RegulonDB RegulonDB 11.1: Operon Form
   

ychQA-kdsA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ychQA-kdsA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: ychQA-kdsA
Gene(s): ychQ, ychA, kdsA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
[EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Strohmaier H., et al., 1995
Promoter
Name: ychQp
+1: 1266899
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 25
Sequence: catttatcctcgcggggtatcatgacgtcgaaacctgccgtgactatggtgataacgagcGcgtaacgctcggccgctatt
                      -35                    -10            +1                   
Evidence: [COMP-AINF]
[COMP-HINF]
[COMP-HINF-POSITIONAL-IDENTIFICATION]
[EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [2] Huerta AM., et al., 2003
[1] Strohmaier H., et al., 1995
Terminator(s)
Type: rho-independent
Sequence: cttgaaaaatAAAGTATTAGCGTTCTGCGTTAAGACTTTtttcatgggt
Reference(s): [3] Woisetschlager M., et al., 1987


Transcription unit       
Name: kdsA
Gene(s): kdsA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
Reference(s): [1] Strohmaier H., et al., 1995
Promoter
Name: kdsAp
+1: 1267854
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 311
Sequence: aatatcagcccgtcggcggaactgttttatgaagaccttgatgaagctgataacattgagGtaatccgcaaattgctggat
                          -35                      -10      +1                   
Evidence: [COMP-AINF]
[COMP-HINF-POSITIONAL-IDENTIFICATION]
[EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [2] Huerta AM., et al., 2003
[1] Strohmaier H., et al., 1995
[3] Woisetschlager M., et al., 1987
Terminator(s)
Type: rho-independent
Sequence: cttgaaaaatAAAGTATTAGCGTTCTGCGTTAAGACTTTtttcatgggt
Reference(s): [3] Woisetschlager M., et al., 1987


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-HINF] Inferred by a human based on computational evidence

 [COMP-HINF-POSITIONAL-IDENTIFICATION] Human inference of promoter position

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping


Reference(s)    

 [1] Strohmaier H., Remler P., Renner W., Hogenauer G., 1995, Expression of genes kdsA and kdsB involved in 3-deoxy-D-manno-octulosonic acid metabolism and biosynthesis of enterobacterial lipopolysaccharide is growth phase regulated primarily at the transcriptional level in Escherichia coli K-12., J Bacteriol 177(15):4488-500

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Woisetschlager M., Hogenauer G., 1987, The kdsA gene coding for 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase is part of an operon in Escherichia coli., Mol Gen Genet 207(2-3):369-73

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