RegulonDB RegulonDB 10.9: Operon Form
   

glpD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: glpD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: glpD
Synonym(s): OP00038
Gene(s): glpD   Genome Browser M3D Gene expression COLOMBOS
Reference(s): [1] Iuchi S., et al., 1990
Promoter
Name: glpDp
+1: 3561971
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 42
Sequence: tcactctaaaatgttttttcaatgttacctaaagcgcgattctttgctaatatgttcgatAacgaacatttatgagcttta
                         -35                    -10         +1                   
Note(s): In a gene expression analysis, RpoS positively regulated the glpD gene in the stationary phase. Its effect could be indirect Becker-Hapak M,1995
Evidence: [ICWHO]
[TIM]
Reference(s): [2] Huerta AM., et al., 2003
[3] Yang B., et al., 1996
[4] Ye SZ., et al., 1988
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd ArcA-Phosphorylated repressor glpDp nd nd nd nd nd [BPP], [GEA], [IGI] [1]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP activator glpDp 3561897 3561918 -63.5 ataaacgccaTAATGTTATACATATCACTCTAAaatgtttttt nd [APIORCISFBSCS], [BPP], [GEA] [4], [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal GlpR repressor glpDp 3561961 3561980 -0.5 tctttgctaaTATGTTCGATAACGAACATTTatgagcttta nd [APIORCISFBSCS], [BPP], [GEA] [3], [4]
proximal GlpR repressor glpDp 3561980 3561999 19.5 taacgaacatTTATGAGCTTTAACGAAAGTGaatgagggca nd [APIORCISFBSCS], [BPP], [GEA] [3], [4]
remote GlpR repressor glpDp 3562375 3562394 414.5 cgggatcaacTGGTTTGCGTTTTGGCGCAAAttcagtgtta nd [APIORCISFBSCS], [BPP], [GEA], [SM] [3]
remote GlpR4 repressor glpDp 3562416 3562435 455.5 aaaccggaaaTTAAGCGCGGATTCGAATATTctgactgttg nd [APIORCISFBSCS], [BPP], [GEA], [SM] [3]
Note(s): 4Although the internal operators required sites at +1 and +20 for repression in vivo, these sites were not required to demonstrate the binding of GlpR to sites +415.5 and +456.5.5Although the internal operators required sites at +1 and +20 for repression in vivo, these sites were not required to demonstrate the binding of GlpR to sites +415.5 and +456.5.





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