RegulonDB RegulonDB 10.9: Operon Form
   

gcvR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: gcvR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: gcvR
Gene(s): gcvR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
[IMP] Inferred from mutant phenotype
Reference(s): [1] Ghrist AC., et al., 1998
Promoter
Name: gcvRp2
+1: 2599806
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 100
Sequence: acttcccgtgaacatgggccatcctctgtgcaaacaagtgtctcaatggtacgtttggtaTggcattaaaagcaagcagac
                           -35                    -10       +1                   
Note(s): gcvRp2 is the minor transcription start site for the gcvR gene, since it has been shown that nearly all of the gcvR mRNA transcript initiates from the primary promoter gcvRp1 Ghrist AC,1998 Its importance is still unclear, and if this promoter functions in vivo, it is at very low levels Ghrist AC,1998
Evidence: [IHBCE]
[TIM]
Reference(s): [1] Ghrist AC., et al., 1998


Transcription unit       
Name: gcvR
Gene(s): gcvR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
[IMP] Inferred from mutant phenotype
Reference(s): [1] Ghrist AC., et al., 1998
Promoter
Name: gcvRp
+1: 2599879
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 27
Sequence: aagcagacagaaccgttctgattgttgtatgcatgttttttttatgctttccttaagaacAactcaccccttaaaggaata
                         -35                    -10         +1                   
Note(s): gcvRp is the primary transcription start site for the gcvR gene, since approximately 90% of its expression initiates from this promoter Ghrist AC,1998
Evidence: [HIPP]
[ICWHO]
[IHBCE]
[IMP]
[RS-EPT-CBR]
[TIM]
Reference(s): [1] Ghrist AC., et al., 1998
[2] Huerta AM., et al., 2003
[3] Salgado H, et al., 2012





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