RegulonDB RegulonDB 10.8: Operon Form
   

fhuE operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: fhuE
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: fhuE
Gene(s): fhuE   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Sauer M., et al., 1990
Promoter
Name: fhuEp
+1: 1161647
Distance from start of the gene: 96
Sequence: gctgaaaagacattctctgtttggtttacatgacaaatatgaatgcgtatatttctcattTgcatttacaaacaaaattat
Evidence: [HIPP]
Reference(s): [1] Sauer M., et al., 1990
Terminator(s)
Type: rho-independent
Sequence: tggggagactAAGGCAGCCAGATGGCTGCCTTttttacaggt
Reference(s): [1] Sauer M., et al., 1990
TF binding sites (TFBSs)
[Fur,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fur-Fe2+1 repressor fhuEp 1161624 1161642 15.0 tcatttgcatTTACAAACAAAATTATTCGcacactaaat nd [APIORCISFBSCS] [1], [2]
proximal Fur-Fe2+2 repressor fhuEp 1161648 1161666 -10.0 gacaaatatgAATGCGTATATTTCTCATTtgcatttaca nd [AIBSCS] [2]
Note(s): 1The regulatory effect of Fur on the promoter for fhuE is as of yet not known. However, we assigned a negative effect to this regulatory interaction based on two facts: (1) the protein's binding site is 16 bp downstream of the transcription start site; and (2) Fur is known to act, so far without exceptions, as a negative regulator.
2The regulatory effect of Fur on the promoter for fhuE is as of yet not known. However, we assigned a negative effect to this regulatory interaction based on two facts: (1) the protein's binding site is 16 bp downstream of the transcription start site; and (2) Fur is known to act, so far without exceptions, as a negative regulator.1The regulatory effect of Fur on the promoter for fhuE is as of yet not known. However, we assigned a negative effect to this regulatory interaction based on two facts: (1) the protein's binding site is 16 bp downstream of the transcription start site; and (2) Fur is known to act, so far without exceptions, as a negative regulator.
2The regulatory effect of Fur on the promoter for fhuE is as of yet not known. However, we assigned a negative effect to this regulatory interaction based on two facts: (1) the protein's binding site is 16 bp downstream of the transcription start site; and (2) Fur is known to act, so far without exceptions, as a negative regulator.


Evidence    

 [HIPP] Human inference of promoter position

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [AIBSCS] Automated inference based on similarity to consensus sequences


Reference(s)    

 [1] Sauer M., Hantke K., Braun V., 1990, Sequence of the fhuE outer-membrane receptor gene of Escherichia coli K12 and properties of mutants., Mol Microbiol 4(3):427-37

 [2] Newman DL., Shapiro JA., 1999, Differential fiu-lacZ fusion regulation linked to Escherichia coli colony development., Mol Microbiol 33(1):18-32

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