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NimR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
azomycin_Ext drug_Ext nimR nimT_mRNA nimR_mRNA drug azomycin NimR nimT NimT


Gensor Unit       
Name: NimR
Classification:
Groups: Function unknown
Gene Ontology Terms (GO): biological_process GO:0019249 - lactate biosynthetic process
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0045892 - negative regulation of transcription, DNA-templated
GO:0006355 - regulation of transcription, DNA-templated
GO:0046677 - response to antibiotic
GO:0006351 - transcription, DNA-templated
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cellular_component GO:0005829 - cytosol
GO:0016021 - integral component of membrane
GO:0005887 - integral component of plasma membrane
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0019172 - glyoxalase III activity
GO:0043565 - sequence-specific DNA binding
GO:0022857 - transmembrane transporter activity
Components:
  Function Name Type
  protein NimR protein
  protein NimT protein
  simple_molecule azomycin simple_molecule
  simple_molecule azomycin_Ext simple_molecule
  simple_molecule drug simple_molecule
  simple_molecule drug_Ext simple_molecule
  gene nimR gene
  RNA nimR_mRNA RNA
  gene nimT gene
  RNA nimT_mRNA RNA


Reactions       
Showing 6 reactions
NimR nimR nimR_mRNA
Name: nimR -> nimR_mRNA
Description: Transcription of transcription unit nimR. Reaction inhibition by NimR.
Type: transcription
Pathway Components: nimR - NimR -> nimR_mRNA
Components:
Function Name Type
inhibitor NimR protein
reactant nimR gene
product nimR_mRNA RNA
NimR nimT nimT_mRNA
Name: nimT -> nimT_mRNA
Description: Transcription of transcription unit nimT. Reaction inhibition by NimR.
Type: transcription
Pathway Components: nimT - NimR -> nimT_mRNA
Components:
Function Name Type
inhibitor NimR protein
reactant nimT gene
product nimT_mRNA RNA
nimR_mRNA NimR
Name: nimR_mRNA -> NimR
Description: Translation of NimR
Type: translation
Pathway Components: nimR_mRNA -> NimR
Components:
Function Name Type
product NimR protein
reactant nimR_mRNA RNA
nimT_mRNA NimT
Name: nimT_mRNA -> NimT
Description: Translation of NimT
Type: translation
Pathway Components: nimT_mRNA -> NimT
Components:
Function Name Type
product NimT protein
reactant nimT_mRNA RNA
NimT drug_Ext drug
Name: drug_Ext -> drug
Description: Transport of drug_Ext through a bacterial membrane, leading to the presence of drug inside the cell.
Type: transport
Pathway Components: drug_Ext - NimT -> drug
Components:
Function Name Type
catalyzer NimT protein
product drug simple_molecule
reactant drug_Ext simple_molecule
NimT azomycin_Ext azomycin
Name: azomycin_Ext -> azomycin
Description: Transport of azomycin_Ext through a bacterial membrane, leading to the presence of azomycin inside the cell.
Type: transport
Pathway Components: azomycin_Ext - NimT -> azomycin
Components:
Function Name Type
catalyzer NimT protein
product azomycin simple_molecule
reactant azomycin_Ext simple_molecule



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