RegulonDB RegulonDB

ArgR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
ketoglutarate ArgA ArgB ArgC ArgD ArgE ArgF ArgG ArgH ArgI ArgR ArgT ArtI ArtJ ArtM ArtP ArtQ AstA AstB AstC AstD AstE CO2 CarA CarB GltB GltD GltF HisJ HisM HisP HisQ InfB L-arginine L-arginine_Ext arginino-succinate asp L-citrulline L-glutamate L-glutamine L-histidine L-histidine_Ext L-lysine L-lysine_Ext This Gensor Unit is not yet available Ornithine Ornithine_Ext NAG 2-acetamido-5-oxopentanoate acetylornithine N-acetylglutamyl-P This Gensor Unit is not yet available N-Succinyl-2-L-amino-6-oxoheptanedioate L,L-SDAP N2-succinylarginine N2-succinylglutamic-semialdehyde N2-succinylornithine N2-Succinyl-L-glutamate NusA Pnp RbfA RimP RpsO TruB a nucleoside 5'-monophosphate NDP ssRNA a tRNA precursor with a 5' extension and a long 3' trailer a tRNA precursor with a 5' extension and a short 3' extension a tRNA pseudouridine55 a tRNA uridine55 acetate ac-CoA ammonium argA argA_mRNA argCBH argCBH_mRNA argD argD_mRNA argE argE_mRNA argF argF_mRNA argG argG_mRNA argI argI_mRNA argR argR_mRNA artJ artJ_mRNA artPIQM artPIQM_mRNA astCADBE astCADBE_mRNA carbonate carAB carAB_mRNA carbamoyl-P CoA PP fumarate gltBDF gltBDF_mRNA hisJQMP hisJQMP_mRNA metY metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA metY_mRNA phosphate succinate suc-coa This Gensor Unit is not yet available ArgR L-arginine ArtP ArtM ArtQ ArtI ArtJ GltB GltD CarB CarA HisP HisM HisQ HisJ HisQ HisP HisM ArgT phosphate phosphate phosphate phosphate L-arginine carbamoyl-P L-glutamate phosphate phosphate phosphate ketoglutarate ketoglutarate ketoglutarate ketoglutarate L-glutamate L-glutamate L-glutamate L-glutamate L-glutamate L-glutamate L-glutamate L-arginine phosphate ammonium CoA ssRNA


Gensor Unit       
Name: ArgR
Description: Molecular biology level
Detailed: In the presence of arginine, ArgR negatively regulates the expression of genes required for the transport of basic amino acids (histidine, lysine and arginine) and ornithine catabolic process, and positively regulates the expression of genes required for catabolism of arginine. Under these conditions, ArgR is modified to ArgR-arginine, binds its target sites preventing its own expression and the expression of some of its regulated genes and enabling the expression of others of its regulated genes.
Less detailed: In the presence of arginine ArgR negatively regulates the expression of genes needed for transport of basic amino acids (histidine, lysine and arginine) and ornithine catabolic process and, positively regulates the expression required for catabolism of arginine.

Physiology level
Detailed: The presence of L-arginine induces the expression of genes related with arginine catabolic process and represses the expression of genes required for catabolism of ornithine. Under these conditions the genes necessary for the conversion of L-arginine to ammonium and CO2 are expressed, and the genes required for conversion of ornithine to L-citruline are not expressed.
Less detailed: The presence of arginine induces the expression of genes needful for catabolism of arginine, and inhibits the expression of genes related with transport of basic amino acids and arginine catabolism.
Classification:
Groups: Transcription
Energy production and conversion
Amino acid transport and metabolism
Translation, ribosomal structure and biogenesis
Gene Ontology Terms (GO): biological_process GO:0044205 - 'de novo' UMP biosynthetic process
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006310 - DNA recombination
GO:0006353 - DNA-templated transcription, termination
GO:0097638 - L-arginine import across plasma membrane
GO:0097054 - L-glutamate biosynthetic process
Read more >
cellular_component GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:0005951 - carbamoyl-phosphate synthase complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0022627 - cytosolic small ribosomal subunit
GO:0016021 - integral component of membrane
Read more >
molecular_function GO:0051538 - 3 iron, 4 sulfur cluster binding
GO:0000175 - 3'-5'-exoribonuclease activity
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0005524 - ATP binding
GO:0016887 - ATPase activity
GO:0015424 - ATPase-coupled amino acid transmembrane transporter activity
GO:0015426 - ATPase-coupled polar amino acid-transporter activity
Read more >
Components:
  Function Name Type
  simple_molecule 2-acetamido-5-oxopentanoate simple_molecule
  protein ArgA protein
  protein ArgB protein
  protein ArgC protein
  protein ArgD protein
  protein ArgE protein
  protein ArgF protein
  protein ArgG protein
  protein ArgH protein
  protein ArgI protein
  protein ArgR protein
  complex ArgR-arginine complex
  protein ArgT protein
  protein ArtI protein
  complex ArtI-ArtM-ArtQ-ArtP complex
  protein ArtJ protein
  complex ArtJ-ArtQ-ArtM-ArtP complex
  protein ArtM protein
  protein ArtP protein
  protein ArtQ protein
  protein AstA protein
  protein AstB protein
  protein AstC protein
  protein AstD protein
  protein AstE protein
  simple_molecule CO2 simple_molecule
  protein CarA protein
  protein CarB protein
  complex CarB-CarA complex
  protein Eno protein
  protein GltB protein
  protein GltD protein
  complex GltD-GltB complex
  protein GltF protein
  protein HisJ protein
  protein HisM protein
  protein HisP protein
  complex HisP-HisM-HisQ-HisJ complex
  protein HisQ protein
  complex HisQ-HisP-HisM-ArgT complex
  protein InfB protein
  simple_molecule L,L-SDAP simple_molecule
  simple_molecule L-glutamate simple_molecule
  protein LysO protein
  simple_molecule N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
  simple_molecule N-acetylglutamyl-P simple_molecule
  simple_molecule N2-Succinyl-L-glutamate simple_molecule
  simple_molecule N2-succinylarginine simple_molecule
  simple_molecule N2-succinylglutamic-semialdehyde simple_molecule
  simple_molecule N2-succinylornithine simple_molecule
  protein NAGS protein
  protein NusA protein
  simple_molecule Ornithine simple_molecule
  simple_molecule Ornithine_Ext simple_molecule
  protein PNPase protein
  protein Pnp protein
  protein Ppk protein
  complex Ppk-Rne-RhlB-Pnp-Eno complex
  protein RNA:L-methionyl-tRNAmetY protein
  protein RNA:N-formyl-L-methionyl-tRNAmetY protein
  protein RbfA protein
  protein RhlB protein
  protein RimP protein
  protein Rne protein
  protein RpsA protein
  complex RpsA-RpsB-RpsC-RpsD-RpsE-RpsF-RpsG-RpsH-RpsI-RpsJ-RpsK-RpsL-RpsM-RpsN-RpsO-RpsP-RpsQ-RpsR-RpsS-RpsT-RpsU-Sra complex
  protein RpsB protein
  protein RpsC protein
  protein RpsD protein
  protein RpsE protein
  protein RpsF protein
  protein RpsG protein
  protein RpsH protein
  protein RpsI protein
  protein RpsJ protein
  protein RpsK protein
  protein RpsL protein
  protein RpsM protein
  protein RpsN protein
  protein RpsO protein
  protein RpsP protein
  protein RpsQ protein
  protein RpsR protein
  protein RpsS protein
  protein RpsT protein
  protein RpsU protein
  protein Sra protein
  protein TruB protein
  simple_molecule acetate simple_molecule
  simple_molecule acetyl-CoA simple_molecule
  simple_molecule acetyl-L-glu simple_molecule
  simple_molecule acetylornithine simple_molecule
  simple_molecule ammonium simple_molecule
  gene argA gene
  RNA argA_mRNA RNA
  gene argCBH gene
  RNA argCBH_mRNA RNA
  gene argD gene
  RNA argD_mRNA RNA
  gene argE gene
  RNA argE_mRNA RNA
  gene argF gene
  RNA argF_mRNA RNA
  gene argG gene
  RNA argG_mRNA RNA
  gene argI gene
  RNA argI_mRNA RNA
  gene argR gene
  RNA argR_mRNA RNA
  simple_molecule arginine simple_molecule
  simple_molecule arginine_Ext simple_molecule
  simple_molecule arginino-succinate simple_molecule
  gene artJ gene
  RNA artJ_mRNA RNA
  gene artPIQM gene
  RNA artPIQM_mRNA RNA
  simple_molecule aspartate simple_molecule
  gene astCADBE gene
  RNA astCADBE_mRNA RNA
  gene carAB gene
  RNA carAB_mRNA RNA
  simple_molecule carbamoyl-P simple_molecule
  simple_molecule carbonate simple_molecule
  simple_molecule citrulline simple_molecule
  simple_molecule coenzyme A simple_molecule
  simple_molecule diphosphate simple_molecule
  simple_molecule fumarate simple_molecule
  gene gltBDF gene
  RNA gltBDF_mRNA RNA
  simple_molecule glutamine simple_molecule
  gene hisJQMP gene
  RNA hisJQMP_mRNA RNA
  simple_molecule histidine simple_molecule
  simple_molecule histidine_Ext simple_molecule
  simple_molecule ketoglutarate simple_molecule
  gene lysO gene
  RNA lysO_mRNA RNA
  simple_molecule lysine simple_molecule
  simple_molecule lysine_Ext simple_molecule
  gene metY gene
  gene metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp gene
  RNA metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA RNA
  protein metY-tRNA protein
  RNA metY_mRNA RNA
  simple_molecule mononucleotide simple_molecule
  simple_molecule nucleoside diphosphate simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule single-stranded RNA simple_molecule
  simple_molecule suc-coa simple_molecule
  simple_molecule succinate simple_molecule
  simple_molecule tRNA precursor with a 5' extension and a long 3' trailer simple_molecule
  simple_molecule tRNA precursor with a 5' extension and a short 3' extension simple_molecule
  simple_molecule tRNA pseudouridine55 simple_molecule
  simple_molecule tRNA uridine55 simple_molecule


Reactions       
Showing 95 reactions
arginine + ArgR ArgR-arginine
Name: arginine + ArgR -> ArgR-arginine
Description: Reaction transforming arginine, ArgR into ArgR-arginine
Type: state transition
Pathway Components: arginine + ArgR -> ArgR-arginine
Components:
Function Name Type
reactant ArgR protein
product ArgR-arginine complex
reactant arginine simple_molecule
ArgR-arginine astCADBE astCADBE_mRNA
Name: astCADBE -> astCADBE_mRNA
Description: Transcription of transcription unit astCADBE. Reaction activation by ArgR-arginine.
Type: transcription
Pathway Components: astCADBE - ArgR-arginine -> astCADBE_mRNA
Components:
Function Name Type
activator ArgR-arginine complex
reactant astCADBE gene
product astCADBE_mRNA RNA
ArgR-arginine argA argA_mRNA
Name: argA -> argA_mRNA
Description: Transcription of transcription unit argA. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argA - ArgR-arginine -> argA_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argA gene
product argA_mRNA RNA
ArgR-arginine argCBH argCBH_mRNA
Name: argCBH -> argCBH_mRNA
Description: Transcription of transcription unit argCBH. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argCBH - ArgR-arginine -> argCBH_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argCBH gene
product argCBH_mRNA RNA
ArgR-arginine argD argD_mRNA
Name: argD -> argD_mRNA
Description: Transcription of transcription unit argD. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argD - ArgR-arginine -> argD_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argD gene
product argD_mRNA RNA
ArgR-arginine argE argE_mRNA
Name: argE -> argE_mRNA
Description: Transcription of transcription unit argE. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argE - ArgR-arginine -> argE_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argE gene
product argE_mRNA RNA
ArgR-arginine argF argF_mRNA
Name: argF -> argF_mRNA
Description: Transcription of transcription unit argF. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argF - ArgR-arginine -> argF_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argF gene
product argF_mRNA RNA
ArgR-arginine argG argG_mRNA
Name: argG -> argG_mRNA
Description: Transcription of transcription unit argG. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argG - ArgR-arginine -> argG_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argG gene
product argG_mRNA RNA
ArgR-arginine argI argI_mRNA
Name: argI -> argI_mRNA
Description: Transcription of transcription unit argI. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argI - ArgR-arginine -> argI_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argI gene
product argI_mRNA RNA
ArgR-arginine argR argR_mRNA
Name: argR -> argR_mRNA
Description: Transcription of transcription unit argR. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: argR - ArgR-arginine -> argR_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant argR gene
product argR_mRNA RNA
ArgR-arginine artJ artJ_mRNA
Name: artJ -> artJ_mRNA
Description: Transcription of transcription unit artJ. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: artJ - ArgR-arginine -> artJ_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant artJ gene
product artJ_mRNA RNA
ArgR-arginine artPIQM artPIQM_mRNA
Name: artPIQM -> artPIQM_mRNA
Description: Transcription of transcription unit artPIQM. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: artPIQM - ArgR-arginine -> artPIQM_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant artPIQM gene
product artPIQM_mRNA RNA
ArgR-arginine carAB carAB_mRNA
Name: carAB -> carAB_mRNA
Description: Transcription of transcription unit carAB. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: carAB - ArgR-arginine -> carAB_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant carAB gene
product carAB_mRNA RNA
ArgR-arginine gltBDF gltBDF_mRNA
Name: gltBDF -> gltBDF_mRNA
Description: Transcription of transcription unit gltBDF. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: gltBDF - ArgR-arginine -> gltBDF_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant gltBDF gene
product gltBDF_mRNA RNA
ArgR-arginine hisJQMP hisJQMP_mRNA
Name: hisJQMP -> hisJQMP_mRNA
Description: Transcription of transcription unit hisJQMP. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: hisJQMP - ArgR-arginine -> hisJQMP_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant hisJQMP gene
product hisJQMP_mRNA RNA
ArgR-arginine lysO lysO_mRNA
Name: lysO -> lysO_mRNA
Description: Transcription of transcription unit lysO. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: lysO - ArgR-arginine -> lysO_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant lysO gene
product lysO_mRNA RNA
ArgR-arginine metY metY_mRNA
Name: metY -> metY_mRNA
Description: Transcription of transcription unit metY. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: metY - ArgR-arginine -> metY_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant metY gene
product metY_mRNA RNA
ArgR-arginine metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA
Name: metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp -> metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA
Description: Transcription of transcription unit metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp. Reaction inhibition by ArgR-arginine.
Type: transcription
Pathway Components: metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp - ArgR-arginine -> metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA
Components:
Function Name Type
inhibitor ArgR-arginine complex
reactant metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp gene
product metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp_mRNA RNA
artJ_mRNA ArtJ
Name: artJ_mRNA -> ArtJ
Description: Translation of ArtJ
Type: translation
Pathway Components: artJ_mRNA -> ArtJ
Components:
Function Name Type
product ArtJ protein
reactant artJ_mRNA RNA
ArtP + ArtJ + ArtM + ArtQ ArtJ-ArtQ-ArtM-ArtP
Name: ArtP + ArtJ + ArtM + ArtQ -> ArtJ-ArtQ-ArtM-ArtP
Description: Reaction transforming ArtP, ArtJ, ArtM, ArtQ into ArtJ-ArtQ-ArtM-ArtP
Type: state transition
Pathway Components: ArtP + ArtJ + ArtM + ArtQ -> ArtJ-ArtQ-ArtM-ArtP
Components:
Function Name Type
reactant ArtJ protein
product ArtJ-ArtQ-ArtM-ArtP complex
reactant ArtM protein
reactant ArtP protein
reactant ArtQ protein
ArtJ-ArtQ-ArtM-ArtP HisQ-HisP-HisM-ArgT arginine_Ext arginine
Name: arginine_Ext -> arginine
Description: Transport of arginine_Ext through a bacterial membrane, leading to the presence of arginine inside the cell.
Type: transport
Pathway Components: arginine_Ext - ArtJ-ArtQ-ArtM-ArtP - HisQ-HisP-HisM-ArgT -> arginine
Components:
Function Name Type
catalyzer ArtJ-ArtQ-ArtM-ArtP complex
catalyzer HisQ-HisP-HisM-ArgT complex
product arginine simple_molecule
reactant arginine_Ext simple_molecule
gltBDF_mRNA GltB
Name: gltBDF_mRNA -> GltB
Description: Translation of GltB
Type: translation
Pathway Components: gltBDF_mRNA -> GltB
Components:
Function Name Type
product GltB protein
reactant gltBDF_mRNA RNA
GltB + GltD GltD-GltB
Name: GltB + GltD -> GltD-GltB
Description: Reaction transforming GltB, GltD into GltD-GltB
Type: state transition
Pathway Components: GltB + GltD -> GltD-GltB
Components:
Function Name Type
reactant GltB protein
reactant GltD protein
product GltD-GltB complex
gltBDF_mRNA GltD
Name: gltBDF_mRNA -> GltD
Description: Translation of GltD
Type: translation
Pathway Components: gltBDF_mRNA -> GltD
Components:
Function Name Type
product GltD protein
reactant gltBDF_mRNA RNA
gltBDF_mRNA GltF
Name: gltBDF_mRNA -> GltF
Description: Translation of GltF
Type: translation
Pathway Components: gltBDF_mRNA -> GltF
Components:
Function Name Type
product GltF protein
reactant gltBDF_mRNA RNA
argD_mRNA ArgD
Name: argD_mRNA -> ArgD
Description: Translation of ArgD
Type: translation
Pathway Components: argD_mRNA -> ArgD
Components:
Function Name Type
product ArgD protein
reactant argD_mRNA RNA
ArgD AstC 2-acetamido-5-oxopentanoate + L-glutamate acetylornithine + ketoglutarate
Name: 2-acetamido-5-oxopentanoate + L-glutamate -> acetylornithine + ketoglutarate
Description: Reaction transforming 2-acetamido-5-oxopentanoate, L-glutamate into acetylornithine, ketoglutarate
Type: state transition
Pathway Components: 2-acetamido-5-oxopentanoate + L-glutamate - ArgD - AstC -> acetylornithine + ketoglutarate
Components:
Function Name Type
reactant 2-acetamido-5-oxopentanoate simple_molecule
catalyzer ArgD protein
catalyzer AstC protein
reactant L-glutamate simple_molecule
product acetylornithine simple_molecule
product ketoglutarate simple_molecule
ArgD ketoglutarate ketoglutarate + L,L-SDAP Products
Name: ketoglutarate + L,L-SDAP -> N-Succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate
Description: Reaction transforming ketoglutarate, L,L-SDAP into N-Succinyl-2-L-amino-6-oxoheptanedioate, L-glutamate
Type: state transition
Pathway Components: ketoglutarate + L,L-SDAP - ArgD - ketoglutarate -> N-Succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate
Components:
Function Name Type
catalyzer ArgD protein
reactant L,L-SDAP simple_molecule
product L-glutamate simple_molecule
product N-Succinyl-2-L-amino-6-oxoheptanedioate simple_molecule
inhibitor ketoglutarate simple_molecule
reactant ketoglutarate simple_molecule
argI_mRNA ArgI
Name: argI_mRNA -> ArgI
Description: Translation of ArgI
Type: translation
Pathway Components: argI_mRNA -> ArgI
Components:
Function Name Type
product ArgI protein
reactant argI_mRNA RNA
ArgF ArgI carbamoyl-P + Ornithine citrulline + phosphate
Name: carbamoyl-P + Ornithine -> citrulline + phosphate
Description: Reaction transforming carbamoyl-P, Ornithine into citrulline, phosphate
Type: state transition
Pathway Components: carbamoyl-P + Ornithine - ArgF - ArgI -> citrulline + phosphate
Components:
Function Name Type
catalyzer ArgF protein
catalyzer ArgI protein
reactant Ornithine simple_molecule
reactant carbamoyl-P simple_molecule
product citrulline simple_molecule
product phosphate simple_molecule
astCADBE_mRNA AstC
Name: astCADBE_mRNA -> AstC
Description: Translation of AstC
Type: translation
Pathway Components: astCADBE_mRNA -> AstC
Components:
Function Name Type
product AstC protein
reactant astCADBE_mRNA RNA
AstC N2-succinylornithine + ketoglutarate N2-succinylglutamic-semialdehyde + L-glutamate
Name: N2-succinylornithine + ketoglutarate -> N2-succinylglutamic-semialdehyde + L-glutamate
Description: Reaction transforming N2-succinylornithine, ketoglutarate into N2-succinylglutamic-semialdehyde, L-glutamate
Type: state transition
Pathway Components: N2-succinylornithine + ketoglutarate - AstC -> N2-succinylglutamic-semialdehyde + L-glutamate
Components:
Function Name Type
catalyzer AstC protein
product L-glutamate simple_molecule
product N2-succinylglutamic-semialdehyde simple_molecule
reactant N2-succinylornithine simple_molecule
reactant ketoglutarate simple_molecule
astCADBE_mRNA AstA
Name: astCADBE_mRNA -> AstA
Description: Translation of AstA
Type: translation
Pathway Components: astCADBE_mRNA -> AstA
Components:
Function Name Type
product AstA protein
reactant astCADBE_mRNA RNA
AstA arginine + suc-coa N2-succinylarginine + coenzyme A
Name: arginine + suc-coa -> N2-succinylarginine + coenzyme A
Description: Reaction transforming arginine, suc-coa into N2-succinylarginine, coenzyme A
Type: state transition
Pathway Components: arginine + suc-coa - AstA -> N2-succinylarginine + coenzyme A
Components:
Function Name Type
catalyzer AstA protein
product N2-succinylarginine simple_molecule
reactant arginine simple_molecule
product coenzyme A simple_molecule
reactant suc-coa simple_molecule
astCADBE_mRNA AstD
Name: astCADBE_mRNA -> AstD
Description: Translation of AstD
Type: translation
Pathway Components: astCADBE_mRNA -> AstD
Components:
Function Name Type
product AstD protein
reactant astCADBE_mRNA RNA
AstD N2-succinylglutamic-semialdehyde N2-Succinyl-L-glutamate
Name: N2-succinylglutamic-semialdehyde -> N2-Succinyl-L-glutamate
Description: Reaction transforming N2-succinylglutamic-semialdehyde into N2-Succinyl-L-glutamate
Type: state transition
Pathway Components: N2-succinylglutamic-semialdehyde - AstD -> N2-Succinyl-L-glutamate
Components:
Function Name Type
catalyzer AstD protein
product N2-Succinyl-L-glutamate simple_molecule
reactant N2-succinylglutamic-semialdehyde simple_molecule
astCADBE_mRNA AstB
Name: astCADBE_mRNA -> AstB
Description: Translation of AstB
Type: translation
Pathway Components: astCADBE_mRNA -> AstB
Components:
Function Name Type
product AstB protein
reactant astCADBE_mRNA RNA
AstB N2-succinylarginine N2-succinylornithine + ammonium + CO2
Name: N2-succinylarginine -> N2-succinylornithine + ammonium + CO2
Description: Reaction transforming N2-succinylarginine into N2-succinylornithine, ammonium , CO2
Type: state transition
Pathway Components: N2-succinylarginine - AstB -> N2-succinylornithine + ammonium + CO2
Components:
Function Name Type
catalyzer AstB protein
product CO2 simple_molecule
reactant N2-succinylarginine simple_molecule
product N2-succinylornithine simple_molecule
product ammonium simple_molecule
astCADBE_mRNA AstE
Name: astCADBE_mRNA -> AstE
Description: Translation of AstE
Type: translation
Pathway Components: astCADBE_mRNA -> AstE
Components:
Function Name Type
product AstE protein
reactant astCADBE_mRNA RNA
AstE N2-Succinyl-L-glutamate L-glutamate + succinate
Name: N2-Succinyl-L-glutamate -> L-glutamate + succinate
Description: Reaction transforming N2-Succinyl-L-glutamate into L-glutamate, succinate
Type: state transition
Pathway Components: N2-Succinyl-L-glutamate - AstE -> L-glutamate + succinate
Components:
Function Name Type
catalyzer AstE protein
product L-glutamate simple_molecule
reactant N2-Succinyl-L-glutamate simple_molecule
product succinate simple_molecule
argA_mRNA ArgA
Name: argA_mRNA -> ArgA
Description: Translation of ArgA
Type: translation
Pathway Components: argA_mRNA -> ArgA
Components:
Function Name Type
product ArgA protein
reactant argA_mRNA RNA
ArgA NAGS arginine citrulline L-glutamate + acetyl-CoA acetyl-L-glu + coenzyme A
Name: L-glutamate + acetyl-CoA -> acetyl-L-glu + coenzyme A
Description: Reaction transforming L-glutamate, acetyl-CoA into acetyl-L-glu, coenzyme A
Type: state transition
Pathway Components: L-glutamate + acetyl-CoA - ArgA - NAGS - arginine - citrulline -> acetyl-L-glu + coenzyme A
Components:
Function Name Type
catalyzer ArgA protein
reactant L-glutamate simple_molecule
catalyzer NAGS protein
reactant acetyl-CoA simple_molecule
product acetyl-L-glu simple_molecule
inhibitor arginine simple_molecule
inhibitor citrulline simple_molecule
product coenzyme A simple_molecule
argA_mRNA NAGS
Name: argA_mRNA -> NAGS
Description: Translation of NAGS
Type: translation
Pathway Components: argA_mRNA -> NAGS
Components:
Function Name Type
product NAGS protein
reactant argA_mRNA RNA
carAB_mRNA CarA
Name: carAB_mRNA -> CarA
Description: Translation of CarA
Type: translation
Pathway Components: carAB_mRNA -> CarA
Components:
Function Name Type
product CarA protein
reactant carAB_mRNA RNA
CarA + CarB CarB-CarA
Name: CarA + CarB -> CarB-CarA
Description: Reaction transforming CarA, CarB into CarB-CarA
Type: state transition
Pathway Components: CarA + CarB -> CarB-CarA
Components:
Function Name Type
reactant CarA protein
reactant CarB protein
product CarB-CarA complex
CarB-CarA Ornithine ammonium carbonate + glutamine carbamoyl-P + L-glutamate + phosphate
Name: carbonate + glutamine -> carbamoyl-P + L-glutamate + phosphate
Description: Reaction transforming carbonate, glutamine into carbamoyl-P, L-glutamate , phosphate
Type: state transition
Pathway Components: carbonate + glutamine - CarB-CarA - Ornithine - ammonium -> carbamoyl-P + L-glutamate + phosphate
Components:
Function Name Type
catalyzer CarB-CarA complex
product L-glutamate simple_molecule
inhibitor Ornithine simple_molecule
inhibitor ammonium simple_molecule
product carbamoyl-P simple_molecule
reactant carbonate simple_molecule
reactant glutamine simple_molecule
product phosphate simple_molecule
CarB-CarA glutamine L-glutamate + ammonium
Name: glutamine -> L-glutamate + ammonium
Description: Reaction transforming glutamine into L-glutamate, ammonium
Type: state transition
Pathway Components: glutamine - CarB-CarA -> L-glutamate + ammonium
Components:
Function Name Type
catalyzer CarB-CarA complex
product L-glutamate simple_molecule
product ammonium simple_molecule
reactant glutamine simple_molecule
CarB-CarA carbonate + ammonium carbamoyl-P + phosphate
Name: carbonate + ammonium -> carbamoyl-P + phosphate
Description: Reaction transforming carbonate, ammonium into carbamoyl-P, phosphate
Type: state transition
Pathway Components: carbonate + ammonium - CarB-CarA -> carbamoyl-P + phosphate
Components:
Function Name Type
catalyzer CarB-CarA complex
reactant ammonium simple_molecule
product carbamoyl-P simple_molecule
reactant carbonate simple_molecule
product phosphate simple_molecule
carAB_mRNA CarB
Name: carAB_mRNA -> CarB
Description: Translation of CarB
Type: translation
Pathway Components: carAB_mRNA -> CarB
Components:
Function Name Type
product CarB protein
reactant carAB_mRNA RNA
metY_mRNA metY-tRNA
Name: metY_mRNA -> metY-tRNA
Description: Translation of metY-tRNA
Type: translation
Pathway Components: metY_mRNA -> metY-tRNA
Components:
Function Name Type
product metY-tRNA protein
reactant metY_mRNA RNA
metY_mRNA RNA:L-methionyl-tRNAmetY
Name: metY_mRNA -> RNA:L-methionyl-tRNAmetY
Description: Translation of RNA:L-methionyl-tRNAmetY
Type: translation
Pathway Components: metY_mRNA -> RNA:L-methionyl-tRNAmetY
Components:
Function Name Type
product RNA:L-methionyl-tRNAmetY protein
reactant metY_mRNA RNA
metY_mRNA RNA:N-formyl-L-methionyl-tRNAmetY
Name: metY_mRNA -> RNA:N-formyl-L-methionyl-tRNAmetY
Description: Translation of RNA:N-formyl-L-methionyl-tRNAmetY
Type: translation
Pathway Components: metY_mRNA -> RNA:N-formyl-L-methionyl-tRNAmetY
Components:
Function Name Type
product RNA:N-formyl-L-methionyl-tRNAmetY protein
reactant metY_mRNA RNA
hisJQMP_mRNA HisJ
Name: hisJQMP_mRNA -> HisJ
Description: Translation of HisJ
Type: translation
Pathway Components: hisJQMP_mRNA -> HisJ
Components:
Function Name Type
product HisJ protein
reactant hisJQMP_mRNA RNA
HisJ + HisQ + HisP + HisM HisP-HisM-HisQ-HisJ
Name: HisJ + HisQ + HisP + HisM -> HisP-HisM-HisQ-HisJ
Description: Reaction transforming HisJ, HisQ, HisP, HisM into HisP-HisM-HisQ-HisJ
Type: state transition
Pathway Components: HisJ + HisQ + HisP + HisM -> HisP-HisM-HisQ-HisJ
Components:
Function Name Type
reactant HisJ protein
reactant HisM protein
reactant HisP protein
product HisP-HisM-HisQ-HisJ complex
reactant HisQ