
  simple_molecule D-1,2-diglyceride simple_molecule
  protein DgkA protein
  protein FimB protein
  protein Hha protein
  simple_molecule L-glutamate simple_molecule
  protein PutA protein
  protein QseB protein
  protein QseC protein
  protein TomB protein
  protein YgiY protein
  protein YrbL protein
  gene csgDEFG gene
  RNA csgDEFG_mRNA RNA
  gene cspI gene
  RNA cspI_mRNA RNA
  gene dgkA gene
  RNA dgkA_mRNA RNA
  gene fimB gene
  RNA fimB_mRNA RNA
  simple_molecule glutamate-semialdehyde simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule phosphatidate simple_molecule
  simple_molecule proline simple_molecule
  gene putA gene
  RNA putA_mRNA RNA
  simple_molecule pyrroline 5-carboxylate simple_molecule
  gene qseBC gene
  RNA qseBC_mRNA RNA
  gene tomB-hha gene
  RNA tomB-hha_mRNA RNA
  simple_molecule ubiquinol simple_molecule
  simple_molecule ubiquinone simple_molecule
  gene yrbL gene
  RNA yrbL_mRNA RNA


Reactions       
Showing 29 reactions
phosphate + BasR BasR-phosphate
Name: phosphate + BasR -> BasR-phosphate
Description: Reaction transforming phosphate, BasR into BasR-phosphate
Type: state transition
Pathway Components: phosphate + BasR -> BasR-phosphate
Components:
Function Name Type
reactant BasR protein
product BasR-phosphate complex
reactant phosphate simple_molecule
BasR-phosphate csgDEFG csgDEFG_mRNA
Name: csgDEFG -> csgDEFG_mRNA
Description: Transcription of transcription unit csgDEFG. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: csgDEFG - BasR-phosphate -> csgDEFG_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant csgDEFG gene
product csgDEFG_mRNA RNA
BasR-phosphate cspI cspI_mRNA
Name: cspI -> cspI_mRNA
Description: Transcription of transcription unit cspI. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: cspI - BasR-phosphate -> cspI_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant cspI gene
product cspI_mRNA RNA
BasR-phosphate dgkA dgkA_mRNA
Name: dgkA -> dgkA_mRNA
Description: Transcription of transcription unit dgkA. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: dgkA - BasR-phosphate -> dgkA_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant dgkA gene
product dgkA_mRNA RNA
BasR-phosphate fimB fimB_mRNA
Name: fimB -> fimB_mRNA
Description: Transcription of transcription unit fimB. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: fimB - BasR-phosphate -> fimB_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant fimB gene
product fimB_mRNA RNA
BasR-phosphate qseBC qseBC_mRNA
Name: qseBC -> qseBC_mRNA
Description: Transcription of transcription unit qseBC. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: qseBC - BasR-phosphate -> qseBC_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant qseBC gene
product qseBC_mRNA RNA
BasR-phosphate tomB-hha tomB-hha_mRNA
Name: tomB-hha -> tomB-hha_mRNA
Description: Transcription of transcription unit tomB-hha. Reaction activation by BasR-phosphate.
Type: transcription
Pathway Components: tomB-hha - BasR-phosphate -> tomB-hha_mRNA
Components:
Function Name Type
activator BasR-phosphate complex
reactant tomB-hha gene
product tomB-hha_mRNA RNA
BasR-phosphate putA putA_mRNA
Name: putA -> putA_mRNA
Description: Transcription of transcription unit putA. Reaction inhibition by BasR-phosphate.
Type: transcription
Pathway Components: putA - BasR-phosphate -> putA_mRNA
Components:
Function Name Type
inhibitor BasR-phosphate complex
reactant putA gene
product putA_mRNA RNA
BasR-phosphate yrbL yrbL_mRNA
Name: yrbL -> yrbL_mRNA
Description: Transcription of transcription unit yrbL. Reaction inhibition by BasR-phosphate.
Type: transcription
Pathway Components: yrbL - BasR-phosphate -> yrbL_mRNA
Components:
Function Name Type
inhibitor BasR-phosphate complex
reactant yrbL gene
product yrbL_mRNA RNA
csgDEFG_mRNA CsgD
Name: csgDEFG_mRNA -> CsgD
Description: Translation of CsgD
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgD
Components:
Function Name Type
product CsgD protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgE
Name: csgDEFG_mRNA -> CsgE
Description: Translation of CsgE
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgE
Components:
Function Name Type
product CsgE protein
reactant csgDEFG_mRNA RNA
CsgG + CsgE CsgE-CsgG
Name: CsgG + CsgE -> CsgE-CsgG
Description: Reaction transforming CsgG, CsgE into CsgE-CsgG
Type: state transition
Pathway Components: CsgG + CsgE -> CsgE-CsgG
Components:
Function Name Type
reactant CsgE protein
product CsgE-CsgG complex
reactant CsgG protein
CsgE-CsgG CsgA_Ext CsgA
Name: CsgA_Ext -> CsgA
Description: Transport of CsgA_Ext through a bacterial membrane, leading to the presence of CsgA inside the cell.
Type: transport
Pathway Components: CsgA_Ext - CsgE-CsgG -> CsgA
Components:
Function Name Type
product CsgA simple_molecule
reactant CsgA_Ext simple_molecule
catalyzer CsgE-CsgG complex
csgDEFG_mRNA CsgF
Name: csgDEFG_mRNA -> CsgF
Description: Translation of CsgF
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgF
Components:
Function Name Type
product CsgF protein
reactant csgDEFG_mRNA RNA
csgDEFG_mRNA CsgG
Name: csgDEFG_mRNA -> CsgG
Description: Translation of CsgG
Type: translation
Pathway Components: csgDEFG_mRNA -> CsgG
Components:
Function Name Type
product CsgG protein
reactant csgDEFG_mRNA RNA
dgkA_mRNA DgkA
Name: dgkA_mRNA -> DgkA
Description: Translation of DgkA
Type: translation
Pathway Components: dgkA_mRNA -> DgkA
Components:
Function Name Type
product DgkA protein
reactant dgkA_mRNA RNA
D-1,2-diglyceride DgkA D-1,2-diglyceride phosphatidate
Name: D-1,2-diglyceride -> phosphatidate
Description: Reaction transforming D-1,2-diglyceride into phosphatidate
Type: state transition
Pathway Components: D-1,2-diglyceride - DgkA - D-1,2-diglyceride -> phosphatidate
Components:
Function Name Type
inhibitor D-1,2-diglyceride simple_molecule
reactant D-1,2-diglyceride simple_molecule
catalyzer DgkA protein
product phosphatidate simple_molecule
qseBC_mRNA QseB
Name: qseBC_mRNA -> QseB
Description: Translation of QseB
Type: translation
Pathway Components: qseBC_mRNA -> QseB
Components:
Function Name Type
product QseB protein
reactant qseBC_mRNA RNA
qseBC_mRNA QseC
Name: qseBC_mRNA -> QseC
Description: Translation of QseC
Type: translation
Pathway Components: qseBC_mRNA -> QseC
Components:
Function Name Type
product QseC protein
reactant qseBC_mRNA RNA
qseBC_mRNA YgiY
Name: qseBC_mRNA -> YgiY
Description: Translation of YgiY
Type: translation
Pathway Components: qseBC_mRNA -> YgiY
Components:
Function Name Type
product YgiY protein
reactant qseBC_mRNA RNA
yrbL_mRNA YrbL
Name: yrbL_mRNA -> YrbL
Description: Translation of YrbL
Type: translation
Pathway Components: yrbL_mRNA -> YrbL
Components:
Function Name Type
product YrbL protein
reactant yrbL_mRNA RNA
putA_mRNA PutA
Name: putA_mRNA -> PutA
Description: Translation of PutA
Type: translation
Pathway Components: putA_mRNA -> PutA
Components:
Function Name Type
product PutA protein
reactant putA_mRNA RNA
PutA ubiquinone + proline pyrroline 5-carboxylate + ubiquinol
Name: ubiquinone + proline -> pyrroline 5-carboxylate + ubiquinol
Description: Reaction transforming ubiquinone, proline into pyrroline 5-carboxylate, ubiquinol
Type: state transition
Pathway Components: ubiquinone + proline - PutA -> pyrroline 5-carboxylate + ubiquinol
Components:
Function Name Type
catalyzer PutA protein
reactant proline simple_molecule
product pyrroline 5-carboxylate simple_molecule
product ubiquinol simple_molecule
reactant ubiquinone simple_molecule
PutA glutamate-semialdehyde L-glutamate
Name: glutamate-semialdehyde -> L-glutamate
Description: Reaction transforming glutamate-semialdehyde into L-glutamate
Type: state transition
Pathway Components: glutamate-semialdehyde - PutA -> L-glutamate
Components:
Function Name Type
product L-glutamate simple_molecule
catalyzer PutA protein
reactant glutamate-semialdehyde simple_molecule
fimB_mRNA FimB
Name: fimB_mRNA -> FimB
Description: Translation of FimB
Type: translation
Pathway Components: fimB_mRNA -> FimB
Components:
Function Name Type
product FimB protein
reactant fimB_mRNA RNA
tomB-hha_mRNA TomB
Name: tomB-hha_mRNA -> TomB
Description: Translation of TomB
Type: translation
Pathway Components: tomB-hha_mRNA -> TomB
Components:
Function Name Type
product TomB protein
reactant tomB-hha_mRNA RNA
tomB-hha_mRNA Hha
Name: tomB-hha_mRNA -> Hha
Description: Translation of Hha
Type: translation
Pathway Components: tomB-hha_mRNA -> Hha
Components:
Function Name Type
product Hha protein
reactant tomB-hha_mRNA RNA
cspI_mRNA CspI
Name: cspI_mRNA -> CspI
Description: Translation of CspI
Type: translation
Pathway Components: cspI_mRNA -> CspI
Components:
Function Name Type
product CspI protein
reactant cspI_mRNA RNA
pyrroline 5-carboxylate glutamate-semialdehyde
Name: pyrroline 5-carboxylate -> glutamate-semialdehyde
Description: Transformation of pyrroline 5-carboxylate into glutamate-semialdehyde by one or more reactions not shown.
Type: complementary pathway reaction
Pathway Components: pyrroline 5-carboxylate / SPONTPRO-RXN / glutamate-semialdehyde
Components:
Function Name Type
product glutamate-semialdehyde simple_molecule
reactant pyrroline 5-carboxylate simple_molecule



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