Name: |
malS |
Synonym(s): |
OP00184 |
Gene(s): |
malS
Genome Browser
M3D Gene expression
COLOMBOS
|
Note(s): |
The malS gene, which codes for a periplasmic α-amylase, is an isolated gene Freundlieb S,1986, and it is regulated by the maltose regulator, MalT Freundlieb S,1986, the catabolite repressor, Crp Bukau B,1986, and the Mg deprivation response cognate, PhoP Monsieurs P,2005. Genes flanking malS are encoded in opposite directions: the downstream gene,avtA, which codes for an alanine-valine transaminase Wang MD,1987, and the bax gene. |
Evidence: |
[COMP-AINF-SINGLE-DIRECTON] Automated inference that a single-gene directon is a transcription unit |
Reference(s): |
[1] Bukau B., et al., 1986 [2] Freundlieb S., et al., 1986 [3] Monsieurs P., et al., 2005 [4] Otsuka J., et al., 1996 [5] Schneider E., et al., 1992 [6] Wang MD., et al., 1987
|
Promoter |
|
Name: |
malSp |
+1: |
3737470 |
Sigma Factor: |
Sigma70 Sigmulon |
Distance from start of the gene: |
27
|
Sequence: |
cctgtggacttaccgctcagggatgagttttgtttggcttatcgctggcaaactgtctgaAatcgcagcaataaggactca -35 -10 +1
|
Evidence: |
[COMP-AINF] [EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
|
Reference(s): |
[7] Huerta AM., et al., 2003 [5] Schneider E., et al., 1992
|
Terminator(s) |
|
Type: |
rho-independent |
Sequence: |
aacagtaactTTTCCGGCTTCCCGTTCGTCAGTACCTCGGGAAGCCGCCAAccaggataaa |
Reference(s): |
[5] Schneider E., et al., 1992
|
Type: |
rho-independent |
Sequence: |
cagccctaatCAGCGTTGCAGGATAAAGCACCGCTCactcttcaac |
Reference(s): |
[5] Schneider E., et al., 1992
|
Transcription factor |
Function |
Promoter |
Binding Sites |
Evidence (Confirmed, Strong, Weak) |
Reference(s) |
LeftPos |
RightPos |
Central Rel-Pos |
Sequence |
CRP-cyclic-AMP |
activator |
malSp |
3737228
|
3737250
|
-231.5
|
tttttcacaaATTTGAGAGTTGAATCTCAAATCatatcaaaaa
|
[EXP-IEP-GENE-EXPRESSION-ANALYSIS]
|
[8]
|
PhoP-phosphorylated |
activator |
malSp |
3737301
|
3737317
|
-161.0
|
caaatctgaaACTATGTCACGTGTTAAcgattcagat
|
[EXP-IEP-GENE-EXPRESSION-ANALYSIS]
|
[3]
|
MalT-maltotriose-ATP |
activator |
malSp |
3737391
|
3737400
|
-74.5
|
gcgcgagatcGCTCACCCTTgcttctcatc
|
nd
|
nd
|
MalT-maltotriose-ATP |
activator |
malSp |
3737404
|
3737413
|
-61.5
|
cacccttgctTCTCATCCTGtggacttacc
|
nd
|
nd
|
MalT-maltotriose-ATP |
activator |
malSp |
3737428
|
3737437
|
-37.5
|
cttaccgctcAGGGATGAGTtttgtttggc
|
nd
|
nd
|