RegulonDB RegulonDB 10.9: Operon Form
   

lysC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: lysC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: lysC
Gene(s): lysC   Genome Browser M3D Gene expression COLOMBOS
Note(s): Repression of lysC is through a riboswitch mechanism that directs lysine to the 5'-terminal part of the lysC mRNA Bouvier J,2008
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: lysCp1
+1: 4233539
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 306
Sequence: atgaaaaatccgcatgaccccatcgttgacaaccgccccgctcaccctttatttataaatGtactacctgcgctagcgcag
                           -35                        -10   +1                   
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [1] Cassan M., et al., 1983
[2] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd ArgP activator lysCp1 nd nd nd nd nd [BPP], [GEA], [IGI] [3]


Transcription unit       
Name: lysC
Gene(s): lysC   Genome Browser M3D Gene expression COLOMBOS
Note(s): Repression of lysC is through a riboswitch mechanism that directs lysine to the 5'-terminal part of the lysC mRNA Bouvier J,2008
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: lysCp2
+1: 4233616
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 383
Sequence: ccgttagcgtaatgttgagtgtaaacccttagcgcagtgaagcatttattagctgaactaCtgaccgccaggagtggatga
                    -35                        -10          +1                   
Evidence: [HIPP]
[ICWHO]
[TIM]
Reference(s): [2] Huerta AM., et al., 2003
[4] Liao HH., et al., 1998





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