RegulonDB RegulonDB 10.10: Operon Form

trxC operon and associated TUs in Escherichia coli K-12 genome

Name: trxC
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: trxC
Gene(s): trxC   Genome Browser M3D Gene expression COLOMBOS
Note(s): The transcription of the gene trxC is enhanced under high oxygen saturation (300%) in the absence of the superoxide dismutase proteins SodA and SodB Baez A,2013
Sulfane sulfur modifies OxyR at Cys199 to form a protein persulfide that in turn activates the expression of grxA, trxC, and katG promoters under both aerobic and anaerobic conditions Hou N, Yan Z, Fan K, Li H, Zhao R, Xia Y, Xun L, Liu H,2019
Evidence: [ICWHO] Inferred computationally without human oversight
Name: trxCp
+1: 2718675
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 60
Sequence: atcatacctattgaataaaacagattgttgtctggaacaatgtccccgataatatgtaacAtattagaaacataccggcgt
                            -35                   -10       +1                   
Evidence: [HIPP]
Reference(s): [1] Huerta AM., et al., 2003
[2] Ritz D., et al., 2000
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal OxyR activator trxCp 2718610 2718626 -57.0 ccaaagcctgCGACTATCATACCTATTgaataaaaca [GEA], [RSE], [APIORCISFBSCS], [BPP], [CEEUMA], [IHBCE] [2], [3]
proximal OxyR activator trxCp 2718632 2718648 -35.0 ctattgaataAAACAGATTGTTGTCTGgaacaatgtc [GEA], [APIORCISFBSCS], [BPP] [2]