RegulonDB RegulonDB 10.9: Operon Form
   

yhfG-fic-pabA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yhfG-fic-pabA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: pabA
Gene(s): pabA   Genome Browser M3D Gene expression COLOMBOS
Promoter
Name: pabAp1
+1: 3490851
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 22
Sequence: ctgcagatgatatttagcaaagtggtaagcgaagccggggaatctgagtaaaatagcgcgGttcttttgtaccggagccgc
                      -35                        -10        +1                   
Evidence: [ICWHO]
[IMP]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[2] Tran PV., et al., 1990


Transcription unit       
Name: yhfG-fic-pabA
Gene(s): pabA, fic, yhfG   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
[PM] Polar mutation
Reference(s): [2] Tran PV., et al., 1990
Promoter
Name: yhfGp
+1: 3491648
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 28
Sequence: caatcttgcccgcgcttctgctctcccggcgtaacccggatttgccgcttatacttgtggCaaatggacacgttcagggag
                                                  -10       +1                   
Note(s): The -35 region of this promoter is not essential to fic gene transcription Hiratsu K,1995
Evidence: [CV(RPF/RS-EPT-CBR)]
[CV(RPF/TIM)]
[HIPP]
[IEP]
[IHBCE]
[IMP]
[RPF]
[RS-EPT-CBR]
[TIM]
Reference(s): [3] Bordes P., et al., 2000
[4] Hiratsu K., et al., 1995
[5] Salgado H, et al., 2012
[2] Tran PV., et al., 1990
[6] Utsumi R., et al., 1993




Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Tran PV., Bannor TA., Doktor SZ., Nichols BP., 1990, Chromosomal organization and expression of Escherichia coli pabA., J Bacteriol 172(1):397-410

 [3] Bordes P., Repoila F., Kolb A., Gutierrez C., 2000, Involvement of differential efficiency of transcription by esigmas and esigma70 RNA polymerase holoenzymes in growth phase regulation of the Escherichia coli osmE promoter., Mol Microbiol 35(4):845-53

 [4] Hiratsu K., Shinagawa H., Makino K., 1995, Mode of promoter recognition by the Escherichia coli RNA polymerase holoenzyme containing the sigma S subunit: identification of the recognition sequence of the fic promoter., Mol Microbiol 18(5):841-50

 [5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [6] Utsumi R., Kusafuka S., Nakayama T., Tanaka K., Takayanagi Y., Takahashi H., Noda M., Kawamukai M., 1993, Stationary phase-specific expression of the fic gene in Escherichia coli K-12 is controlled by the rpoS gene product (sigma 38)., FEMS Microbiol Lett 113(3):273-8


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