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| Operon |  |
|---|---|
| Name: | hemL |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | hemL |
| Gene(s): | hemL Genome Browser M3D Gene expression COLOMBOS |
| Evidence: | [AISGDTU] Automated inference that a single-gene directon is a transcription unit |
| Promoter | |
| Name: | hemLp1 |
| +1: | 174902 |
| Sigma Factor: | Sigma28 Sigmulon |
| Distance from start of the gene: | 20 |
| Sequence: |
gatgtttgacgagtatttaacttgttatgaataacatagaatagcagccattcactttttCtacgaatcaggaaccctcca -35 -10 +1 |
| Note(s): | The sequence of this promoter has been defined, by computational analyses, from the consensus sequence of the σ28 (σF) promoters: TAAAGTTT in the -35 box and GCCGATAA in the -10 box Yu HH,2006. Thus, we assigned a putative transcription start site for this promoter based on the observation that the majority of the σ28 promoters, determined experimentally, present an important -10 motif (5'-CGA-3') at the positions -12 to -10 and a distance of 6 nucleotides between the transcription start site and the -10 box 16855242. Yu HH,2006. Park K,2001. |
| Evidence: |
[HIPP] [ICWHO] [IEP] |
| Reference(s): |
[1] Huerta AM., et al., 2003 [2] Zhao K., et al., 2007 |
| Name: | hemL | |||||||||
| Gene(s): | hemL Genome Browser M3D Gene expression COLOMBOS | |||||||||
| Evidence: | [AISGDTU] Automated inference that a single-gene directon is a transcription unit | |||||||||
| Promoter | ||||||||||
| Name: | hemLp | |||||||||
| +1: | 174921 | |||||||||
| Sigma Factor: | Sigma28 Sigmulon | |||||||||
| Distance from start of the gene: | 39 | |||||||||
| Sequence: |
gcaccagtacaagcagcctgatgtttgacgagtatttaacttgttatgaataacatagaaTagcagccattcactttttct -35 -10 +1 |
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| Evidence: |
[ICWHO] [TIM] |
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| Reference(s): |
[1] Huerta AM., et al., 2003 [3] Minagawa S., et al., 2003 |
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| Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
| proximal | PhoP-Phosphorylated | activator | hemLp | 174944 | 174960 | -31.0 | aagcagcctgATGTTTGACGAGTATTTAacttgttatg | nd | [APIORCISFBSCS], [BPP], [GEA] | [3] |
| Name: | hemL |
| Gene(s): | hemL Genome Browser M3D Gene expression COLOMBOS |
| Evidence: | [AISGDTU] Automated inference that a single-gene directon is a transcription unit |
| Promoter | |
| Name: | hemLp2 |
| +1: | 174941 |
| Sigma Factor: | Sigma28 Sigmulon |
| Distance from start of the gene: | 59 |
| Sequence: |
tactctaagaaatcaggattgcaccagtacaagcagcctgatgtttgacgagtatttaacTtgttatgaataacatagaat -35 -10 +1 |
| Note(s): | The sequence of this promoter has been defined, by computational analyses, from the consensus sequence of the σ28 (σF) promoters: TAAAGTTT in the -35 box and GCCGATAA in the -10 box Yu HH,2006. Thus, we assigned a putative transcription start site for this promoter based on the observation that the majority of the σ28 promoters, determined experimentally, present an important -10 motif (5'-CGA-3') at the positions -12 to -10 and a distance of 6 nucleotides between the transcription start site and the -10 box 16855242. Yu HH,2006. Park K,2001. |
| Evidence: |
[HIPP] [ICWHO] |
| Reference(s): |
[1] Huerta AM., et al., 2003 [2] Zhao K., et al., 2007 |
| Reference(s) |
|
|---|---|
[HIPP] Human inference of promoter position