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| Operon |  |
|---|---|
| Name: | cspE |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | cspE |
| Gene(s): | cspE Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | The mRNA produced by the cspE gene has been observed mainly in the poles of the cell Kannaiah S, Livny J, Amster-Choder O,2019. |
| Evidence: | [LTED] Length of transcript experimentally determined |
| Reference(s): | [1] Uppal S., et al., 2008 |
| Promoter | |
| Name: | cspEp1 |
| +1: | 657147 |
| Sigma Factor: | Sigma70 Sigmulon |
| Distance from start of the gene: | 145 |
| Sequence: |
gtactttgcctggatgcgctttcagttttgagacaaatgaagttttagtaacttctttaaAatcaatagctaaaataagta -35 -10 +1 |
| Evidence: |
[AIPP] [ICWHO] |
| Reference(s): |
[2] Huerta AM., et al., 2003 [1] Uppal S., et al., 2008 |
| Name: | cspE | |||||||||
| Gene(s): | cspE Genome Browser M3D Gene expression COLOMBOS | |||||||||
| Note(s): | The cspE gene is constitutively expressed at 37°C and is induced about threefold at both the transcript and the protein levels in response to cold shock. cspE is also regulated at the posttranscriptional level by RNAse E and temperature-dependent UTR secondary structures Uppal S,2008. Previously, cspE was shown to be involved in the regulation of the expression of some cold-induced genes Phadtare S, Tadigotla V, Shin WH, Sengupta A, Severinov K,2006; in particular, it might play an important role in the early stages of cold adaptation Uppal S,2008. The mRNA produced by the cspE gene has been observed mainly in the poles of the cell Kannaiah S, Livny J, Amster-Choder O,2019. |
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| Evidence: | [ICWHO] Inferred computationally without human oversight [LTED] Length of transcript experimentally determined |
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| Reference(s): | [1] Uppal S., et al., 2008 | |||||||||
| Promoter | ||||||||||
| Name: | cspEp2 | |||||||||
| +1: | 657250 | |||||||||
| Sigma Factor: | Sigma70 Sigmulon | |||||||||
| Distance from start of the gene: | 42 | |||||||||
| Sequence: |
tatcactttttagtaaagttacactggacaaagcgtaccacaattggtgtactggtaaccGacacagcatttgtgtctatt -35 -10 +1 |
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| Note(s): | cspEp2 has two transcription start sites (656472 and 656473, absolute position in the genome), which were identified at 37 and 15°C Uppal S,2008. | |||||||||
| Evidence: |
[AIPP] [ICWHO] [TIM] |
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| Reference(s): |
[2] Huerta AM., et al., 2003 [1] Uppal S., et al., 2008 |
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| Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
| proximal | CRP-cyclic-AMP | activator | cspEp2 | 657178 | 657200 | -61.5 | acatcaaaaaTAACGCGACTTTTATCACTTTTTagtaaagtta | nd | [GEA], [APIORCISFBSCS], [BPP], [SM] | [4] |
| Reference(s) |
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|---|---|
[AIPP] Automated inference of promoter position