RegulonDB RegulonDB 10.9: Operon Form
   

pgaABCD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: pgaABCD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: pgaABCD
Gene(s): pgaD, pgaC, pgaB, pgaA   Genome Browser M3D Gene expression COLOMBOS
Note(s): The pgABCD operon was inferred based on the facts that its genes are adjacent, encoded in the same direction, and their products are all involved in biofilm formation 15090514
H-NS represses pgaA transcription, although it is unknown if the effect is direct or indirect Parker A,2017
Evidence: [IC] Inferred by curator
Promoter
Name: pgaAp
+1: 1092523
Distance from start of the gene: 234
Sequence: ccgaaatcatgcatcggaatttactgatttaattattttaatcctaatttattttgaaaaAggcattgggatttatgccgt
Evidence: [TIM]
Reference(s): [1] Goller C., et al., 2006
[2] Wang X., et al., 2005
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal NhaR-Na+ activator pgaAp 1092556 1092572 -41.0 ccgaaatcatGCATCGGAATTTACTGATttaattattt nd [APIORCISFBSCS], [BPP], [GEA] [1], [3]
proximal NhaR-Na+ activator pgaAp 1092578 1092594 -63.0 ttcatcaggaCTTTCGAAAAATCCGAAAtcatgcatcg nd [APIORCISFBSCS], [BPP], [GEA] [1], [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal OmpR-P1 repressor pgaAp 1092545 1092564 -31.5 atgcatcggaATTTACTGATTTAATTATTTTaatcctaatt nd [APIORCISFBSCS], [BPP], [GEA] [4]
Note(s): 1OmpR-P represses biofilm production by direct interaction of the pgaABCD operon through acetyl phosphate as the phosphodonor Oropeza R,20153OmpR-P represses biofilm production by direct interaction of the pgaABCD operon through acetyl phosphate as the phosphodonor Oropeza R,2015





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