RegulonDB RegulonDB 11.1: Operon Form

umuDC operon and associated TUs in Escherichia coli K-12 genome

Name: umuDC
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: umuDC
Synonym(s): OP00250
Gene(s): umuD, umuC   Genome Browser M3D Gene expression COLOMBOS
Note(s): umuDC, among other genes that form the SOS response regulon, belong to the most abundant class of upregulated genes in two MG1655 lysogens carrying closely related Stx2a phages O104 and PA8 1208335|.
Evidence: [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Fernandez De Henestrosa AR., et al., 2000
[2] Opperman T., et al., 1996
Name: umuDp
+1: 1230738
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 29
Sequence: gacaaatattgatagcctgaatcagtattgatctgctggcaagaacagactactgtatatAaaaacagtataacttcaggc
                            -35                    -10      +1                   
Evidence: [COMP-AINF]
Reference(s): [3] Huerta AM., et al., 2003
[4] Kitagawa Y., et al., 1985
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor umuDp 1230708 1230727 -20.5 atcagtattgATCTGCTGGCAAGAACAGACtactgtatat nd [COMP-HINF-SIMILAR-TO-CONSENSUS] nd [4], [5]
proximal LexA repressor umuDp 1230728 1230747 -0.5 aagaacagacTACTGTATATAAAAACAGTAtaacttcagg nd [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] nd [4], [5]