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Name: | upp-uraA |
Gene(s): | uraA, upp Genome Browser M3D Gene expression COLOMBOS |
Note(s): | This operon is regulated by pyrimidine-mediated reiterative transcription. There is a putative internal terminator between upp and uraA. The intergenic region of upp-purMN protects against bacterial cell death via both type I and type II covalent topoisomerase-DNA cleavage complexes Liu IF,2011 Deletion of the binding site for FNR and PurR from the intergenic region of upp-purMN decreases the protective effect, inducing lethality via titration Liu IF,2011 |
Evidence: | [BTEI] Boundaries of transcription experimentally identified [PM] Polar mutation |
Reference(s): |
[1] Andersen PS., et al., 1995 [2] Tu AH., et al., 1997 |
Promoter | |
Name: | uppp |
+1: | 2620909 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 37 |
Sequence: |
ttttgactaaagtcaacgaaaagaatattgccgccttgaagaaaggaggtataatccgtcGattttttttgtggctgcccc -35 -10 +1 |
Evidence: |
[HIPP] [ICWHO] [IDA] [TIM] |
Reference(s): |
[3] Andersen PS., et al., 1992 [4] Cheng Y., et al., 2001 [5] Huerta AM., et al., 2003 [6] Imashimizu M., et al., 2020 [2] Tu AH., et al., 1997 |
Reference(s) |
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