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AcrR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
TolC caprate_Ext AcrA rhodamine 6G RNA:MicF AcrR SoxS acrAB ethidium ethidium caprate acriflavine_Ext drug_Ext proflavin acrR_mRNA micF AcrA FlhD MarR micF_mRNA FlhC acriflavine rhodamine 6G chenodiol_Ext flhDC FlhD soxS soxR_mRNA hexane_Ext AcrD AcrA hexane drug TolC soxR AcrR enterobactin_Ext AcrB chenodiol AcrD soxS_mRNA enterobactin proflavin TolC marRAB AcrB FlhC AcrR flhDC_mRNA SoxR MarB AcrR marRAB_mRNA MarA acrAB_mRNA acrR


Gensor Unit       
Name: AcrR
Classification:
Groups: Transcription
Defense mechanisms
Cell wall/membrane/envelope biogenesis
Gene Ontology Terms (GO): biological_process GO:0015895 - alkane transport
GO:0044780 - bacterial-type flagellum assembly
GO:0044781 - bacterial-type flagellum organization
GO:0015721 - bile acid and bile salt transport
GO:0071474 - cellular hyperosmotic response
GO:0071236 - cellular response to antibiotic
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cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:1990281 - efflux pump complex
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0031237 - intrinsic component of periplasmic side of plasma membrane
GO:0031226 - intrinsic component of plasma membrane
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molecular_function GO:0051537 - 2 iron, 2 sulfur cluster binding
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0015567 - alkane transmembrane transporter activity
GO:0000985 - bacterial-type RNA polymerase core promoter sequence-specific DNA binding
GO:0001108 - bacterial-type RNA polymerase holo enzyme binding
Read more >
Components:
  Function Name Type
  protein AcrA protein
  complex AcrA-TolC-AcrB complex
  protein AcrB protein
  protein AcrD protein
  complex AcrD-AcrA-TolC complex
  protein AcrR protein
  complex AcrR-ethidium complex
  complex AcrR-proflavin complex
  complex AcrR-rhodamine 6G complex
  protein FlhC protein
  protein FlhD protein
  complex FlhD-FlhC complex
  protein MarA protein
  protein MarB protein
  protein MarR protein
  protein RNA:MicF protein
  protein SoxR protein
  protein SoxS protein
  protein TolC protein
  gene acrAB gene
  RNA acrAB_mRNA RNA
  gene acrR gene
  RNA acrR_mRNA RNA
  simple_molecule acriflavine simple_molecule
  simple_molecule acriflavine_Ext simple_molecule
  simple_molecule caprate simple_molecule
  simple_molecule caprate_Ext simple_molecule
  simple_molecule chenodiol simple_molecule
  simple_molecule chenodiol_Ext simple_molecule
  simple_molecule drug simple_molecule
  simple_molecule drug_Ext simple_molecule
  simple_molecule enterobactin simple_molecule
  simple_molecule enterobactin_Ext simple_molecule
  simple_molecule ethidium simple_molecule
  gene flhDC gene
  RNA flhDC_mRNA RNA
  simple_molecule hexane simple_molecule
  simple_molecule hexane_Ext simple_molecule
  gene marRAB gene
  RNA marRAB_mRNA RNA
  gene micF gene
  RNA micF_mRNA RNA
  simple_molecule proflavin simple_molecule
  simple_molecule rhodamine 6G simple_molecule
  gene soxR gene
  RNA soxR_mRNA RNA
  gene soxS gene
  RNA soxS_mRNA RNA


Reactions       
Showing 30 reactions
AcrR acrAB acrAB_mRNA
Name: acrAB -> acrAB_mRNA
Description: Transcription of transcription unit acrAB. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: acrAB - AcrR -> acrAB_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant acrAB gene
product acrAB_mRNA RNA
AcrR acrR acrR_mRNA
Name: acrR -> acrR_mRNA
Description: Transcription of transcription unit acrR. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: acrR - AcrR -> acrR_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant acrR gene
product acrR_mRNA RNA
AcrR flhDC flhDC_mRNA
Name: flhDC -> flhDC_mRNA
Description: Transcription of transcription unit flhDC. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: flhDC - AcrR -> flhDC_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant flhDC gene
product flhDC_mRNA RNA
AcrR marRAB marRAB_mRNA
Name: marRAB -> marRAB_mRNA
Description: Transcription of transcription unit marRAB. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: marRAB - AcrR -> marRAB_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant marRAB gene
product marRAB_mRNA RNA
AcrR micF micF_mRNA
Name: micF -> micF_mRNA
Description: Transcription of transcription unit micF. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: micF - AcrR -> micF_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant micF gene
product micF_mRNA RNA
AcrR soxR soxR_mRNA
Name: soxR -> soxR_mRNA
Description: Transcription of transcription unit soxR. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: soxR - AcrR -> soxR_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant soxR gene
product soxR_mRNA RNA
AcrR soxS soxS_mRNA
Name: soxS -> soxS_mRNA
Description: Transcription of transcription unit soxS. Reaction inhibition by AcrR.
Type: transcription
Pathway Components: soxS - AcrR -> soxS_mRNA
Components:
Function Name Type
inhibitor AcrR protein
reactant soxS gene
product soxS_mRNA RNA
proflavin + AcrR AcrR-proflavin
Name: proflavin + AcrR -> AcrR-proflavin
Description: Reaction transforming proflavin, AcrR into AcrR-proflavin
Type: state transition
Pathway Components: proflavin + AcrR -> AcrR-proflavin
Components:
Function Name Type
reactant AcrR protein
product AcrR-proflavin complex
reactant proflavin simple_molecule
rhodamine 6G + AcrR AcrR-rhodamine 6G
Name: rhodamine 6G + AcrR -> AcrR-rhodamine 6G
Description: Reaction transforming rhodamine 6G, AcrR into AcrR-rhodamine 6G
Type: state transition
Pathway Components: rhodamine 6G + AcrR -> AcrR-rhodamine 6G
Components:
Function Name Type
reactant AcrR protein
product AcrR-rhodamine 6G complex
reactant rhodamine 6G simple_molecule
ethidium + AcrR AcrR-ethidium
Name: ethidium + AcrR -> AcrR-ethidium
Description: Reaction transforming ethidium, AcrR into AcrR-ethidium
Type: state transition
Pathway Components: ethidium + AcrR -> AcrR-ethidium
Components:
Function Name Type
reactant AcrR protein
product AcrR-ethidium complex
reactant ethidium simple_molecule
soxS_mRNA SoxS
Name: soxS_mRNA -> SoxS
Description: Translation of SoxS
Type: translation
Pathway Components: soxS_mRNA -> SoxS
Components:
Function Name Type
product SoxS protein
reactant soxS_mRNA RNA
soxR_mRNA SoxR
Name: soxR_mRNA -> SoxR
Description: Translation of SoxR
Type: translation
Pathway Components: soxR_mRNA -> SoxR
Components:
Function Name Type
product SoxR protein
reactant soxR_mRNA RNA
acrAB_mRNA AcrA
Name: acrAB_mRNA -> AcrA
Description: Translation of AcrA
Type: translation
Pathway Components: acrAB_mRNA -> AcrA
Components:
Function Name Type
product AcrA protein
reactant acrAB_mRNA RNA
TolC + AcrA + AcrD AcrD-AcrA-TolC
Name: TolC + AcrA + AcrD -> AcrD-AcrA-TolC
Description: Reaction transforming TolC, AcrA, AcrD into AcrD-AcrA-TolC
Type: state transition
Pathway Components: TolC + AcrA + AcrD -> AcrD-AcrA-TolC
Components:
Function Name Type
reactant AcrA protein
reactant AcrD protein
product AcrD-AcrA-TolC complex
reactant TolC protein
AcrA-TolC-AcrB AcrD-AcrA-TolC drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - AcrA-TolC-AcrB - AcrD-AcrA-TolC -> drug
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
catalyzer AcrD-AcrA-TolC complex
product drug simple_molecule
reactant drug_Ext simple_molecule
AcrB + TolC + AcrA AcrA-TolC-AcrB
Name: AcrB + TolC + AcrA -> AcrA-TolC-AcrB
Description: Reaction transforming AcrB, TolC, AcrA into AcrA-TolC-AcrB
Type: state transition
Pathway Components: AcrB + TolC + AcrA -> AcrA-TolC-AcrB
Components:
Function Name Type
reactant AcrA protein
product AcrA-TolC-AcrB complex
reactant AcrB protein
reactant TolC protein
AcrA-TolC-AcrB acriflavine_Ext acriflavine
Name: acriflavine_Ext -> acriflavine
Description: Transport of acriflavine_Ext through a bacterial membrane, leading to the presence of acriflavine inside the cell.
Type: transport
Pathway Components: acriflavine_Ext - AcrA-TolC-AcrB -> acriflavine
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
product acriflavine simple_molecule
reactant acriflavine_Ext simple_molecule
AcrA-TolC-AcrB chenodiol_Ext chenodiol
Name: chenodiol_Ext -> chenodiol
Description: Transport of chenodiol_Ext through a bacterial membrane, leading to the presence of chenodiol inside the cell.
Type: transport
Pathway Components: chenodiol_Ext - AcrA-TolC-AcrB -> chenodiol
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
product chenodiol simple_molecule
reactant chenodiol_Ext simple_molecule
AcrA-TolC-AcrB caprate_Ext caprate
Name: caprate_Ext -> caprate
Description: Transport of caprate_Ext through a bacterial membrane, leading to the presence of caprate inside the cell.
Type: transport
Pathway Components: caprate_Ext - AcrA-TolC-AcrB -> caprate
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
product caprate simple_molecule
reactant caprate_Ext simple_molecule
AcrA-TolC-AcrB hexane_Ext hexane
Name: hexane_Ext -> hexane
Description: Transport of hexane_Ext through a bacterial membrane, leading to the presence of hexane inside the cell.
Type: transport
Pathway Components: hexane_Ext - AcrA-TolC-AcrB -> hexane
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
product hexane simple_molecule
reactant hexane_Ext simple_molecule
AcrA-TolC-AcrB enterobactin_Ext enterobactin
Name: enterobactin_Ext -> enterobactin
Description: Transport of enterobactin_Ext through a bacterial membrane, leading to the presence of enterobactin inside the cell.
Type: transport
Pathway Components: enterobactin_Ext - AcrA-TolC-AcrB -> enterobactin
Components:
Function Name Type
catalyzer AcrA-TolC-AcrB complex
product enterobactin simple_molecule
reactant enterobactin_Ext simple_molecule
acrAB_mRNA AcrB
Name: acrAB_mRNA -> AcrB
Description: Translation of AcrB
Type: translation
Pathway Components: acrAB_mRNA -> AcrB
Components:
Function Name Type
product AcrB protein
reactant acrAB_mRNA RNA
acrR_mRNA AcrR
Name: acrR_mRNA -> AcrR
Description: Translation of AcrR
Type: translation
Pathway Components: acrR_mRNA -> AcrR
Components:
Function Name Type
product AcrR protein
reactant acrR_mRNA RNA
marRAB_mRNA MarR
Name: marRAB_mRNA -> MarR
Description: Translation of MarR
Type: translation
Pathway Components: marRAB_mRNA -> MarR
Components:
Function Name Type
product MarR protein
reactant marRAB_mRNA RNA
marRAB_mRNA MarA
Name: marRAB_mRNA -> MarA
Description: Translation of MarA
Type: translation
Pathway Components: marRAB_mRNA -> MarA
Components:
Function Name Type
product MarA protein
reactant marRAB_mRNA RNA
marRAB_mRNA MarB
Name: marRAB_mRNA -> MarB
Description: Translation of MarB
Type: translation
Pathway Components: marRAB_mRNA -> MarB
Components:
Function Name Type
product MarB protein
reactant marRAB_mRNA RNA
flhDC_mRNA FlhD
Name: flhDC_mRNA -> FlhD
Description: Translation of FlhD
Type: translation
Pathway Components: flhDC_mRNA -> FlhD
Components:
Function Name Type
product FlhD protein
reactant flhDC_mRNA RNA
FlhC + FlhD FlhD-FlhC
Name: FlhC + FlhD -> FlhD-FlhC
Description: Reaction transforming FlhC, FlhD into FlhD-FlhC
Type: state transition
Pathway Components: FlhC + FlhD -> FlhD-FlhC
Components:
Function Name Type
reactant FlhC protein
reactant FlhD protein
product FlhD-FlhC complex
flhDC_mRNA FlhC
Name: flhDC_mRNA -> FlhC
Description: Translation of FlhC
Type: translation
Pathway Components: flhDC_mRNA -> FlhC
Components:
Function Name Type
product FlhC protein
reactant flhDC_mRNA RNA
micF_mRNA RNA:MicF
Name: micF_mRNA -> RNA:MicF
Description: Translation of RNA:MicF
Type: translation
Pathway Components: micF_mRNA -> RNA:MicF
Components:
Function Name Type
product RNA:MicF protein
reactant micF_mRNA RNA



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