RegulonDB RegulonDB 10.8: Operon Form

paaXY operon and associated TUs in Escherichia coli K-12 genome

Name: paaXY
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: paaXY
Gene(s): paaX, paaY   Genome Browser M3D Gene expression COLOMBOS
Note(s): Based on the improved computational program DTI (Direct Information criterion), which is an extension of the concept of MI that allows investigators to measure the direction of information flow between two random variables, and DTInfer, a new R-package for the inference of gene regulatory networks from microarrays based on directed information, the paaY gene was identified as a new target of PaaX based on a high Z-score Kaleta C,2010 The paaABCDEFGHIJK and paaXY operons might be cotranscribed Kaleta C,2010
Evidence: [BTEI] Boundaries of transcription experimentally identified
[LTED] Length of transcript experimentally determined
Reference(s): [1] Fernandez C., et al., 2014
[2] Ferrandez A., et al., 1998
Name: paaXp
+1: 1463509
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 30
Sequence: ggccctggtggggtaaagcgccagggccagaagtcgatacgacctgtgctatgattcataAatcacaacaataacaacaga
                        -35                       -10       +1                   
Note(s): The -10 region of the paaX promoter shows good homology to the extended consensus promoter.
Evidence: [HIPP]
Reference(s): [2] Ferrandez A., et al., 1998
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PaaX repressor paaXp 1463500 1463538 10.5 acctgtgctaTGATTCATAAATCACAACAATAACAACAGACTGAAGCGAatgagtaaac nd [APIORCISFBSCS], [BPP] [1]