|Gene(s):||leuV, leuP, leuQ Genome Browser M3D Gene expression COLOMBOS|
|Note(s):||It is very probable that both valVW and leuQPV operons terminate in a Rho-dependent fashion, since the downstream sequences do not contain any recognizable Rho-independent transcription terminator structures Mohanty BK,2007.
A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for leuP . This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
|Evidence:||[BTEI] Boundaries of transcription experimentally identified
[LTED] Length of transcript experimentally determined
|Reference(s):|| Mohanty BK., et al., 2007|
|Sigma Factor:||Sigma70 Sigmulon|
|Distance from start of the gene:||31|
-35 -10 +1
|Type||Transcription factor||Function||Promoter||Binding Sites||Growth Conditions||Evidence (Confirmed, Strong, Weak)||Reference(s)|
|proximal||Fis||activator||leuQp||4606498||4606512||-73.0||gtttcctgatGGACATTTTTCCAGCaattacacct||nd||[APIORCISFBSCS], [BCE], [CV(GEA/ROMA)], [GEA], [IHBCE]||, |
 Verbeek H., Nilsson L., Baliko G., Bosch L., 1990, Potential binding sites of the trans-activator FIS are present upstream of all rRNA operons and of many but not all tRNA operons., Biochim Biophys Acta 1050(1-3):302-6