RegulonDB RegulonDB 11.1: Operon Form
   

lrhA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: lrhA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: lrhA
Gene(s): lrhA   Genome Browser M3D Gene expression COLOMBOS
Reference(s): [1] Bongaerts J., et al., 1995
Promoter
Name: lrhAp
+1: 2406656
Distance from start of the gene: 15
Sequence: ttacaaatggaattgcttgtttgtgtgtgcacagcattaaccagctcagtatgagccgccAgtaagtgataatatatgata
Evidence: [COMP]
Reference(s): [1] Bongaerts J., et al., 1995
TF binding sites (TFBSs)
[LrhA,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd LrhA activator lrhAp nd nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -9.7 2406757 2406796 taacggaacaATGTGAGTCGCTTTTTTAGTGCAACTCATATGCATTTTTactttcgtcc
  anti-terminator -3.9 2406786 2406826 gatatattctGTGATCTACTTCAGGCATTATAACGGAACAATGTGAGTCGcttttttagt
  anti-anti-terminator -6.1 2406816 2406866 agaaaagagtGAGTAACTTAATAGATATGCGATCCCTGAAGATATATTCTGTGATCTACTtcaggcatta
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"


Evidence    

 [COMP] Inferred by computational analysis

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] Binding of purified proteins


Reference(s)    

 [1] Bongaerts J., Zoske S., Weidner U., Unden G., 1995, Transcriptional regulation of the proton translocating NADH dehydrogenase genes (nuoA-N) of Escherichia coli by electron acceptors, electron donors and gene regulators., Mol Microbiol 16(3):521-34

 [2] Lehnen D., Blumer C., Polen T., Wackwitz B., Wendisch VF., Unden G., 2002, LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli., Mol Microbiol 45(2):521-32

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