RegulonDB RegulonDB 11.2: Operon Form
   

dhaR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: dhaR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: dhaR
Gene(s): dhaR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF-SINGLE-DIRECTON] Automated inference that a single-gene directon is a transcription unit
Reference(s): [1] Bachler C., et al., 2005
Promoter
Name: dhaRp
+1: 1251003
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 63
Sequence: tagcccaaattatgtttcatagtgaaacatatgctttaatgaatgttccatattgaaactTttacgtgtattaatacttaa
                        -35                 -10             +1                   
Evidence: [COMP-AINF]
[COMP-AINF-POSITIONAL-IDENTIFICATION]
Reference(s): [2] Gama-Castro S., et al., 2008
[3] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[DhaR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd DhaR repressor dhaRp nd nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS] W [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-AINF-POSITIONAL-IDENTIFICATION] Automated inference of promoter position

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis


Reference(s)    

 [1] Bachler C., Schneider P., Bahler P., Lustig A., Erni B., 2005, Escherichia coli dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR., EMBO J 24(2):283-93

 [2] Gama-Castro S., Jimenez-Jacinto V., Peralta-Gil M., Santos-Zavaleta A., Penaloza-Spinola MI., Contreras-Moreira B., Segura-Salazar J., Muniz-Rascado L., Martinez-Flores I., Salgado H., Bonavides-Martinez C., Abreu-Goodger C., Rodriguez-Penagos C., Miranda-Rios J., Morett E., Merino E., Huerta AM., Trevino-Quintanilla L., Collado-Vides J., 2008, RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation., Nucleic Acids Res 36(Database issue):D120-4

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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