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Name: | pagP | ||||||||||
Synonym(s): | crcA | ||||||||||
Gene(s): | pagP Genome Browser M3D Gene expression COLOMBOS | ||||||||||
Note(s): | pagP is induced by increases in osmolarity in mature bioifilms in an RcsB-dependent manner and it also requires the GadE auxiliary regulator; its induction is not observed under planktonic conditions. Formation of a RcsB-GadE complex occurs independently of the RcsB phosphorylation cascade Szczesny M, Beloin C, Ghigo JM,2018 Based on gene expression analysis, it was shown that pagP expression is repressed by H-NS Szczesny M, Beloin C, Ghigo JM,2018 SlyA, a DNA-binding protein that inhibits H-NS activity, activates pagP transcription in mature biofilms Klitgaard RN,2018 The expression of the pagP gene appears to be indirectly regulated by the transcription factor PhoP in avian pathogenic E. coli (APEC) Song X,2019. |
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Promoter | |||||||||||
Name: | pagPp | ||||||||||
+1: | 656526 | ||||||||||
Distance from start of the gene: | 31 | ||||||||||
Sequence: |
attattctttatgttgggtctattaaggttatgttaattgtagctttgctatgctagtagTagatttttgataaatgtttt |
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Evidence: | [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] | ||||||||||
Reference(s): | [1] Eguchi Y., et al., 2004 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
proximal | PhoP-phosphorylated | activator | pagPp | 656486 | 656502 | -32.0 | atgttgggtcTATTAAGGTTATGTTAAttgtagcttt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] | W | [1] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence | Confidence level (C: Confirmed, S: Strong, W: Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | ||||||||
remote | SlyA | activator | pagPp | 656411 | 656422 | -109.5 | atctttaatcGATGCGCGGAAAtatttaactt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-PATTERN-DISCOVERY] | W | [2] |
proximal | SlyA | activator | pagPp | 656431 | 656444 | -89.0 | aatatttaacTTGAACAAGCGGAAataaatagag | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-PATTERN-DISCOVERY] | W | [2] |
proximal | SlyA | activator | pagPp | 656510 | 656523 | -10.0 | taattgtagcTTTGCTATGCTAGTagtagatttt | nd | [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-PATTERN-DISCOVERY] | W | [2] |
Reference(s) |
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