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| Operon |  |
|---|---|
| Name: | yeaGH |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | yeaGH |
| Gene(s): | yeaG, yeaH Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | The yeaGH operon is highly expressed during the initial adaptive response to nitrogen starvation. It is also highly expressed in response to diverse stresses, including low pH Weber H,2005 hyperosmotic conditions Rozen Y, Belkin S,2001 entry into stationary phase Weber H,2005 nitrogen starvation Brown DR,2014 sulfur limitation Gyaneshwar P,2005 growth in biofilms Schembri MA, Kjaergaard K, Klemm P,2003 and exposure to the antimicrobial peptide polymyxin B Erickson KD, Detweiler CS,2006 It is conserved across several bacterial species, especially among Enterobacteriaceae, including species pathogenic to plants or animals Brown DR,2014. Figueira R,2015. Zimmer DP,2000 and alongside relA it constitutes a new branch in the Ntr response Switzer A, Brown DR, Wigneshweraraj S,2018 |
| Evidence: | [IC] Inferred by curator |
| Promoter | |
| Name: | yeaGp2 |
| +1: | 1866765 |
| Distance from start of the gene: | 143 |
| Sequence: |
ccgtgcaggcaagttttccatttgccatctacgcttaattttgaaggtgtatcaccgggcAcgttgttctcatcgtcgata |
| Evidence: |
[HTTIM]  
|
| Reference(s): | [1] Mendoza-Vargas A., et al., 2009 |
| Name: | yeaGH |
| Gene(s): | yeaG, yeaH Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | The yeaGH operon is highly expressed during the initial adaptive response to nitrogen starvation. It is also highly expressed in response to diverse stresses, including low pH Weber H,2005 hyperosmotic conditions Rozen Y, Belkin S,2001 entry into stationary phase Weber H,2005 nitrogen starvation Brown DR,2014 sulfur limitation Gyaneshwar P,2005 growth in biofilms Schembri MA, Kjaergaard K, Klemm P,2003 and exposure to the antimicrobial peptide polymyxin B Erickson KD, Detweiler CS,2006 It is conserved across several bacterial species, especially among Enterobacteriaceae, including species pathogenic to plants or animals Brown DR,2014. Figueira R,2015. Zimmer DP,2000 and alongside relA it constitutes a new branch in the Ntr response Switzer A, Brown DR, Wigneshweraraj S,2018 |
| Reference(s): | [2] Zimmer DP., et al., 2000 |
| Promoter | |
| Name: | yeaGp1 |
| +1: | 1866815 |
| Sigma Factor: | Sigma54 Sigmulon |
| Distance from start of the gene: | 93 |
| Sequence: |
atcaccgggcacgttgttctcatcgtcgataaaatggcatgagagttgctgtgttttagcAagagacgtcgttcagtttac -24 -12 +1 |
| Note(s): | We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999. |
| Evidence: |
[AIBSCS] [AIPP] [ICWHO] |
| Reference(s): |
[3] Huerta AM., et al., 2003 [4] Reitzer L., et al., 2001 |
| Reference(s) |
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|---|---|
[HTTIM] High-throughput transcription initiation mapping