RegulonDB RegulonDB 10.8: Operon Form
   

tpx operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: tpx
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: tpx
Gene(s): tpx   Genome Browser M3D Gene expression COLOMBOS
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Kim HK., et al., 1996
Promoter
Name: tpxp
+1: 1388844
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 33
Sequence: ctgcggattaagcgcaaatagcgtttgctgtgttattgacagttagcataaactaggtgtGacgttaactatatgtaaaca
                         -35                     -10        +1                   
Evidence: [HIPP]
[IMP]
[TIM]
Reference(s): [1] Kim HK., et al., 1996
TF binding sites (TFBSs)
[ArcA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ArcA-Phosphorylated repressor tpxp 1388859 1388873 -22.0 cgtttgctgtGTTATTGACAGTTAGcataaactag nd [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] [2]
[FNR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FNR repressor tpxp 1388856 1388869 -18.5 tgctgtgttaTTGACAGTTAGCATaaactaggtg nd [APIORCISFBSCS], [CV(GEA/ROMA)], [GEA] [2]


Evidence    

 [HIPP] Human inference of promoter position

 [IMP] Inferred from mutant phenotype

 [TIM] Transcription initiation mapping

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [CV(GEA/ROMA)] cross validation(GEA/ROMA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Kim HK., Kim SJ., Lee JW., Lee JW., Cha MK., Kim IH., 1996, Identification of promoter in the 5'-flanking region of the E. coli thioredoxin-linked thiol peroxidase gene: evidence for the existence of oxygen-related transcriptional regulatory protein., Biochem Biophys Res Commun 221(3):641-6

 [2] Kim SJ., Han YH., Kim IH., Kim HK., 1999, Involvement of ArcA and Fnr in expression of Escherichia coli thiol peroxidase gene., IUBMB Life 48(2):215-8

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