RegulonDB RegulonDB 11.1: Operon Form
   

seqA-pgm operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: seqA-pgm
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: seqA-pgm
Gene(s): seqA, pgm   Genome Browser M3D Gene expression COLOMBOS
Evidence: [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
[EXP-IMP-POLAR-MUTATION] Polar mutation
Reference(s): [1] Lu M., et al., 1994
[2] Lu M., et al., 1994
Promoter
Name: seqAp
+1: 712942
Distance from start of the gene: 45
Sequence: tattccgagtttttctgcaagccaggcttgacgctatccgctgccgggatttattcatatActcctggcgacttgtattca
Evidence: [COMP-AINF-POSITIONAL-IDENTIFICATION]
Reference(s): [1] Lu M., et al., 1994
Terminator(s)
Type: rho-independent
Sequence: acatttaataAAAAAAGGGCGGTCGCAAGATCGCCCTTTTTTacgtatgaca
Reference(s): [2] Lu M., et al., 1994
TF binding sites (TFBSs)
[HU,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd HU repressor seqAp nd nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS] W [3]


Evidence    

 [COMP-AINF-POSITIONAL-IDENTIFICATION] Automated inference of promoter position

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis


Reference(s)    

 [1] Lu M., Campbell JL., Boye E., Kleckner N., 1994, SeqA: a negative modulator of replication initiation in E. coli., Cell 77(3):413-26

 [2] Lu M., Kleckner N., 1994, Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli., J Bacteriol 176(18):5847-51

 [3] Lee H., Kim HK., Kang S., Hong CB., Yim J., Hwang DS., 2001, Expression of the seqA gene is negatively modulated by the HU protein in Escherichia coli., Mol Gen Genet 264(6):931-5

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