RegulonDB RegulonDB 10.8: Operon Form
   

htpX operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: htpX
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: htpX
Gene(s): htpX   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for htpX . This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Kornitzer D., et al., 1991
Promoter
Name: htpXp
+1: 1912618
Sigma Factor: Sigma32 Sigmulon
Distance from start of the gene: 42
Sequence: tctggtgacttacgcactatccagacttgaaaatagtcgcgtaacccatacgatgtgggtAtcgcatattgcgttttgtta
                           -35              -10             +1                   
Note(s): The distance between the -10 region and the -35 region (12 nucleotides) is slightly shorter than the spacing in the other heat shock promoters (13-15 nucleotides), whereas the distance between the -10 region and the transcription start site is 1-2 nucleotides longer than this distance in the other heat shock promoters.
Evidence: [AIPP]
[CV(RS-EPT-CBR/TA)]
[CV(TA/TIM)]
[HIPP]
[IDA]
[IEP]
[RS-EPT-CBR]
[TIM]
Reference(s): [1] Kornitzer D., et al., 1991
[2] Nonaka G., et al., 2006
[3] Salgado H, et al., 2012
[4] Wade JT., et al., 2006
Terminator(s)
Type: rho-independent
Sequence: gggcataaaaAAAGCGCGTCGATCAGGACGCGCTTTTTagtatttact
Reference(s): [1] Kornitzer D., et al., 1991


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -18.7 1912731 1912762 agtaatatcaATCAGGCACAAGAAATTGTGCCTGATTTTTTaacagcgaca
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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