RegulonDB RegulonDB 10.9: Operon Form
   

mngAB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mngAB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: mngAB
Gene(s): mngA, mngB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Sampaio MM., et al., 2004
Promoter
Name: mngAp
+1: 765811
Sigma Factor: Sigma32 Sigmulon
Distance from start of the gene: 173
Sequence: ctgacgccaaactctgtttgtagcgctgattcagtgggtaacgcatcgccaggtttaagcTcgccacgcgcaatttgttca
                              -35              -10          +1                   
Evidence: [HIPP]
[IC]
[ICWHO]
Reference(s): [2] Gama-Castro S., et al., 2008
[3] Huerta AM., et al., 2003
[1] Sampaio MM., et al., 2004
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote MngR repressor mngAp 765890 765911 90.5 agtatctcatTAATACGAATTTAACCATTATGCccgataaatt nd [APIORCISFBSCS], [BPP], [APIORCISFBSCS], [BPP] [1], [4]
remote MngR repressor mngAp 765934 765955 134.5 atcctgtaaaTAATACAAATACAATACAAATAAtttcaatcaa nd [APIORCISFBSCS], [BPP], [APIORCISFBSCS], [BPP], [GEA] [1], [4]


Transcription unit       
Name: mngB
Gene(s): mngB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IEP] Inferred from expression pattern
Reference(s):
Promoter
Name: mngBp2
+1: 767795
Distance from start of the gene: 183
Sequence: aacgggcgctattgtcggtgcgatgaatatcggcctttcgacacccggtgccggcattttCtcgctctttttacttcatga
Evidence: [RSE]
[TIM]
Reference(s):


Transcription unit       
Name: mngB
Gene(s): mngB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IEP] Inferred from expression pattern
Reference(s): [6] Li Z., et al., 2019
Promoter
Name: mngBp
+1: 767825
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 153
Sequence: cggcctttcgacacccggtgccggcattttctcgctctttttacttcatgataatggcgcGggcggtgttatggcggcaat
                                                  -10       +1                   
Evidence: [ICWHO]
[RSE]
[TIM]
Reference(s): [6] Li Z., et al., 2019




Reference(s)    

 [1] Sampaio MM., Chevance F., Dippel R., Eppler T., Schlegel A., Boos W., Lu YJ., Rock CO., 2004, Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor., J Biol Chem 279(7):5537-48

 [2] Gama-Castro S., Jimenez-Jacinto V., Peralta-Gil M., Santos-Zavaleta A., Penaloza-Spinola MI., Contreras-Moreira B., Segura-Salazar J., Muniz-Rascado L., Martinez-Flores I., Salgado H., Bonavides-Martinez C., Abreu-Goodger C., Rodriguez-Penagos C., Miranda-Rios J., Morett E., Merino E., Huerta AM., Trevino-Quintanilla L., Collado-Vides J., 2008, RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation., Nucleic Acids Res 36(Database issue):D120-4

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Quail MA., Dempsey CE., Guest JR., 1994, Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli., FEBS Lett 356(2-3):183-7

 [5] null, 2018, Courses and Conferences., J Am Geriatr Soc 66(12):2437-2438

 [6] Li Z., Pan Q., Xiao Y., Fang X., Shi R., Fu C., Danchin A., You C., 2019, Deciphering global gene expression and regulation strategy in Escherichia coli during carbon limitation., Microb Biotechnol 12(2):360-376


RegulonDB