RegulonDB RegulonDB 11.0: Operon Form
   

acrR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: acrR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: acrR
Gene(s): acrR   Genome Browser M3D Gene expression COLOMBOS
Note(s): In an experiment using increasing concentrations of tetracycline, the transcription of the acrR gene is induced in low concentrations (1.5 and 4 mg/L), but this induction decreases in high concentrations (10 mg/L) Viveiros M, Dupont M, Rodrigues L, Couto I, Davin-Regli A, Martins M, Pagès JM, Amaral L,2007
Promoter
Name: acrRp
+1: 485699
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 62
Sequence: gatttcaaattggtcaatggtcaaaagttaataaacccattgctgcgtttatattatcgtCgtgctatggtacatacattc
                            -35                     -10     +1                   
Evidence: [AIPP]
[ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal AcrR repressor acrRp 485709 485732 22.5 cgtgctatggTACATACATTCACAAATGTATGTAaatctaacgc nd [AIBSCS], [APIORCISFBSCS], [BCE], [BPP], [GEA], [AIBSCS], [BPP] [2], [3], [4], [5]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: forward
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.8 485590 485616 aacgaccgccAGAGGCGTAAACCCTCTGTTTTTGTTcatatgtaaa
  anti-terminator -3.8 485582 485598 agcatcagaaCGACCGCCAGAGGCGTaaaccctctg
  anti-anti-terminator -12.8 485539 485586 ggcctgtttgTCGTCACATCCTGTTAGGGCTAAGCTGCCTGAGAGCATCAGAACGACcgccagaggc
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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