RegulonDB RegulonDB 10.9: Operon Form

trxC operon and associated TUs in Escherichia coli K-12 genome

Name: trxC
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: trxC
Gene(s): trxC   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of the gene trxC is enhanced under high oxygen saturation (300%) in the absence of the superoxide dismutase proteins SodA and SodB Baez A,2013
Sulfane sulfur modifies OxyR at Cys199 to form a protein persulfide that in turn activates the expression of grxA, trxC, and katG promoters under both aerobic and anaerobic conditions 31421411
Evidence: [ICWHO] Inferred computationally without human oversight
Name: trxCp
+1: 2718675
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 60
Sequence: atcatacctattgaataaaacagattgttgtctggaacaatgtccccgataatatgtaacAtattagaaacataccggcgt
                            -35                   -10       +1                   
Evidence: [HIPP]
Reference(s): [1] Huerta AM., et al., 2003
[2] Ritz D., et al., 2000
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal OxyR activator trxCp 2718610 2718626 -57.0 ccaaagcctgCGACTATCATACCTATTGaataaaacag [APIORCISFBSCS], [BPP], [CEEUMA], [GEA], [IHBCE], [RSE] [2], [3]
proximal OxyR activator trxCp 2718632 2718648 -35.0 ctattgaataAAACAGATTGTTGTCTGGaacaatgtcc [APIORCISFBSCS], [BPP], [GEA] [2]