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Name: | malQ |
Gene(s): | malQ Genome Browser M3D Gene expression COLOMBOS |
Evidence: | [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified |
Promoter | |
Name: | malQp |
+1: | 3550399 |
Sigma Factor: | Sigma24 Sigmulon |
Distance from start of the gene: | 329 |
Sequence: |
aaaatatctttatttttggtcataccgtggaacaagtgaaggcaattctggccaaaggctAcgacccggtgaaatggcgga -35 -10 +1 |
Evidence: |
[COMP-AINF] [COMP-AINF-POSITIONAL-IDENTIFICATION] [COMP-AINF-SIMILAR-TO-CONSENSUS] [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] |
Reference(s): |
[1] Huerta AM., et al., 2003 [2] Rhodius VA., et al., 2005 |
Name: | malPQ | ||||||||||
Synonym(s): | OP00049 | ||||||||||
Gene(s): | malQ, malP Genome Browser M3D Gene expression COLOMBOS | ||||||||||
Note(s): | Through DNase footprinting analyses, Danot and Raibaud (1994) showed that CRP binds at the promoter region of malPQ, centered at -93.5 upstream of the transcription start site of malPp Danot O,1994 However, the destruction of the CRP site has no effect on the transcription of the operon malPQ. In this way, the effect of CRP on the expression of malPQ might be indirect and mediated by MalT as a direct regulator Danot O,1994. Camakaris H,1982. Chapon C,1982 A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for malP . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020. |
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Reference(s): |
[3] Chao J., et al., 1974 [4] Danot O., et al., 1994 [5] Foglino M., et al., 1987 |
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Promoter | |||||||||||
Name: | malPp | ||||||||||
+1: | 3552510 | ||||||||||
Sigma Factor: | Sigma70 Sigmulon | ||||||||||
Distance from start of the gene: | 37 | ||||||||||
Sequence: |
tccctgcctaatcccccgcaggatgaggaaggtcaacatcgagcctggcaaactagcgatAacgttgtgttgaaaatctaa -35 -10 +1 |
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Evidence: |
[COMP-AINF] [COMP-AINF-POSITIONAL-IDENTIFICATION] [EXP-IMP] [RS-EPT-CBR] |
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Reference(s): |
[6] Debarbouille M., et al., 1982 [7] Gutierrez C., et al., 1984 [1] Huerta AM., et al., 2003 [8] Salgado H, et al., 2012 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
remote | FNR | activator | malPp | 3552631 | 3552644 | -127.5 | ttgcattgatTTGATGCTAATCCTgtggtttgca | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-AINF-SIMILAR-TO-CONSENSUS] | W | [9] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
proximal | MalT-maltotriose-ATP | activator | malPp | 3552543 | 3552553 | -37.5 | ctaatcccccGCAGGATGAGGaaggtcaaca | nd | [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] | C | [4] |
proximal | MalT-maltotriose-ATP | activator | malPp | 3552566 | 3552576 | -60.5 | tcatccccgcAACTCCTCCCTgcctaatccc | nd | [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS], [EXP-IMP-SITE-MUTATION] | C | [4] |
proximal | MalT-maltotriose-ATP | activator | malPp | 3552579 | 3552589 | -73.5 | cacatttcctTGCTCATCCCCgcaactcctc | nd | [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] | nd | [4] |
remote | MalT-maltotriose-ATP | activator | malPp | 3552601 | 3552611 | -95.5 | actagctttaAGTGGTTGAGAtcacatttcc | nd | [COMP-AINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] | nd | nd |
Reference(s) |
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