RegulonDB RegulonDB 11.1: Operon Form

uspB operon and associated TUs in Escherichia coli K-12 genome

Name: uspB
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: uspB
Gene(s): uspB   Genome Browser M3D Gene expression COLOMBOS
Note(s): uspB gene expression is upregulated upon L-valine addition (isoleucine starvation) in the cellular growth medium Gummesson B, Shah SA, Borum AS, Fessler M, Mitarai N, Sørensen MA, Svenningsen SL,2020.
Name: uspBp
+1: 3639848
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 128
Sequence: gaatatattgatagtggttaaccttctggaaaaaaaacaacctgatctcctacactatctAtagagccgctcgtatgttgg
                               -35                      -10 +1                   
Evidence: [COMP-AINF]
Reference(s): [1] Farewell A., et al., 1998
[2] Huerta AM., et al., 2003
[3] Kvint K., et al., 2000
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal IHF repressor uspBp 3639896 3639908 -54.0 ttttcgacatGAATATATTGATAgtggttaacc nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [1]
Allosteric regulation of RNA-polymerase
  Regulator Function Promoter target of RNApol Growth Conditions Note Evidence Reference
  ppGpp activation uspBp nd   [EXP-IEP-GENE-EXPRESSION-ANALYSIS] [3]
Evidence: [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis
Reference(s): [3] Kvint K., et al., 2000