RegulonDB RegulonDB 10.9: Operon Form
   

narU operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: narU
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: narU
Gene(s): narU   Genome Browser M3D Gene expression COLOMBOS
Note(s): Activation of the narUZYWV cluster, which is poorly conserved even in Escherichia, represents a novel strategy to significantly improve osmotic stress tolerance. Precise control of the composition of OmpR-regulated membrane proteins is crucial for E. coli K-12 MG1655 viability Seo SW, Gao Y, Kim D, Szubin R, Yang J, Cho BK, Palsson BO,2017.
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: narUp1
+1: 1544124
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 64
Sequence: tttcttatctattctttcaatcagcacttcacccaattcatccttaattctaataactggCtattgcgccttacctcgtgt
                    -35                       -10           +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the promoters, whose transcription start sites were determined experimentally, present a distance of 6 nucleotides between the transcription start site and the -10 box.
Evidence: [HIPP]
[ICWHO]
Reference(s): [1] Chang L., et al., 1999
[2] Huerta AM., et al., 2003


Transcription unit       
Name: narU
Gene(s): narU   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: narUp2
+1: 1544163
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 103
Sequence: tctggctacttaatccccattctgcccccgcggttacgctttcttatctattctttcaatCagcacttcacccaattcatc
                           -35              -10             +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the promoters, whose transcription start sites were determined experimentally, present a distance of 6 nucleotides between the transcription start site and the -10 box.
Evidence: [HIPP]
[ICWHO]
Reference(s): [1] Chang L., et al., 1999
[2] Huerta AM., et al., 2003





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