RegulonDB RegulonDB 10.9: Operon Form
   

feaB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: feaB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: feaB
Gene(s): feaB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Zaslaver A., et al., 2006
Promoter
Name: feaBp2
+1: 1447370
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 149
Sequence: tttttattgttgcatttgtgttgcaataaacgaagctaatgagcctgactataggaaataAgtcttgtcaggcatagagac
                     -35                          -10       +1                   
Evidence: [TIM]
Reference(s): [2] Zeng J., et al., 2013
Terminator(s)
Type: rho-independent
Sequence: gctcataagtAAAAAACGGCACCTGGTGCCGTTTTTTtgtctgaaac
Reference(s): [3] Ferrandez A., et al., 1997


Transcription unit          
Name: feaB
Gene(s): feaB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of tynA is activated in carbon- and nitrogen-limited cells in the presence of a FeaR coactivator Zeng J,2013.
During carbon limitation in the presence of the FeaR coactivators (glycerol medium plus tyramine/PEA), both tynA and feaB are upregulated Zeng J,2013.
tynA, feaB, and fliA promoters are strongly repressed when the nsrR start codon from the wild-type GUG is changed to AUG Chhabra S,2015
Evidence: [AISGDTU] Automated inference that a single-gene directon is a transcription unit
[BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Zaslaver A., et al., 2006
Promoter
Name: feaBp1
+1: 1447492
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 27
Sequence: gacaaagcgaatgtcacagcgaaaaaagtgacttttcttgtcgctgcgtacactgaaatcAcactgggtaaataataagga
                            -35                  -10        +1                   
Note(s): Zaslaver et al. demonstrated in 2006, by means of a library of fluorescent transcription fusions, that this promoter can be transcribed in vitro Zaslaver A,2006.
Evidence: [IHBCE]
[TIM]
Reference(s): [3] Ferrandez A., et al., 1997
[1] Zaslaver A., et al., 2006
[2] Zeng J., et al., 2013
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP activator feaBp1 1447410 1447431 -71.5 tattgtcacgATTTGCGGAGCTTGTCACAGCTGacaaagcgaa nd [APIORCISFBSCS], [GEA], [APIORCISFBSCS] [6]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FeaR activator feaBp1 1447418 1447438 -64.0 cgatttgcggAGCTTGTCACAGCTGACAAAGCgaatgtcaca nd [APIORCISFBSCS], [BPP], [GEA], [SM] [2], [7]
proximal FeaR activator feaBp1 1447439 1447459 -43.0 gctgacaaagCGAATGTCACAGCGAAAAAAGTgacttttctt nd [APIORCISFBSCS], [BPP], [GEA], [SM] [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote NsrR repressor feaBp1 1447303 1447314 -184.0 tcgctctgtgAAATGTATTTTTattgttgcat nd [APIORCISFBSCS], [GEA] [4], [5]





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