RegulonDB RegulonDB 11.1: Operon Form

panBC operon and associated TUs in Escherichia coli K-12 genome

Name: panBC
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit       
Name: panBC
Gene(s): panC, panB   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for panC . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020.
Evidence: [EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Jones CE., et al., 1993
[2] Merkel WK., et al., 1996
[3] Vallari DS., et al., 1985
Name: panBp
+1: 149630
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 29
Sequence: tggcagtgctgctacggataaatcattgcccccaccaatgtgactgataaaatgccagacAgcacaacatcaatttatcag
                               -35                   -10    +1                   
Note(s): We assigned a putative transcriptional start site to this promoter based on the observation that the majority of the promoters, whose transcriptional start sites were determined experimentally, present a distance of 6 nucleotides between the transcriptional start site and the -10 box Harley CB, Reynolds RP,1987.
Evidence: [COMP-AINF]
Reference(s): [4] Huerta AM., et al., 2003
[1] Jones CE., et al., 1993
[5] Salgado H, et al., 2012