RegulonDB RegulonDB 10.9: Operon Form
   

cspI operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: cspI
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: cspI
Gene(s): cspI   Genome Browser M3D Gene expression COLOMBOS
Note(s): Expression levels of cspI, ypjB, and yhjX genes were repressed by overproduction of YehT Kraxenberger T,2012 Insomuch as all of these genes lack any LytTR-like sequence motif, it is probable that the effect of YehT on these genes is indirect Kraxenberger T,2012
In spite of showing a match to the consensus CRP, cspB, cspG, and cspI are regulated indirectly by CRP-cAMP during growth at 37oC as well as 15oC Uppal S,2015 It is probable that putative sites in these genes have become degenerate and have lost the binding function during the evolutionary process Uppal S,2015
cspI gene is highly expressed in long-term stationary phase (LTSP) Kram KE,2020
Promoter
Name: cspIp2
+1: 1638712
Distance from start of the gene: 45
Sequence: attttattatttgtacctcttgagatttccttgttggtttttctctctgatattttttttCggaccattctgcccaagggc
Note(s): The transcription start site for cspIp2 was determined by 5-RACE; however, the experimental data were not provided in the report Kraxenberger T,2012
Evidence: [TIM]
Reference(s): [1] Kraxenberger T., et al., 2012


Transcription unit          
Name: cspI
Gene(s): cspI   Genome Browser M3D Gene expression COLOMBOS
Note(s): The cspI gene was significantly upregulated in bacterial cells associated with lettuce roots in a microarray analysis Hou Z,2012.
In spite of showing a match to the consensus CRP, cspB, cspG, and cspI are regulated indirectly by CRP-cAMP during growth at 37oC as well as 15oC Uppal S,2015 It is probable that putative sites in these genes have become degenerate and have lost the binding function during the evolutionary process Uppal S,2015
The cspI gene is highly expressed in long-term stationary phase (LTSP) Kram KE,2020
Promoter
Name: cspIp
+1: 1638812
Distance from start of the gene: 145
Sequence: gtgtttttctttacaaaagtaatccttgctatgggtggttaatcatgcgttaatggtgttCtggtttgttacaaatttatc
Evidence: [TIM]
Reference(s): [2] Wang N., et al., 1999
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote BasR-Phosphorylated activator cspIp 1638940 1638959 -137.5 ttccatgagcCAAAATTCCTGAAATCTTAAGggtaagataa nd [APIORCISFBSCS], [BPP] [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote Fis repressor cspIp 1638757 1638771 49.0 cattgttataATTTTATTATTTGTACctcttgagat nd [AIBSCS], [GEA] [4]
remote Fis repressor cspIp 1638765 1638779 41.0 gaagcagtcaTTGTTATAATTTTATTatttgtacct nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638792 1638806 14.0 gtgttctggtTTGTTACAAATTTATCtgaagcagtc nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638825 1638839 -20.0 tccttgctatGGGTGGTTAATCATGCgttaatggtg nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638888 1638902 -83.0 tgacacgtttTATTAATAAATAAAGCtattctttca nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638893 1638907 -88.0 cagaatgacaCGTTTTATTAATAAATaaagctattc nd [AIBSCS], [GEA] [4]





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