RegulonDB RegulonDB 10.10: Operon Form
   

betIBA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: betIBA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: betIBA
Synonym(s): OP00155
Gene(s): betA, betB, betI   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for betA . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020.
Reference(s): [1] Lamark T., et al., 1996
[2] Rkenes TP., et al., 1996
Promoter
Name: betIp
+1: 329361
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 27
Sequence: cgtaacaattaagacacattttatattgaacgtccaatcaataaccgctttaatagataaAcaccgctgatgaatggagtg
                          -35                      -10      +1                   
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [3] Huerta AM., et al., 2003
[1] Lamark T., et al., 1996
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ArcA-phosphorylated repressor betIp 329360 329374 -6.0 tcaataaccgCTTTAATAGATAAACaccgctgatg nd [BCE] [1], [5]
proximal ArcA-phosphorylated repressor betIp 329428 329442 -74.0 cactgttattGTTACTATTTAAAATcaaattcgta nd [GEA], [BCE] nd
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal BetI repressor betIp 329381 329400 -30.0 agacacatttTATATTGAACGTCCAATCAAtaaccgcttt nd [GEA], [APIORCISFBSCS], [BPP], [GS] [1], [2], [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd Cra activator betIp nd nd nd nd nd [GEA], [BPP] [6]





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