RegulonDB RegulonDB 10.8: Operon Form
   

ugpBAECQ operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ugpBAECQ
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: ugpBAECQ
Gene(s): ugpQ, ugpC, ugpE, ugpA, ugpB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The ugpBAECQ genes are contiguous and their products are functionally related.
The expression of the gene ugpB is increased under acidic growth conditions in aerobiosis but not in microaerobiosis Marzan LW,2013 The increased expression appears to be caused by the transcription factor PhoB Marzan LW,2013
Evidence: [IC] Inferred by curator
Reference(s): [1] Overduin P., et al., 1988
Promoter
Name: ugpBp1
+1: 3592378
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 53
Sequence: tatcttacaaatgtaacaaaaaagttatttttctgtaattcgagcatgtcatgttaccccGcgagcataaaacgcgtgaat
                             -35                  -10       +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [2] Kasahara M., et al., 1991
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PhoB-Phosphorylated activator ugpBp1 3592399 3592417 -30.0 tgtaacaaaaAAGTTATTTTTCTGTAATTcgagcatgtc nd [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA] [2], [3]
proximal PhoB-Phosphorylated activator ugpBp1 3592421 3592439 -52.0 tgacaccttaCTATCTTACAAATGTAACAaaaaagttat nd [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA] [2], [3]


Transcription unit          
Name: ugpBAECQ
Gene(s): ugpQ, ugpC, ugpE, ugpA, ugpB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The ugpBAECQ genes are contiguous and their products are functionally related.
Evidence: [IC] Inferred by curator
Reference(s): [1] Overduin P., et al., 1988
Promoter
Name: ugpBp2
+1: 3592426
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 101
Sequence: ttccctcacccacgccgtcaccgccttgtcatctttctgacaccttactatcttacaaatGtaacaaaaaagttatttttc
                         -35                  -10           +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [2] Kasahara M., et al., 1991
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP activator ugpBp2 3592442 3592463 -26.5 gccgtcaccgCCTTGTCATCTTTCTGACACCTtactatctta nd [APIORCISFBSCS], [BPP] [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PhoB-Phosphorylated repressor ugpBp2 3592421 3592439 -4.0 tgacaccttaCTATCTTACAAATGTAACAaaaaagttat nd [APIORCISFBSCS], [BPP], [CV(CHIP-SV/GEA/ROMA)], [CV(GEA/ROMA)], [GEA] [2], [3]
proximal PhoB-Phosphorylated repressor ugpBp2 3592443 3592461 -26.0 cgtcaccgccTTGTCATCTTTCTGACACCttactatctt nd [APIORCISFBSCS], [BPP] [2]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -12.7 3590933 3590957 tcgcgtgtagGCCGGATAAGCGAAGCGCATCCGGcacagttcag
  terminator -6.2 3592352 3592365 agcataaaacGCGTGAATTCGCGcattcggtac
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





RegulonDB